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Photo of Dr. Paul M Hassoun, M.D.

Paul M Hassoun, M.D.

Director, Pulmonary Hypertension Program
Professor of Medicine

Male  | Languages: English, Arabic, French

Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Director, Pulmonary Hypertension Program
  • Professor of Medicine



The Johns Hopkins Hospital

Appointment Phone: 410-550-5864

1830 E. Monument Street
1830 Building 5th Floor Pulmonary
Baltimore, MD 21287 map
Phone: 410-955-3467
Fax: 410-614-7451

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864

4940 Eastern Avenue
Baltimore, MD 21224 map
Phone: 410-550-0545
Fax: 410-550-2612

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-3467

601 N. Caroline Street
Baltimore, MD 21287 map
Fax: 410-614-7451


Critical Care Medicine , Pulmonary Disease and Critical Care Medicine, Pulmonary Hypertension

Research Interests

Acute lung injury; Regulation and role of xanthine oxidase in lung injury; Molecular determinants of pulmonary hypertension; Pulmonary hypertension/Scleroderma-associated pulmonary hypertension/

    Additional Information

  • Education +


    • Faculte' de Medecine Lariborsiere - / MD (1981)


    • Brigham and Women's Hospital (1984)


    • Massachusetts General Hospital (1987)
    • Tufts -New England Medical Center Hospitals (1988)


    • American Board of Internal Medicine / Internal Medicine (1984)
    • American Board of Internal Medicine / Pulmonary Disease (1986)
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. MK2 Mediates Apoptosis During Lung Vascular Permeability by Regulating Movement of Cleaved Caspase 3. Am J Respir Cell Mol Biol. 2013 Dec 4. [Epub ahead of print] PMID: 24304496
    2. Nathan SD, Hassoun PM. Pulmonary Hypertension due to Lung Disease and/or Hypoxia. Clin Chest Med. 2013 Dec;34(4):695-705. doi: 10.1016/j.ccm.2013.08.004. Epub 2013 Oct 17. PMID: 24267299 [PubMed - in process]
    3. Chaisson NF, Hassoun PM. Systemic sclerosis-associated pulmonary arterial hypertension. Chest. 2013 Oct;144(4):1346-56. doi: 10.1378/chest.12-2396. PMID: 24081346 [PubMed - in process]
    4. Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369
    5. Hassoun PM, Shafiq M. Tackling the challenges of systemic sclerosis-associated pulmonary hypertension: one step forward. Arthritis Rheum. 2013 Sep;65(9):2240-2. doi: 10.1002/art.38031. No abstract available. PMID: 23740649
    6. Hassoun PM, Nikkho S, Rosenzweig EB, Moreschi G, Lawrence J, Teeter J, Meier C, Ghofrani AH, Minai O, Rinaldi P, Michelakis E, Oudiz RJ. Updating clinical endpoint definitions. Pulm Circ. 2013 Jan;3(1):206-16. doi: 10.4103/2045-8932.109920. PMID: 23662199
    7. Hoeper MM, Barst RJ, Bourge RC, Feldman J, Frost AE, Galié N, Gómez-Sánchez MA, Grimminger F, Grünig E, Hassoun PM, Morrell NW, Peacock AJ, Satoh T, Simonneau G, Tapson VF, Torres F, Lawrence D, Quinn DA, Ghofrani HA. Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation. 2013 Mar 12;127(10):1128-38. doi: 10.1161/CIRCULATIONAHA.112.000765. Epub 2013 Feb 12. PMID: 23403476
    8. Mathai SC, Hassoun PM. Drs. Mathai and Hassoun reply. J Rheumatol. 2013 Jan;40(1):91. No abstract available. PMID: 23401876
    9. Kim BS, Serebreni L, Hamdan O, Wang L, Parniani A, Sussan T, Scott Stephens R, Boyer L, Damarla M, Hassoun PM, Damico R. Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis. Free Radic Biol Med. 2013 Jul;60:336-46. doi: 10.1016/j.freeradbiomed.2013.01.023. Epub 2013 Feb 4. PMID: 23380026
    10. Shehata ML, Harouni AA, Skrok J, Basha TA, Boyce D, Lechtzin N, Mathai SC, Girgis R, Osman NF, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study. Radiology. 2013 Jan;266(1):114-22. doi: 10.1148/radiol.12111599. Epub 2012 Nov 14. PMID: 23151825
  • Academic Affiliations & Courses +
  • Activities & Honors +


    • Winthrop Breon/ACCP Scholar Award, American Lung Association/American Thoracic Society, 1986
    • Clinical Investigator Award, 1988 - 1990
    • Excellence in Teaching Award, Tufts University School of Medicine, 2001
    • Oliver Smith Award, New England Medical Center, 2001
    • Excellence in Teaching Award, Tufts University School of Medicine, 2002
    • Chair, American Thoracic Society, 2008
    • The David M Levine Excellence in Mentoring Award, Johns Hopkins University Department of Medicine, 2008


    • American Heart Association
    • American Thoracic Society
    • European Respiratory Society
    • Fellow, American College of Chest Physicians
    • Maryland Thoracic Society
    • Massachusetts Thoracic Society
    • Physicians for Human Rights
  • Videos & Media +
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