Dr. Wondisford’s research interests include:
- Pituitary and hypothalamic gene expression and molecular mechanisms responsible for hormonal regulation
- Growth-factor regulation of the anterior pituitary gland and pancreas
- Molecular mechanism of thyroid hormone action in the brain
- Role of co-activators in pancreatic B-cell transcription and development
- Molecular mechanism of peroxisome proliferator-activated receptor gamma (PPARg) action in the adipocyte
- Regulation of hepatic gluconeogenesis by transcriptional co-factors
Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. "An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo." Endocrinology. 2008;149(6):2970-9.
Pessôa CN, Santiago LA, Santiago DA, Machado DS, Rocha FAF, Ventura DF, Hokoç JN, Pazos-Moura CC, Wondisford FE, Gardino PF, Ortiga-Carvalho TM. "Thyroid hormone action is required for normal cone opsin expression during mouse retinal development." Investigative ophthalmology & visual science. 2008;49(5):2039-45.
Divall SA, Wondisford FE. "TRH testing in its infancy." The Journal of clinical endocrinology and metabolism. 2008;93(2):378-9.
Applebury ML, Farhangfar F, Glösmann M, Hashimoto K, Kage K, Robbins JT, Shibusawa N, Wondisford F E, Zhang H. "Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis." Developmental dynamics : an official publication of the American Association of Anatomists. 2007;236(5):1203-12.
Hussain MA, Porras DL, Rowe MH, West JR, Song WJ, Schreiber WE, Wondisford FE. "Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation." Molecular and cellular biology. 2006;26(20):7747-59.