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Photo of Dr. Venkataramana Sidhaye

Venkataramana K Sidhaye, M.D.

Assistant Professor of Medicine


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Assistant Professor of Medicine

Centers & Institutes

  • Microscopy/Confocal Imaging Core



The Johns Hopkins Hospital

Appointment Phone: 410-550-5864

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-550-5864

601 N. Caroline Street
Baltimore, MD 21287 map

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864

4940 Eastern Avenue
Baltimore, MD 21224 map


Internal Medicine, Pulmonary Medicine

Research Interests

Airway epithelial biology; Lung epithelial biology; Airway epithelial permeability; Aquaporins in the lung


Dr. Venkataramana Sidhaye is an assistant professor of medicine at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include internal medicine and pulmonary medicine. 

Dr. Sidhaye serves as the associate director of the Pulmonary and Critical Care Medicine Fellowship Training Program at Johns Hopkins.

She received her M.D. from the Feinberg School of Medicine at Northwestern University. She completed her residency at Northwestern and performed a fellowship in pulmonary and critical care medicine at Johns Hopkins.

Dr. Sidhaye's research interests include airway epithelial biology, lung epithelial biology, airway epithelial permeability and aquaporins in the lung. more

    Additional Information

  • Education +


    • Northwestern University The Feinberg School of Medicine / MD (1998)


    • Northwestern University Medical School / Internal Medicine (2002)


    • Johns Hopkins University School of Medicine / Pulmonary and Critical Care Medicine (2006)


    • American Board of Internal Medicine / Critical Care Medicine (2007)
    • American Board of Internal Medicine / Pulmonary Disease (2006)
  • Research & Publications +

    CORE Facilities

    Microscopy/Confocal Imaging Core

    Selected Publications View all on PubMed

    Sussan TE, Gajghate S, Chatterjee S, Mandke P, McCormick S, Sudini K, Kumar S, Breysse PN, Diette GB, Sidhaye VK, Biswal S. "Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function." Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L27-36. doi: 10.1152/ajplung.00398.2014. Epub 2015 May 8.

    Brune K, Frank J, Schwingshackl A, Finigan J, Sidhaye VK. "Pulmonary epithelial barrier function: some new players and mechanisms." Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L731-45. doi: 10.1152/ajplung.00309.2014. Epub 2015 Jan 30. Review.

    Sebastian R, Chau E, Fillmore P, Matthews J, Price LA, Sidhaye V, Milner SM. "Epidermal aquaporin-3 is increased in the cutaneous burn wound." Burns. 2015 Jun;41(4):843-7. doi: 10.1016/j.burns.2014.10.033. Epub 2015 Jan 18.

    Singer BD, Mock JR, Aggarwal NR, Garibaldi BT, Sidhaye VK, Florez MA, Chau E, Gibbs KW, Mandke P, Tripathi A, Yegnasubramanian S, King LS, D'Alessio FR. "Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation." Am J Respir Cell Mol Biol. 2015 May;52(5):641-52. doi: 10.1165/rcmb.2014-0327OC.

    Mock JR, Garibaldi BT, Aggarwal NR, Jenkins J, Limjunyawong N, Singer BD, Chau E, Rabold R, Files DC, Sidhaye V, Mitzner W, Wagner EM, King LS, D'Alessio FR. "Foxp3+ regulatory T cells promote lung epithelial proliferation." Mucosal Immunol. 2014 Nov;7(6):1440-51. doi: 10.1038/mi.2014.33. Epub 2014 May 21.

    Aggarwal NR, Tsushima K, Eto Y, Tripathi A, Mandke P, Mock JR, Garibaldi BT, Singer BD, Sidhaye VK, Horton MR, King LS, D'Alessio FR. "Immunological priming requires regulatory T cells and IL-10-producing macrophages to accelerate resolution from severe lung inflammation." J Immunol. 2014 May 1;192(9):4453-64. doi: 10.4049/jimmunol.1400146. Epub 2014 Mar 31.

    Lai N, Lade J, Leggett K, Yun X, Baksh S, Chau E, Crow MT, Sidhaye V, Wang J, Shimoda LA. The Aquaporin 1 C-terminal Tail is Required for Migration and Growth of Pulmonary Arterial Myocytes. Am J Respir Cell Mol Biol. 2013 Dec 11. [Epub ahead of print] PMID: 24328827

    Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. MK2 Mediates Apoptosis During Lung Vascular Permeability by Regulating Movement of Cleaved Caspase 3. Am J Respir Cell Mol Biol. 2013 Dec 4. [Epub ahead of print] PMID: 24304496

    Aggarwal NR, D'Alessio FR, Eto Y, Chau E, Avalos C, Waickman AT, Garibaldi BT, Mock JR, Files DC, Sidhaye V, Polotsky VY, Powell J, Horton M, King LS. Macrophage A2A adenosinergic receptor modulates oxygen-induced augmentation of murine lung injury. Am J Respir Cell Mol Biol. 2013 May;48(5):635-46. doi: 10.1165/rcmb.2012-0351OC. PMID: 23349051

    Garibaldi BT, D'Alessio FR, Mock JR, Files DC, Chau E, Eto Y, Drummond MB, Aggarwal NR, Sidhaye V, King LS. Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment. Am J Respir Cell Mol Biol. 2013 Jan;48(1):35-43. doi: 10.1165/rcmb.2012-0198OC. Epub 2012 Sep 20. PMID: 23002097

    D'Alessio FR, Tsushima K, Aggarwal NR, Mock JR, Eto Y, Garibaldi BT, Files DC, Avalos CR, Rodriguez JV, Waickman AT, Reddy SP, Pearse DB, Sidhaye VK, Hassoun PM, Crow MT, King LS. Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase. J Immunol. 2012 Sep 1;189(5):2234-45. doi: 10.4049/jimmunol.1102606. Epub 2012 Jul 27. PMID: 22844117

    Chau E, Galloway JF, Nelson A, Breysse PN, Wirtz D, Searson PC, Sidhaye VK. Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro. Nanotoxicology. 2013 Sep;7(6):1143-51. doi: 10.3109/17435390.2012.711862. Epub 2012 Aug 20. PMID: 22783847

    Sidhaye VK, Chau E, Srivastava V, Sirimalle S, Balabhadrapatruni C, Aggarwal NR, D'Alessio FR, Robinson DN, King LS. A novel role for aquaporin-5 in enhancing microtubule organization and stability. PLoS One. 2012;7(6):e38717. doi: 10.1371/journal.pone.0038717. Epub 2012 Jun 8. PMID: 22715407 [PubMed - in process]

    Leggett K, Maylor J, Undem C, Lai N, Lu W, Schweitzer K, King LS, Myers AC, Sylvester JT, Sidhaye V, Shimoda LA. Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L343-53. doi: 10.1152/ajplung.00130.2012. Epub 2012 Jun 8. PMID: 22683574

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