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Paul M Hassoun, MD

Director, Pulmonary Hypertension Program
Professor of Medicine

See Research on Pubmed

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Main Location

The Johns Hopkins Hospital

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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Director, Pulmonary Hypertension Program
  • Professor of Medicine


Critical Care Medicine, Pulmonary Disease and Critical Care Medicine, Pulmonary Hypertension

Research Interests

Pulmonary hypertension/Scleroderma-associated pulmonary hypertension/; Molecular determinants of pulmonary hypertension; Regulation and role of xanthine oxidase in lung injury; Acute lung injury


  • English
  • French
  • Arabic


American Thoracic Society
Massachusetts Thoracic Society
American Heart Association
European Respiratory Society
Physicians for Human Rights
Fellow, American College of Chest Physicians
Maryland Thoracic Society

Additional Resources

Additional Resources +
  • Education +


    • Faculte' de Medecine Lariborsiere - (Paris) (1981)


    • Brigham and Women's Hospital (Boston MA ) (1984)


    • Tufts - New England Medical Center Hospitals (Boston MA ) (1988)
    • Massachusetts General Hospital (Boston MA ) (1987)


    • Pulmonary Disease, American Board of Internal Medicine (1986)
    • Internal Medicine, American Board of Internal Medicine (1984)
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. MK2 Mediates Apoptosis During Lung Vascular Permeability by Regulating Movement of Cleaved Caspase 3. Am J Respir Cell Mol Biol. 2013 Dec 4. [Epub ahead of print] PMID: 24304496 
    2. Nathan SD, Hassoun PM. Pulmonary Hypertension due to Lung Disease and/or Hypoxia. Clin Chest Med. 2013 Dec;34(4):695-705. doi: 10.1016/j.ccm.2013.08.004. Epub 2013 Oct 17. PMID: 24267299 [PubMed - in process]
    3. Chaisson NF, Hassoun PM. Systemic sclerosis-associated pulmonary arterial hypertension. Chest. 2013 Oct;144(4):1346-56. doi: 10.1378/chest.12-2396. PMID: 24081346 [PubMed - in process]
    4. Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369 
    5. Hassoun PM, Shafiq M. Tackling the challenges of systemic sclerosis-associated pulmonary hypertension: one step forward. Arthritis Rheum. 2013 Sep;65(9):2240-2. doi: 10.1002/art.38031. No abstract available. PMID: 23740649 
    6. Hassoun PM, Nikkho S, Rosenzweig EB, Moreschi G, Lawrence J, Teeter J, Meier C, Ghofrani AH, Minai O, Rinaldi P, Michelakis E, Oudiz RJ. Updating clinical endpoint definitions. Pulm Circ. 2013 Jan;3(1):206-16. doi: 10.4103/2045-8932.109920. PMID: 23662199 
    7. Hoeper MM, Barst RJ, Bourge RC, Feldman J, Frost AE, Galié N, Gómez-Sánchez MA, Grimminger F, Grünig E, Hassoun PM, Morrell NW, Peacock AJ, Satoh T, Simonneau G, Tapson VF, Torres F, Lawrence D, Quinn DA, Ghofrani HA. Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation. 2013 Mar 12;127(10):1128-38. doi: 10.1161/CIRCULATIONAHA.112.000765. Epub 2013 Feb 12. PMID: 23403476
    8. Mathai SC, Hassoun PM. Drs. Mathai and Hassoun reply. J Rheumatol. 2013 Jan;40(1):91. No abstract available. PMID: 23401876 
    9. Kim BS, Serebreni L, Hamdan O, Wang L, Parniani A, Sussan T, Scott Stephens R, Boyer L, Damarla M, Hassoun PM, Damico R. Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis. Free Radic Biol Med. 2013 Jul;60:336-46. doi: 10.1016/j.freeradbiomed.2013.01.023. Epub 2013 Feb 4. PMID: 23380026 
    10. Shehata ML, Harouni AA, Skrok J, Basha TA, Boyce D, Lechtzin N, Mathai SC, Girgis R, Osman NF, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study. Radiology. 2013 Jan;266(1):114-22. doi: 10.1148/radiol.12111599. Epub 2012 Nov 14. PMID: 23151825
  • Academic Affiliations & Courses +
  • Activities & Honors +


    The David M Levine Excellence in Mentoring Award, Johns Hopkins University Department of Medicine, 2008 

    Chair, Program Committee, Pulmonary Circulation, American Thoracic Society, 2008 

    Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award, 2002 

    Tufts University School of Medicine, Third Year Clerkship, Excellence in Teaching Award, 2001 

    Oliver Smith Award (Recognizing excellence, compassion, and extraordinary service and caring at the New England Medical Center), 2001 

    Recipient of Edward Livingston Trudeau Scholar Award: declined due to acceptance of Clinical Investigator Award, 1988-1990 

    Recipient of the Winthrop-Breon/ACCP Scholar Award for Outstanding Original Scientific Research, American Lung Association/American Thoracic Society, 1986 

  • Videos & Media +
  • Events +
  • Contact & Locations +


    The Johns Hopkins Hospital
    600 N. Wolfe Street
    1830 Building
    5th Floor
    Baltimore, MD 21287
    Phone: 410-955-3467
    Appointment Phone: 410-550-5864
    Fax: 410-614-7451
    Location Map
    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Baltimore, MD 21224
    Phone: 410-550-0545
    Appointment Phone: 410-550-5864
    Fax: 410-550-2612
    Location Map
    Johns Hopkins Outpatient Center
    601 N. Caroline Street
    Baltimore, MD 21287
    Appointment Phone: 410-955-3467
    Fax: 410-614-7451
    Location Map


    • Medicine - Pulmonary and Critical Care Medicine

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