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John O'Brien Clarke, III, M.D.

Photo of Dr. John O'Brien Clarke, III, M.D.


Expertise: Achalasia, Barrett's Esophagus, Burping, Belching, Clinical Gastroenterology, Constipation, Digestive Diseases, Eosinophilic Esophagitis, Esophageal Diseases, Gastroenterology, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Heartburn, Hiccups, Hoarseness, Motility Disorders, Nausea, Neurogastroenterology, Rectal Problem, Reflux and Burning, Stomach Ulcer, Swallowing Disorders, Vomiting more

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The Johns Hopkins Hospital
Appointment Phone: 410-933-7495

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-9696

Johns Hopkins Medicine - Green Spring Station
Appointment Phone: 410-828-3585

Green Spring Station
2360 W. Joppa Road
Suite 200
Lutherville, MD 21093 map
Phone: 410-828-3585


Dr. John OBrien Clarke is an Assistant Professor of Medicine in the Division of Gastroenterology at The Johns Hopkins Hospital. His clinical and research interests include dysphagia (swallowing disorders), gastroesophageal reflux disease, esophageal motility, eosinophilic esophagitis, gastroparesis and other gastrointestinal motility disorders.

He completed undergraduate training at Brown University in Providence, Rhode Island and received his medical degree (M.D.) from Columbia University in New York City. He completed internship and residency in Internal Medicine at The Johns Hopkins Hospital. He then worked for 2-years as a Hospitalist before completing Gastroenterology Fellowship at The Johns Hopkins Hospital.

In addition to routine fellowship training, Dr. Clarke also worked for several months with Dr. Peter Kahrilas at Northwestern University in Chicago, Illinois, pursuing advanced training in the field of esophageal motility. Dr. Clarke is currently the Director of Esophageal Motility at The Johns Hopkins Hospital. more



  • MD, Columbia University College of Physicians and Surgeons (1999)


  • Johns Hopkins University School of Medicine / Medicine (2002)


  • Johns Hopkins University School of Medicine / Gastroenterology (2007)

Board Certifications

  • American Board of Internal Medicine / Gastroenterology (2007)
  • American Board of Internal Medicine / Internal Medicine (2002, 2012)
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