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Francesco Boin, MD

Director, Scleroderma Center Translational Research
Assistant Professor of Medicine

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The Johns Hopkins Hospital

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  • Director, Scleroderma Center Translational Research
  • Assistant Professor of Medicine

Centers & Institutes

  • Scleroderma Center


Rheumatology, Scleroderma

Research Interests

Eosinophilic fasciitis; Morphea; Scleroderma


Dr. Boin received his M.D. degree from the University of Padova Medical School (Italy). He completed his internship and residency in internal medicine at the Mayo Clinic (Rochester, Minnesota) and a post-doctoral fellowship in clinical and experimental rheumatology at Johns Hopkins University.

Dr. Boin is interested in Translational Research: studies that apply basic research technology directly to study patients’ clinical disease.

Dr. Boin is also interested in other immune-mediated fibrosing skin disorders and with particular focus on a condition called eosinophilic fasciitis.


  • English
  • Italian
Additional Resources +
  • Education +


    • Gap in Chronology () (1996)
    • University of Padua College of Medicine and Surgery (Padua) (1993)


    • Mayo Clinic Medical School College of Medicine / Internal Medicine (Rochester MN ) (2003)
    • IRCCS - Fatebenefratelli (Brescia) (2000)
    • University of Padua College of Medicine and Surgery / Allergy and Clinical Immunology (Padua) (1998)
    • University of Padua College of Medicine and Surgery / Allergy and Clinical Immunology (Padua) (1995)


    • Johns Hopkins University School of Medicine / Rheumatology (Baltimore MD ) (2006)


    • Rheumatology, American Board of Internal Medicine (2005)
  • Research & Publications +

    Research Summary

    Dr. Boin’s research focuses on the cellular biology of immune cells and the mechanisms of autoimmunity in scleroderma. His goal is to identify reliable laboratory tools that can help investigate the causes of scleroderma, effectively measure disease activity, monitor treatments and help predict clinical outcomes in scleroderma patients.

    Selected Publications View all on PubMed

    1. Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer. Science. 2013 Dec 5. [Epub ahead of print] PMID: 24310608
    2. Gelber AC, Manno RL, Shah AA, Woods A, Le EN, Boin F, Hummers LK, Wigley FM. Race and association with disease manifestations and mortality in scleroderma: a 20-year experience at the Johns Hopkins Scleroderma Center and review of the literature. Medicine (Baltimore). 2013 Jul;92(4):191-205. doi: 10.1097/MD.0b013e31829be125. Review. PMID: 23793108 
    3. Cottrell TR, Wise RA, Wigley FM, Boin F. The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis. Ann Rheum Dis. 2013 Apr 20. [Epub ahead of print] PMID: 23606705
    4. Shah AA, Schiopu E, Hummers LK, Wade M, Phillips K, Anderson C, Wise R, Boin F, Seibold JR, Wigley F, Rollins KD. Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion. Arthritis Res Ther. 2013 Apr 18;15(2):R54. [Epub ahead of print] PMID: 23597147
    5. Fava A, Wung PK, Wigley FM, Hummers LK, Daya NR, Ghazarian SR, Boin F. Efficacy of Rho kinase inhibitor fasudil in secondary Raynaud's phenomenon. Arthritis Care Res (Hoboken). 2012 Jun;64(6):925-9. doi: 10.1002/acr.21622. Epub 2012 Jan 24. PMID: 22275160
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  • Contact & Locations +


    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-550-7715
    Appointment Phone: 410-550-7715
    Fax: 410-550-1363
    Location Map


    • Medicine - Clinical and Molecular Rheumatology

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