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Una D McCann, MD

Associate Program Director JHBMC GCRC
Professor of Psychiatry and Behavioral Sciences
Female
Appointment Phone

410-550-0018

Main Location

Johns Hopkins Bayview Medical Center

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Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Associate Program Director JHBMC GCRC
  • Director, Anxiety Disorders Program
  • Professor of Psychiatry and Behavioral Sciences
  • Professor of Neurology

Centers & Institutes

  • Anxiety Disorders Program
  • Behavioral Pharmacology Research Unit
  • Heart and Vascular Institute
  • Women's Cardiovascular Health Center

Expertise

Adult Psychiatry

Languages

  • English
  • Spanish
Additional Resources +
  • Education +

    Training

    • Duke University School of Medicine ( Durham NC ) (1984)

    Residencies

    • Stanford University School of Medicine/Psychiatry ( Stanford CA ) (1988)

    Fellowships

    • Stanford University School of Medicine/Psychiatry ( Stanford CA ) (1988)

    Certifications

    • Psychosomatic Medicine, American Board of Psychiatry & Neurology (2008)
    • Psychiatry, American Board of Psychiatry & Neurology (1990)
  • Research & Publications +

    Research Summary

    My two active areas of research are in the areas of amphetamine-induced monoamine neurotoxicity (i.e., MDMA, Methamphetamine, ephedrine or amphetamine-induced monoaminergic neurotoxicity), and the neurobiology of anxiety disorders. Methods used in both research spheres include neuropharmacology, PET, MRI, fMRI, polysomnography, pharmacological challenge, and neuropsychiatric assessment. Studies of amphetamine neurotoxicity also include preclinical studies using microarrays, cell culture, rodents and primates.

    Selected Publications

    1. McCann UD, Szabo Z, Scheffel U, Matthews WB, Dannals RF, Ravert HT, Musachio JL, Mertl MM, Ricaurte GA. Positron Emission Tomographic evidence of toxic effect of MDMA (AEcstasy@) on brain serotonin neurons in humans beings, The Lancet, 1998; 352:1433-1437.
    2. McCann UD, Wong DF, Villemagne V, Dannals RF, Ricaurte GA. Brain dopamine neurotoxicity in abstinent methamphetamine and methcathinone users: Evidence from PET studies with [11C]WIN- 35,428, Journal of Neuroscience 1998;18(20):8417-8422.
    3. McCann UD, Mertl MM, Eligulashvili V, Ricaurte GA. Cognitive performance in () 3,4- methylenedioxymethamphetamine (MDMA, "ecstasy") users: A controlled study, Psychopharmacology, 1999; 143:417-425
    4. McCann UD, Slate SO, Geraci M, Roscow-Terrill D, and Uhde TW. A comparison of the effects of intravenous pentagastrin in patients with social phobia, panic disorder, and healthy volunteers, Neuropsychopharmacology, 1997;16(3):229-237.
    5. Geraci M, Anderson TS, Slate-Cothren S, Post RM, McCann UD. Pentagastrin-induced sleep panic attacks: Panic in the absence of elevated baseline arousal. Biological Psychiatry, 2002;52(12):1183-9.
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +

    Recent News Articles & Media Coverage

    Hopkins Brain Wise Newsletter articles about Dr. McCann's work:

    Translations: Model of a Muddle

    Look What They’ve Done to Their Brains

  • Upcoming Events +
  • Contact & Locations +

    Locations

    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Baltimore, MD 21224
    Appointment Phone: 410-550-0018
    Location Map
    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410-955-5104
    Location Map
    Johns Hopkins Bayview Medical Center
    5501 Hopkins Bayview Circle
    Asthma and Allergy Center
    Baltimore, MD 21224
    Appointment Phone: 410-550-6337
    Location Map

    Department/Division

    • Psychiatry and Behavioral Sciences

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