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Laura Kathleen Hummers, M.D.
Clinical Director, Division of Rheumatology
Associate Professor of Medicine
Expertise: Rheumatology, Scleroderma
Research Interests: Scleromyxedema; Scleroderma
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Johns Hopkins Bayview Medical Center
Appointment Phone: 443-997-1552
5501 Hopkins Bayview Circle
Asthma and Allergy Center 1B.1
Baltimore, MD 21224 map
Contact for Research Inquiries
5200 Eastern Avenue
MFL Center Tower, Suite 4000
Baltimore, MD 21224 map
- M.D.: University of Rochester, Rochester, NY
- Sc.M. Clinical Investigation: Johns Hopkins Bloomberg School of Public Health
- Post-doctoral Fellowship: Johns Hopkins University, Baltimore, MD
- Internship and Residency: Thomas Jefferson University, Philadelphia, PA.
Laura Hummers is an Associate Professor of Medicine in the Division of Rheumatology. She graduated from the University of Rochester School of Medicine and trained in internal medicine at Thomas Jefferson University. She then pursued her rheumatology fellowship at Johns Hopkins University and has since been on the faculty working at the Johns Hopkins Scleroderma Center since 2003 where she has been Co-Director of the Center along with Fredrick Wigley. She received her ScM degree through the Graduate Training Program in Clinical Investigation from the Bloomberg School of Public Health in 2010. Dr. Hummers also serves as Clinical Director for the Division of Rheumatology.
Dr. Hummers actively participates in a number of clinical trials and clinical investigations at the Scleroderma Center and has a particular interest in predictors of outcomes in scleroderma. She actively manages a large patient practice focused exclusively on scleroderma and related conditions at Johns Hopkins and actively helps to manage the Johns Hopkins Scleroderma Center longitudinal database..
Presently, Dr. Hummers has established a prospective cohort of 300 patients with scleroderma being followed to identify incident vascular outcomes in the hopes of identifying new biomarkers for disease development and progression. These efforts have been supported by a K23 grant from NIH/NIAMS and as part of a SCCOR grant in pulmonary hypertension. She actively mentors several other faculty members and fellows in the division in investigations in systemic sclerosis. She also has specific expertise in other scleroderma-like conditions such as scleromyxedema, scleredema and eosinophilic fasciitis.
- Clinical Director, Division of Rheumatology
- Co-Director, Johns Hopkins Scleroderma Center
- Associate Professor of Medicine
Centers & Institutes
- MD, University of Rochester School of Medicine and Dentistry (1997)
- Thomas Jefferson University Hospital / Internal Medicine (2000)
- Johns Hopkins University School of Medicine / Rheumatology (2003)
- American Board of Internal Medicine / Rheumatology (2003)
Research & Publications
Clinical Trial KeywordsScleroderma, Scleromyxedema
Selected PublicationsView all on Pubmed
Chung L, Domsic RT, Lingala B, Alkassab F, Bolster M, Csuka ME, Derk C, Fischer A, Frech T, Furst DE, Gomberg-Maitland M, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TA Jr, Molitor JA, Preston IR, Schiopu E, Shapiro L, Silver R, Simms R, Varga J, Gordon JK, Steen VD. Survival and predictors of mortality in systemic sclerosis associated pulmonary arterial hypertension: Outcomes from the PHAROS registry. Arthritis Care Res (Hoboken). 2013 Aug 27. doi: 10.1002/acr.22121. [Epub ahead of print] PMID: 23983198
Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369
Gelber AC, Manno RL, Shah AA, Woods A, Le EN, Boin F, Hummers LK, Wigley FM. Race and association with disease manifestations and mortality in scleroderma: a 20-year experience at the Johns Hopkins Scleroderma Center and review of the literature. Medicine (Baltimore). 2013 Jul;92(4):191-205. doi: 10.1097/MD.0b013e31829be125. Review. PMID: 23793108
Shah AA, Schiopu E, Hummers LK, Wade M, Phillips K, Anderson C, Wise R, Boin F, Seibold JR, Wigley F, Rollins KD. Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion. Arthritis Res Ther. 2013 Apr 18;15(2):R54. [Epub ahead of print] PMID: 23597147
Dezern AE, Styler MJ, Drachman DB, Hummers LK, Jones RJ, Brodsky RA. Repeated treatment with high dose cyclophosphamide for severe autoimmune diseases. Am J Blood Res. 2013;3(1):84-90. Epub 2013 Jan 17. PMID: 23358715
Hummers LK, Dugowson CE, Dechow FJ, Wise RA, Gregory J, Michalek J, Yenokyan G, McGready J, Wigley FM. A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon. Ann Rheum Dis. 2013 Dec 1;72(12):1962-7. doi: 10.1136/annrheumdis-2012-201536. Epub 2012 Dec 25. PMID: 23268365
McMahan ZH, Hummers LK. Systemic sclerosis--challenges for clinical practice. Nat Rev Rheumatol. 2013 Feb;9(2):90-100. doi: 10.1038/nrrheum.2012.191. Epub 2012 Nov 13. Review. PMID: 23147899
Shah AA, Chung SE, Wigley FM, Wise RA, Hummers LK. Changes in estimated right ventricular systolic pressure predict mortality and pulmonary hypertension in a cohort of scleroderma patients. Ann Rheum Dis. 2013 Jul;72(7):1136-40. doi: 10.1136/annrheumdis-2012-201861. Epub 2012 Aug 11. PMID: 22887850
Cheadle C, Berger AE, Mathai SC, Grigoryev DN, Watkins TN, Sugawara Y, Barkataki S, Fan J, Boorgula M, Hummers L, Zaiman AL, Girgis R, McDevitt MA, Johns RA, Wigley F, Barnes KC, Hassoun PM. Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients. PLoS One. 2012;7(4):e34951. doi: 10.1371/journal.pone.0034951. Epub 2012 Apr 24. PMID: 22545094
Sharif R, Mayes MD, Tan FK, Gorlova OY, Hummers LK, Shah AA, Furst DE, Khanna D, Martin J, Bossini-Castillo L, Gonzalez EB, Ying J, Draeger HT, Agarwal SK, Reveille JD, Arnett FC, Wigley FM, Assassi S. IRF5 polymorphism predicts prognosis in patients with systemic sclerosis. Ann Rheum Dis. 2012 Jul;71(7):1197-202. doi: 10.1136/annrheumdis-2011-200901. Epub 2012 Mar 22. PMID: 22440820