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Photo of Dr. Jonathan Brett Orens, MD

Jonathan Brett Orens, MD

Interim Director, Division of Pulmonary and Critical Care Medicine
Professor of Medicine
Male
Appointment Phone

410-550-5864

Main Location

The Johns Hopkins Hospital

View All Locations
Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Interim Director, Division of Pulmonary and Critical Care Medicine
  • Medical Director, Lung Transplantation Program
  • Professor of Medicine

Centers & Institutes

  • Comprehensive Transplant Center

Expertise

Critical Care Medicine, Lung Transplant, Pulmonary Disease and Critical Care Medicine, Pulmonary Diseases

Research Interests

Ischemic reperfusion injury ("primary graft dysfunction"); Chronic allograft rejection; Clinical outcomes of lung transplantation

Languages

  • English

Additional Resources

Additional Resources +
  • Education +

    Training

    • University of Maryland School of Medicine (Baltimore MD) (1987)

    Residencies

    • University of Maryland Medical System / Internal Medicine (Baltimore MD) (1991)

    Fellowships

    • University of Michigan Hospitals / Pulmonary and Critical Care Medicine (Ann Arbor MI) (1994)

    Certifications

    • American Board of Internal Medicine / Internal Medicine (2011)
    • American Board of Internal Medicine / Critical Care Medicine (2000)
    • American Board of Internal Medicine / Pulmonary Disease (2000)
  • Research & Publications +

    Selected Publications

    1. Diamond JM, Akimova T, Kazi A, Shah RJ, Cantu E, Feng R, Levine MH, Kawut SM, Meyer NJ, Lee JC, Hancock WW, Aplenc R, Ware LB, Palmer SM, Bhorade S, Lama VN, Weinacker A, Orens J, Wille K, Crespo M, Lederer DJ, Arcasoy S, Demissie E, Christie JD; for the Lung Transplant Outcomes Group. Genetic Variation in Prostaglandin E2 Pathway is Associated with Primary Graft Dysfunction. Am J Respir Crit Care Med. 2014 Jan 27. [Epub ahead of print] PMID: 24467603
    2. Shah RJ, Wickersham N, Lederer DJ, Palmer SM, Cantu E, Diamond JM, Kawut SM, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Shah P, Arcasoy S, Wilkes DS, Christie JD, Ware LB; Lung Transplant Outcomes Group. Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation. Am J Transplant. 2014 Feb;14(2):446-52. doi: 10.1111/ajt.12541. Epub 2014 Jan 8. PMID: 24400993
    3. Eberlein M, Reed RM, Maidaa M, Bolukbas S, Arnaoutakis GJ, Orens JB, Brower RG, Merlo CA, Hunsicker LG. Donor-recipient size matching and survival after lung transplantation. A cohort study. Ann Am Thorac Soc. 2013 Oct;10(5):418-25. doi: 10.1513/AnnalsATS.201301-008OC.
      PMID: 23988005 [PubMed - in process]
    4. Miller HL, Shah PD, Orens JB, McDyer JF. Prevention of airway allograft tolerance by polyinosinic:polycytidylic acid requires type I interferon responsiveness for mouse airway obliteration. J Heart Lung Transplant. 2013 Sep;32(9):914-24. doi: 10.1016/j.healun.2013.06.017. PMID: 23953819 [PubMed - in process]
    5. Shah P, Orens JB. Impact of nutritional state on lung transplant outcomes: the weight of the evidence. J Heart Lung Transplant. 2013 Aug;32(8):755-6. doi: 10.1016/j.healun.2013.06.001. PMID: 23856213 
    6. Eberlein M, Reed RM, Bolukbas S, Parekh KR, Arnaoutakis GJ, Orens JB, Brower RG, Shah AS, Hunsicker L, Merlo CA. Lung size mismatch and survival after single and bilateral lung transplantation. Ann Thorac Surg. 2013 Aug;96(2):457-63. doi: 10.1016/j.athoracsur.2013.04.064. Epub 2013 Jun 26. PMID: 23809729 
    7. Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Localio AR, Demissie E, Kawut SM, Bellamy SL, Christie JD.Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest. 2013 Aug;144(2):616-22. doi: 10.1378/chest.12-1480. PMID: 23429890
    8. Yarmus L, Akulian J, Gilbert C, Illei P, Shah P, Merlo C, Orens J, Feller-Kopman D. Cryoprobe transbronchial lung biopsy in patients after lung transplantation: a pilot safety study. Chest. 2013 Mar;143(3):621-6. PMID: 23328889 
    9. Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy SL, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade SM, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD; Lung Transplant Outcomes Group. Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med. 2013 Mar 1;187(5):527-34. doi: 10.1164/rccm.201210-1865OC. Epub 2013 Jan 10. PMID: 23306540 
    10. Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy SL, Palmer SM, Lama VN, Bhorade SM, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Arcasoy S, Wilkes DS, Ware LB, Christie JD; Lung Transplant Outcomes Group. Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation. PLoS One. 2012;7(12):e51932. doi: 10.1371/journal.pone.0051932. Epub 2012 Dec 19. PMID: 23284823
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +
  • Events +
  • Contact & Locations +

    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    1830 East Monument Street
    5th floor
    Baltimore, MD 21287
    Phone: 410-955-3467
    Appointment Phone: 410-550-5864
    Location Map
    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Baltimore, MD 21224
    Appointment Phone: 410-550-5864 (PULM); 410-550-5633 (INTERN)
    Location Map

    Department/Division

    • Medicine - Pulmonary and Critical Care Medicine

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