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Michelle M. Estrella, MD MHS

Michelle Mae Estrella, MD MHS
Associate Fellowship Program Director
Assistant Professor of Medicine
Appointment Phone


Main Location

The Johns Hopkins Hospital

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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Associate Fellowship Program Director
  • Assistant Co-Director of the Renal Disease Epidemiology Training Program
  • Assistant Professor of Medicine


Epidemiology, Kidney Diseases, Nephrology

Research Interests

Kidney disease; HIV research; Epidemiology; Genetics; MACS; WIHS; NA-ACCORD


  • English


American Society of Nephrology

National Kidney Foundation

Additional Resources +
  • Education +


    • Johns Hopkins University Bloomberg School of Public Health (Baltimore MD) (2009)
    • University of Texas Medical School at Houston (Houston TX) (2001)


    • Johns Hopkins University School of Medicine / Internal Medicine (Baltimore MD) (2004)


    • Johns Hopkins University School of Medicine / Nephrology (Baltimore MD) (2006)


    • American Board of Internal Medicine / Nephrology (2006)
    • American Board of Internal Medicine / Internal Medicine (2004)
  • Research & Publications +

    Research Summary

    My research interests include epidemiological and translational studies focused on kidney disease and its consequences, particularly among HIV-infected individuals. In addition, I am interested in the discovery and utility of renal biomarkers in the context of several kidney diseases and in the epidemiological research of chronic kidney disease and nephrotic syndromes.

    Selected Publications

    1. Gregory M Lucas; Yuezhou Jing; Mark Sulkowski; Alison G Abraham; Michelle M Estrella; Mohamed G Atta; Derek M Fine; Marina B Klein; Michael J Silverberg; M John Gill; et al. Hepatitis C viremia and the risk of chronic kidney disease in HIV-infected individuals. The Journal of infectious diseases 2013;208(8):1240-9. 2013 
    2. Michelle M Estrella; Christina M Wyatt; C Leigh Pearce; Man Li; Michael G Shlipak; Bradley E Aouizerat; Deborah Gustafson; Mardge H Cohen; Stephen J Gange; W H Linda Kao; et al. Host APOL1 genotype is independently associated with proteinuria in HIV infection. Kidney international 2013;84(4):834-40. 2013 
    3. Vasantha Jotwani; Rebecca Scherzer; Alison G Abraham, Michelle M Estrella; Michael Bennett; Prasad Devarajan; Kathyrn Anastos; Margaret H Cohen, Nowicki M; Anjali Sharma; Mary Young; Phyllis C Tien; Carl Grunfeld; Chirag R Parikh; Michael G Shlipak. Does HIV infection promote early kidney injury? Antiviral Therapy. 2013 Aug 23. doi: 10.3851/IMP2677
    4. Bhavna Bhasin; Bryan Lau; Mohamed G Atta; Derek M Fine; Michelle M Estrella; George J Schwartz; Greg M. Lucas. HIV Viremia and T-Cell Activation Differentially Affect the Performance of Glomerular Filtration Rate Equations Based on Creatinine and Cystatin C. PLOSOne 2013; Dec 23;8(12):e82028. doi:  10.1371/journal.pone. 0082028.
    5. Alison G Abraham; Xiuhong Li; Lisa P Jacobson; Michelle M Estrella; Rhobert W Evans; Mallory D Witt; John Phair; Antiretroviral therapy-induced changes in plasma lipids and the risk of kidney dysfunction in HIV-infected men. AIDS research and human retroviruses 2013;29(10):1346-52. 2013 
    6. Todd H Driver; Rebecca Scherzer; Carmen A Peralta; Phyllis C Tien; Michelle M Estrella; Chirag R Parikh; Anthony W Butch; Kathryn Anastos; Mardge H Cohen; Marek Nowicki; et al. Comparisons of creatinine and cystatin C for detection of kidney disease and prediction of all-cause mortality in HIV-infected women. AIDS (London, England) 2013;27(14):2291-9. 2013 
    7. Matthew C Foy; Michelle M Estrella; Gregory M Lucas; Faryal Tahir; Derek M Fine; Richard D Moore; Mohamed G Atta; Comparison of risk factors and outcomes in HIV immune complex kidney disease and HIV-associated nephropathy. Clinical journal of the American Society of Nephrology : CJASN 2013;8(9):1524-32. 2013 
    8. Michelle M Estrella; Bernard G Jaar; Kerri L Cavanaugh;Chet H Fox; Mark A Parazella; Soman S Sandeep; Emily Howell; Michael V Rocco, Michael J Choi. Perceptions and use of the national kidney foundation KDOQI guidelines: a survey of U.S. renal healthcare providers. BMC Nephrology 2013;Oct 24;14(1):230
    9. Bhavna Bhasin; Michelle M Estrella; Michael J Choi; Online CKD education for medical students, residents, and fellows: training in a new era. Advances in chronic kidney disease 2013;20(4):347-56. 2013 
    10. Michelle M Estrella; Alison G Abraham; Yuezhou Jing; Rulan S Parekh; Phyllis C Tien; Dan Merenstein; Celeste Leigh Pearce; Kathryn Anastos; Mardge H Cohen; Jack A Dehovitz; et al. Antiretroviral-treated HIV-infected women have similar long-term kidney function trajectories as HIV-uninfected women. AIDS research and human retroviruses 2013;29(5):755-60. 2013 
    11. Alison G Abraham; Frank J Palella; Xiuhong Li; Michelle M Estrella; Lawrence A Kingsley; Mallory D Witt; Lisa P Jacobson; The impact of impaired kidney function and HIV infection on the risk of anemia. AIDS research and human retroviruses 2012;28(12):1666-71. 2012 
    12. Mohamed G Atta; Michelle M Estrella; Michael Kuperman; Matthew C Foy; Derek M Fine; Lorraine C Racusen; Gregory M Lucas; George W Nelson; Andrew C Warner; Cheryl A Winkler; et al. HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics. Kidney international 2012;82(3):338-43. 2012 
    13. Teresa K Chen; Michelle M Estrella; Derek M Fine; Predictors of kidney biopsy complication among patients with systemic lupus erythematosus. Lupus 2012;21(8):848-54. 2012 
    14. Rebecca Scherzer; Michelle Estrella; Yongmei Li; Andy I Choi; Steven G Deeks; Carl Grunfeld; Michael G Shlipak; Association of tenofovir exposure with kidney disease risk in HIV infection. AIDS (London, England) 2012;26(7):867-75. 2012 
    15. Derek M Fine; Walter G Wasser; Michelle M Estrella; Mohamed G Atta; Michael Kuperman; Revital Shemer; Arun Rajasekaran; Shay Tzur; Lorraine C Racusen; Karl Skorecki; APOL1 risk variants predict histopathology and progression to ESRD in HIV-related kidney disease. Journal of the American Society of Nephrology : JASN 2012;23(2):343-50. 2012 
    16. Michelle M Estrella; Gregory D Kirk; Shruti H Mehta; Todd T Brown; Derek M Fine; Mohamed G Atta; Gregory M Lucas; Vitamin D deficiency and persistent proteinuria among HIV-infected and uninfected injection drug users. AIDS (London, England) 2012;26(3):295-302. 2012 
    17. Michelle M Estrella; Stephen D Sisson; Jennifer Roth; Michael J Choi; Efficacy of an internet-based tool for improving physician knowledge of chronic kidney disease: an observational study. BMC nephrology 2012;13():126. 2012 
    18. Elizabeth George; Girish N Nadkarni; Michelle M Estrella; Gregory M Lucas; C John Sperati; Mohamed G Atta; Derek M Fine; The impact of hepatitis C coinfection on kidney disease related to human immunodeficiency virus (HIV): a biopsy study. Medicine 2011;90(5):289-95. 2011 
    19. Michelle M Estrella; Rulan S Parekh; Brad C Astor; Robert Bolan; Rhobert W Evans; Frank J Palella; Lisa P Jacobson; Chronic kidney disease and estimates of kidney function in HIV infection: a cross-sectional study in the multicenter AIDS cohort study. Journal of acquired immune deficiency syndromes (1999) 2011;57(5):380-6. 2011
    20. Michelle M Estrella; Mohamed G Atta; Hamid Rabb; Kidney transplantation in HIV-infected patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 2011;58(1):10-2. 2011 
    21. Morgan E Grams; Michelle M Estrella; Josef Coresh; Roy G Brower; Kathleen D Liu; Fluid balance, diuretic use, and mortality in acute kidney injury. Clinical journal of the American Society of Nephrology : CJASN 2011;6(5):966-73. 2011 
    22. Aastha Sethi; Michelle M Estrella; Richard Ugarte; Mohamed G Atta; Kidney function and mortality post-liver transplant in the Model for End-Stage Liver Disease era. International journal of nephrology and renovascular disease 2011;4():139-44. 2011 
    23. Michelle M Estrella; Rulan S Parekh; Alison Abraham; Brad C Astor; Lynda A Szczech; Kathryn Anastos; Jack A Dehovitz; Daniel J Merenstein; C Leigh Pearce; Phyllis C Tien; et al. The impact of kidney function at highly active antiretroviral therapy initiation on mortality in HIV-infected women. Journal of acquired immune deficiency syndromes (1999) 2010;55(2):217-20. 2010 
    24. Michelle M Estrella; Brad C Astor; Anna Köttgen; Elizabeth Selvin; Josef Coresh; Rulan S Parekh; Prevalence of kidney disease in anaemia differs by GFR-estimating method: the Third National Health and Nutrition Examination Survey (1988-94). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(8):2542-8. 2010 
    25. Michelle M Estrella; Chistopher J Sperati; Wen H L Kao; Rulan S Parekh; Genetic epidemiology of chronic kidney disease. Current opinion in nephrology and hypertension 2010;19(3):283-91. 2010 
    26. Michelle M Estrella; Derek M Fine; Screening for chronic kidney disease in HIV-infected patients. Advances in chronic kidney disease 2010;17(1):26-35. 2010 
    27. Michelle Estrella; Derek M Fine; Joel E Gallant; M Hafizur Rahman; Nagapradeep Nagajothi; Lorraine C Racusen; Paul J Scheel; Mohamed G Atta; HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(3):377-80. 2006 
    28. Michelle Estrella; Sara E Cosgrove; Cases from the Osler Medical Service at Johns Hopkins University. Bartonella henselae infection of the liver and spleen. The American journal of medicine 2002;113(4):344-6. 2002 


  • Academic Affiliations & Courses +
  • Activities & Honors +


    2000: Alpha Omega Alpha Medical Honor Society

    2010: National Institutes of Health Loan Repayment Program for Health Disparities Research

    2012: Junior Faculty Excellence in Clinical Research, Department of Medicine, Johns Hopkins University School of Medicine

    Professional Activities

    Multicenter AIDS Cohort Study (
    Womens Interagency HIV Study (
    The North American AIDS Cohort Collaboration on Research and Design(


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    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410-955-0670
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    601 N. Caroline Street
    Baltimore, MD 21287
    Appointment Phone: 410-955-0670
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    • Medicine - Nephrology

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