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Photo of Dr. Thomas Grader-Beck, M.D., Ph.D.

Thomas Grader-Beck, M.D., Ph.D.

Assistant Professor of Medicine

Male  | Languages: English, French, German

Appointment Phone


Main Location

Good Samaritan Professional Building

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Assistant Professor of Medicine



Good Samaritan Professional Building

Appointment Phone: 443-444-4646

5601 Loch Raven Boulevard
Russell Morgan Suite 507
Baltimore, MD 21239 map
Phone: 443-444-4646
Fax: 410-630-7496

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-1887

4940 Eastern Avenue
Sjogrens Center
Baltimore, MD 21224 map
Phone: 410-550-1887
Fax: 410-550-6255

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-8089

5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map
Phone: 410-550-8089
Fax: 410-550-5601


Rheumatology, Sjogren's Syndrome, Systemic Lupus Erythematosus

Research Interests

Pathogenesis of systemic autoimmune diseases, systemic lupus erythematosus and Sjogren''s


Dr. Grader-Beck is an Assistant Professor of Medicine in the Rheumatology Division. 

Dr. Grader-Beck’s clinical interests include systemic lupus erythematosus and Sjögren’s syndrome, with emphasis on complex patients that are difficult to treat, as well as patients with vaginal sicca. more

    Additional Information

  • Education +


    • Heidelberg University School of Medicine / MD (1997)


    • University of Massachusetts Medical Center / Internal Medicine (2003)


    • Dana-Farber Cancer Institute (2000)
    • Johns Hopkins University School of Medicine / Rheumatology (2006)


    • American Board of Internal Medicine / Rheumatology (2005)
  • Research & Publications +

    Research Summary

    His research interests include systemic lupus erythematosus and Sjögren’s syndrome. The pathogenesis of SLE and Sjogren’s syndrome, two closely related and common systemic autoimmune diseases, remains unknown. Antibodies that target self-molecules (autoantibodies) are thought to play an important role in the disease process. Dr. Grader-Beck’s laboratory is investigating mechanisms that may render self-structures immunogenic and hypothesizes that specific posttranslational modifications of antigens that may occur during infections or malignant transformation lead to expression of neoepitopes that propagate autoimmunity in the right setting. By combining studies using a variety of mouse strains, specific gene-deficient mice as well as human biological specimens, Dr. Grader-Beck’s team is taking a translational approach to answer these questions.

  • Academic Affiliations & Courses +
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