Skip Navigation
Find a Doctor
 
 
 
 

 

Photo of Dr. Nishant Agrawal

Nishant Agrawal, MD

Associate Professor of Otolaryngology-Head and Neck Surgery

See Research on Pubmed | See Research on Google Scholar

Male
Appointment Phone

443-997-6467

Main Location

Johns Hopkins Outpatient Center

View All Locations
Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Associate Professor of Otolaryngology-Head and Neck Surgery
  • Associate Professor of Oncology

Centers & Institutes

  • Esophageal Cancer Program
  • Head and Neck Cancer Center
  • Sidney Kimmel Comprehensive Cancer Center
  • Upper Aero-digestive Tract Cancer Program

Expertise

Benign Tumors of the Head and Neck, Head and Neck Cancers, Laryngeal Cancer, Oral Cancers, Oral Pathology, Oropharynx Cancers, Otolaryngology, Parathyroid Surgery, Parotid Gland Tumors, Pharynx Cancer, Salivary Gland Disorders, Sinonasal Tumors, Skin Cancer of the Head and Neck, Skull Base Tumors, Thyroid Cancer, Thyroid Masses, Thyroid Nodules, Thyroid Surgery, Tonsil Cancer

Research Interests

Head and Neck Cancer Genetics and Diagnostics; Dr. Agrawal's research is focused on the genetics of head and neck cancer Genetics and the development of diagnostic biomarkers for screening, monitoring and surveillance of head and neck cancer.

Biography

Dr. Agrawal specializes in the treatment of benign and malignant tumors of the head and neck.  He has published widely, including a landmark paper on the genomic landscape of head and neck squamous cell carcinoma.  In addition to the genetics of head and neck tumors, Dr. Agrawal's research is focused on the development of biomarkers for screening, monitoring and surveillance of head and neck tumors.  He serves on several committees of national organizations, including American Head and Neck Society and American Thyroid Association.

Languages

  • English
  • Hindi

Clinical Trial Keywords

  • head and neck cancer, Squamous Cell Carcinoma of Oropharynx

Additional Resources

Additional Resources +
  • Education +

    Training

    • Johns Hopkins University School of Medicine (Baltimore MD) (2001)

    Residencies

    • Johns Hopkins University School of Medicine / Otolaryngology (Baltimore MD) (2007)

    Fellowships

    • Memorial Sloan - Kettering Cancer Center / Oncology (New York NY) (2008)

    Certifications

    • American Board of Otolaryngology / Otolaryngology (2009)
  • Research & Publications +

    Research Summary

    Dr Agrawal’s research is focused on the genetics of head and neck cancer and the development of diagnostic biomarkers for screening, monitoring and surveillance of head and neck cancer.

    Selected Publications View all on PubMed

    Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN.  Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1Science.  2011; 333(6046):  1154-1157.

    Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW.  Mutations in CIC and FUBP1 contribute to human oligodendroglioma.  Science.  2011; 333(6048):  1453-1455.

    Holdhoff M, Schmidt K, Diehl F, Agrawal N, Angenendt P, Romans K, Edelstein D, Torbenson MS, Kinzler K, Vogelstein B, Choti MA, Diaz LA.  Detection of tumor DNA at the margins of colorectal cancer liver metastasis.  Clin Cancer Res.  2011; 17(11):  3551-3557.

    Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Dore S, Synder SH, Sawa A.  GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation.  Neuron.  2009; 63(1):  81-91.

    Diehl F, Schmidt K, Choti M, Romans K, Goodman S, Li M, Thornton K, Agrawal N, Sokoll L, Szabo SA, Kinzler KW, Vogelstein B, Diaz LA.  Circulating tumor DNA to assess tumor dynamics.  Nature Medicine.  2008; 14(9):  985-990.

    Farrag TY, Agrawal N, Sheth S, Bettegowda C, Ewertz M, Kim M, Tufano RP.  An algorithm for safe and effective re-operative thyroid bed surgery for recurrent/persistent papillary thyroid carcinoma.  Head and Neck.  2007; 29(12):  1069-1074.

    Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz LA, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler KW, Vogelstein B, Pomper MG.  Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil.  PNAS.  2005;  102:  1145-1150. 

    Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A.  S-nitrosylated glyceraldehyde-3-phosphate dehydrogenase initiates apoptotic cell death by nuclear translocation following Siah1 binding.  Nature Cell Biology.  2005;  7:  665-674.

    Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A.  p53 mediates cellular dysfunction and behavioral abnormalities in Huntington’s disease.  Neuron.  2005;  47:  29-41.

    Agrawal N, Bettegowda C, Cheong I, Geschwind J, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, Vogelstein B.  Bacteriolytic therapy can generate a potent immune response against experimental tumors.  PNAS.  2004;  101:  15172-15177.

    Clinical Trials

    Treatment De-Intensification for Squamous Cell Carcinoma of the Oropharynx Squamous Cell Carcinoma of Oropharynx (Recruiting)

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Richard Westcott Appleton Scholarship, 2000-2001
    Owsei Temkin Scholarship, 1999-2001
    Johns Hopkins University School of Medicine Scholarship, 1997-1999
    Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
    Henry Rutgers Scholar, 1997
    Betty Falk Yatvin Memorial Award, 1997
    Highest Honors in Biological Sciences, 1997
    Rutgers College Class of 1969 Merit Scholarship, 1996-1997
    Bell Atlantic Scholarship, 1995-1996
    Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
    Waksman Endowment Scholarship, 1994-1995

    Professional Activities

    George T Nager Award for Excellence in Teaching, 2012
    Richard Westcott Appleton Scholarship, 2000-2001
    Owsei Temkin Scholarship, 1999-2001
    Johns Hopkins University School of Medicine Scholarship, 1997-1999
    Marvin Harold Cheiten Award (1st in Class at Rutgers College), 1997
    Henry Rutgers Scholar, 1997
    Betty Falk Yatvin Memorial Award, 1997
    Highest Honors in Biological Sciences, 1997
    Rutgers College Class of 1969 Merit Scholarship, 1996-1997
    Bell Atlantic Scholarship, 1995-1996
    Center for Advanced Biotechnology and Medicine Fellowship, 1995-1996
    Waksman Endowment Scholarship, 1994-1995

  • Videos & Media +

    Videos

    Meet Our Experts: Dr. Nishant Agrawal, Head and Neck Surgeon

    Dr. Nishant Agrawal, Head and Neck Surgeon, specializes in the treatment of benign and malignant tumors of the head and neck including thyroid cancer, skull base tumors and salivary gland tumors.

    Recent News Articles & Media Coverage

    Breakthrough in cancer research at Johns Hopkins' Ludwig Center, WBFF-TV (02/05/2014)

  • Events +
  • Contact & Locations +

    Locations

    Johns Hopkins Outpatient Center
    601 N. Caroline Street
    Baltimore, MD 21287
    Phone: 410-502-9827
    Appointment Phone: 443-997-6467
    Fax: 410-955-0035
    Location Map
    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-502-9827
    Appointment Phone: 443-997-6467
    Fax: 410-955-0035
    Location Map

    Department/Division

    • Otolaryngology - Head and Neck Surgery - Division of Head and Neck Surgery
    • Otolaryngology - Head and Neck Surgery - Division of Thyroid and Parathyroid

Is This You? Edit Profile

 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.