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Robert Albert Anders, M.D., Ph.D.

Photo of Dr. Robert Albert Anders, M.D., Ph.D.

Associate Professor of Pathology

Male

Expertise: Pathology

Research Interests: Gastrointestinal and Liver Pathology; Liver cancer; Liver cell death and division

Locations

The Johns Hopkins Hospital (Main Entrance)

1800 Orleans St.
Baltimore, MD 21287 map
Phone: 410-955-9790

Background

Dr. Robert Albert Anders is an associate professor of pathology at the Johns Hopkins University School of Medicine and a member of the Johns Hopkins Kimmel Cancer Center. His clinical expertise includes pathology.

Dr. Anders received his M.D. from Mayo Clinic Medical School College of Medicine. He completed his residency in anatomic and clinical pathology and a fellowship in pathology from the University of Chicago Hospitals.

His research interests include gastrointestinal and liver pathology.

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Titles

  • Associate Professor of Pathology
  • Assistant Professor of Oncology

Education

Degrees

  • MD, Mayo Medical School College of Medicine (1998)

Residencies

  • University of Chicago Hospitals / Anatomic and Clinical Pathology (2002)

Fellowships

  • University of Chicago Hospitals / Pathology (2004)

Board Certifications

  • American Board of Pathology / Anatomic & Clinical Pathology (2002)

Research & Publications

Research Summary

Dr. Anders’ laboratory focuses on the basic processes that lead to liver cell death and division. His team approaches these questions through the use of both experimental models and examination of human tissues. His team is specifically interested in how the Hippo pathway controls the livers response to injury and malignant transformation. They have uncovered this pathway as a key mediator of hepatocyte and cholangiocyte biology.

Selected Publications

View all on Pubmed

Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Translational Medicine. 2012 Mar 28;4(127):127ra37. PMID: 22461641. PMCID: PMC3568523

Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz LA Jr. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. The New England journal of medicine. 2015 Jun 25;372(26):2509-20. Epub 2015 May 30. PMID: 26028255. PMCID: PMC4481136

Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, Stankevich E, Pons A, Salay TM, McMiller TL, Gilson MM, Wang C, Selby M, Taube JM, Anders RA, Chen L, Korman AJ, Pardoll DM, Lowy I, Topalian SL. Phase I study of single-agent anti–programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. Journal of Clinical Oncology. 2010 Jul 1;28(19):3167-75. Epub 2010 Jun 1. PMID: 20516446

Jiao Y, Pawlik TM, Anders RA, Selaru FM, Streppel MM, Lucas DJ, Niknafs N, Guthrie VB, Maitra A, Argani P, Offerhaus GJ, Roa JC, Roberts LR, Gores GJ, Popescu I, Alexandrescu ST, Dima S, Fassan M, Simbolo M, Mafficini A, Capelli P, Lawlor RT, Ruzzenente A, Guglielmi A, Tortora G, de Braud F, Scarpa A, Jarnagin W, Klimstra D, Karchin R, Velculescu VE, Hruban RH, Vogelstein B, Kinzler KW, Papadopoulos N, Wood LD. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nature Genetics. 2013 Dec;45(12):1470-3. Epub 2013 Nov 3. PMID: 24185509. PMCID: PMC4013720

Steinhardt AA, Gayyed MF, Klein AP, Dong J, Maitra A, Pan D, Montgomery EA, Anders RA. Expression of Yes-associated protein, in common solid tumors. Human Pathology. 2008 Nov;39(11):1582-9. Epub 2008 Aug 13. PMID: 18703216. PMCID: PMC2720436

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