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Photo of Dr. Marc Kenneth Halushka, MD PhD

Marc Kenneth Halushka, MD PhD

Director, Oncology Tissue Services (formerly the Tissue Microarray Core)
Associate Professor of Pathology

See Research on Pubmed

Male
Appointment Phone

410-502-7261

Main Location

The Johns Hopkins Hospital

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Out-of-State & International Patients +
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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Oncology Tissue Services (formerly the Tissue Microarray Core)
  • Associate Professor of Pathology
  • Associate Professor of Oncology

Centers & Institutes

  • Comprehensive Transplant Center

Expertise

Cardiovascular Diseases, Pathology, Transplant Pathology

Research Interests

Cardiac transplantation; Diabetic vascular disease; MicroRNA expression; Endothelial cell biology; Sudden cardiac death

Biography

Dr. Marc Halushka is an associate professor of pathology and oncology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include cardiovascular pathology, autopsy pathology, and transplant pathology. He is a world-renown expert on cardiovascular tissue microarrays. Dr. Halushka is director of Johns Hopkins University Oncology Tissue Services (formerly the Tissue Microarray Core).

He earned his M.D. and Ph.D. from Case Western Reserve University School of Medicine. He completed both a residency and fellowship in pathology at the Johns Hopkins School of Medicine.

Dr. Halushka''s research interests include diabetic vascular disease, microRNA expression, endothelial cell biology, sudden cardiac death and cardiac transplantation.

In addition to his many roles at Johns Hopkins University School of Medicine, Dr. Halushka is an adjunct associate professor at Perdana University Graduate School of Medicine in Malaysia.

Dr. Halushka was honored with a 2013 Johns Hopkins University School of Medicine International Medical Education Award. He is a member of the American Society of Human Genetics, the American Diabetes Association, the International Society of Heart and Lung Transplantation, and the Society of Cardiovascular Pathology.

Languages

  • English

Memberships

American Society of Human Genetics
American Diabetes Association
International Society of Heart and Lung Transplantation
Society of Cardiovascular Pathology

Additional Resources

Additional Resources +
  • Education +

    Training

    • St. Vincent Charity Medical Center (Cleveland OH) (2001)

    Residencies

    • Johns Hopkins University School of Medicine / Pathology (Baltimore MD) (2004)

    Fellowships

    • Johns Hopkins University School of Medicine / Pathology (Baltimore MD) (2004)

    Certifications

    • American Board of Pathology / Anatomic Pathology (2005)
  • Research & Publications +

    Research Summary

    Dr. Halushka’s laboratory is currently working to identify biomarkers of sudden cardiac death and expression patterns of microRNAs in tissues and cells. MicroRNAs are key post-translational regulators of genes. He is interested in determining how microRNAs are altered in human diseases.

    His laboratory is also involved in a number of collaborative projects relating to cardiovascular diseases such as sudden cardiac death, cardiac citrullination and neonatal lupus.

    Selected Publications View all on PubMed

    1. Sharma K, Orbai AM, Desai D, Cingolani OH, Halushka MK, Christopher-Stine L, Mammen AL, Wu KC, Zakaria S. “Brief Report: Antisynthetase Syndrome-Associated Myocarditis.” J Card Fail. 2014 Jul 29. pii: S1071-9164(14)00685-X.
    2. Kent OA, McCall MN, Cornish TC, Halushka MK. “Lessons from miR-143/145: the importance of cell-type localization of miRNAs.” Nucleic Acids Res. 2014 Aug 1;42(12):7528-38. doi: 10.1093/nar/gku461. Epub 2014 May 29.
    3. Kim MS, Pinto SM, Getnet D, Nirujogi RS, Manda SS, Chaerkady R, Madugundu AK, Kelkar DS, Isserlin R, Jain S, Thomas JK, Muthusamy B, Leal-Rojas P, Kumar P, Sahasrabuddhe NA, Balakrishnan L, Advani J, George B, Renuse S, Selvan LD, Patil AH, Nanjappa V, Radhakrishnan A, Prasad S, Subbannayya T, Raju R, Kumar M, Sreenivasamurthy SK, Marimuthu A, Sathe GJ, Chavan S, Datta KK, Subbannayya Y, Sahu A, Yelamanchi SD, Jayaram S, Rajagopalan P, Sharma J, Murthy KR, Syed N, Goel R, Khan AA, Ahmad S, Dey G, Mudgal K, Chatterjee A, Huang TC, Zhong J, Wu X, Shaw PG, Freed D, Zahari MS, Mukherjee KK, Shankar S, Mahadevan A, Lam H, Mitchell CJ, Shankar SK, Satishchandra P, Schroeder JT, Sirdeshmukh R, Maitra A, Leach SD, Drake CG, Halushka MK, Prasad TS, Hruban RH, Kerr CL, Bader GD, Iacobuzio-Donahue CA, Gowda H, Pandey A. “A draft map of the human proteome.” Nature. 2014 May 29;509(7502):575-81. doi: 10.1038/nature13302.
    4. Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T. “Polycystin signaling is required for directed endothelial cell migration and lymphatic development.” Cell Rep. 2014 May 8;7(3):634-44. doi: 10.1016/j.celrep.2014.03.064. Epub 2014 Apr 24.
    5. Steppan J, Sikka G, Jandu S, Barodka V, Halushka MK, Flavahan NA, Belkin AM, Nyhan D, Butlin M, Avolio A, Berkowitz DE, Santhanam L. “Exercise, vascular stiffness, and tissue transglutaminase.” J Am Heart Assoc. 2014 Apr 10;3(2):e000599. doi: 10.1161/JAHA.113.000599.
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Johns Hopkins University School of Medicine International Medical Education Award, 2013

    Johns Hopkins University School of Medicine Basic Sciences Faculty Teaching Award, 2011

  • Videos & Media +
  • Events +
  • Contact & Locations +

    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Ross Building Room 632L
    Baltimore, MD 21287
    Phone: 410-502-7261
    Appointment Phone: 410-502-7261
    Location Map

    Department/Division

    • Pathology

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