Research & Publications +
NIH/NINDS RO-1, Funded, Principal Investigator 1R01NS062059-01A1, GRANT00431125, Occult Small Vessel Cerebrovascular Disease in High Risk Families.
Investigator / Inteventional Management of Stroke (IMS) III NIH Sponsored Clinical Trial
Principal Investigator/ Clinical Trial of rFVIIa (Novoseven) in Patients with
Intracerebral Hemorrhage at Johns Hopkins University, Sponsored by NOVONORDISK
Principal Investigator/ Desmotaplase in Acute Stroke at Johns Hopkins University (DIAS), Sponsored by Forest Pharmaceuticals
Investigator, CLEAR, Use of rt-PA for the Resolution of Clot in Intra-
ventricular Hemorrhage, Sponsored by FDA Orphan Drug Program
Investigator / CREST, Carotid Revascularization Endarterectomy vs. Stent Trial, NIH Sponsored Clinical Trial
Principal Investigator/ Siblings with Ischemic Stroke Study Stroke, INOVA Fairfax Hospital
Department of Defense Sponsored Research Projects
Principle Investigator, Project Officer-1993-1996: Complement Levels in Experimental Divers Before and After Dives with a High Predicted Risk of Decompression Sickness.
Project Officer, Principle Investigator -1994-1996: Desmopressin in Submersion Diueresis in Dives of Long Duration.
Project Officer-1995 - 1997: Human Decompression Trial with 1.3 ATA Oxygen in Helium.63713N.M0099.01A.1510.
Medical Monitor-1995 - 1997: Hyperbarcia Recognition and Thermal Status of Exercising Divers Exposed to Cold Water and Elevated PCO2. 63713N.M0099.01B.1428.
Paul A. Nyquist MD, MPH , Cherie A. Winkler, PhD , Louise M. McKenzie, PhD , Lisa R. Yanek, MPH , Lewis C. Becker, MD , Diane M. Becker, ScD, MPH Single Nucleotide Polymorphisms in Monocyte Chemoattractant Protein-1 and its Receptor Act Synergistically to Increase the Risk of Carotid Atherosclerosis, Cerebrovascular Disease, accepted.
Paul A Nyquist, Wityck R., Lisa R. Yanek, David Yousem, Lewis C. Becker, Diane M. Becker, High Prevalence of Silent Small Vessel Cerebrovascular Disease and Co-occurrence with Occult Coronary Disease in Healthy Individuals from High Risk Families. Neuroepidemiology accepted
Nyquist P, Stevens RD, Mirski MA. Neurologic injury and mechanical ventilation.
Neurocrit Care. 2008;9(3):400-8. Epub 2008 Aug 12
Stevens RD, Nyquist PA.Types of brain dysfunction in critical illness. Neurol Clin. 2008 May;26(2):469-86, ix
Naval NS, Nyquist PA, Carhuapoma JR.Management of spontaneous intracerebral hemorrhage. Neurol Clin. 2008 May;26(2):373-84, vii.
Toung TJ, Nyquist P, Mirski MA. Effect of hypertonic saline concentration on cerebral and visceral organ water in an uninjured rodent model. Crit Care Med. 2007 Oct 23;
Nyquist P, LeDroux S, Geocadin R. Thrombolytics in intraventricular hemorrhage. Curr Neurol Neurosci Rep. 2007 Nov;7(6):522-8.
Nyquist P, Ball R, Sheridan MJ, Complement levels before and after dives with a high risk of DCS,Undersea Hyperbaric Medicine, UHM 2007, 34(3), 191.
Stevens RD, Nyquist PA. Coma, delirium, and cognitive dysfunction in critical illness.
Crit Care Clin. 2006 Oct;22(4):787-804;
Nyquist PA, Ball R, Sheridan MJ. Complement levels before and after dives with a high predicted risk of decompression sickness. Naval Medical Research Center, Silver Spring, MD. Technical report No. 2006-001; June 2006.
Nyquist P.A., Buttolph T, Dick C., "Detection of leukocyte activation in pigs with neurologic decompression sickness", Aviat Space Environ Med. 2004 Mar;75(3):211-4.
Lattimore SU, Chalela J, Davis L, Degraba T, Ezzeddine M, Haymore J, Nyquist P, Baird AE, Hallenbeck J, Warach S, Impact of establishing a primary stroke center at a community hospital on the use of thrombolytic therapy: the NINDS Suburban Hospital Stroke Center experience. Stroke. 2003 Jun;34(6): 2003 May 15
Worrall BB, Azhar S, Nyquist PA, Ackerman RH, Hamm TL, DeGraba TJ. Interleukin-1 receptor antagonist gene polymorphisms in carotid atherosclerosis. Stroke. 2003 Mar;34(3):790-3
Nyquist PA, Cascino GD, McClelland RL, Annegers JF, Rodriguez M. Incidence of seizures in patients with multiple sclerosis: a population-based study. Mayo Clin. Proc. 2002 Sep;77(9):910-2.
Nyquist PA, Cascino GD, Rodriguez M. Seizures in patients with multiple sclerosis seen at Mayo Clinic, Rochester, Minn., 1990-1998. Mayo Clin. Proc. 2001 Oct;76(10):983-6.
Nyquist P.A., R.D. Brown, Jr., D.O. Wiebers, C.S. Crowson, and W.M. OFallon Circadian and seasonal occurrence of subarachnoid and intracerebral hemorrhage
Neurology. 2001 56: 190-193.
Nyquist P, Laws ER, Elliot E, Novel features of tumors that secrete both growth hormone and prolactin in acromegally, Neurosurgery. Vol. 35, No. 2, 179-185, 1995.