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Una Deirdre McCann, M.D.

Associate Program Director JHBMC GCRC
Professor of Psychiatry and Behavioral Sciences


Appointment Phone


Main Location

Johns Hopkins Bayview Medical Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Associate Program Director JHBMC GCRC
  • Director, Anxiety Disorders Program
  • Professor of Psychiatry and Behavioral Sciences
  • Professor of Neurology

Centers & Institutes



Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-6337

4940 Eastern Avenue
Baltimore, MD 21224 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-5104

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-6337

5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map


Adult Psychiatry

    Additional Information

  • Education +
    • B.A., Princeton University (New Jersey) (1980)
    • M.D., Duke University (North Carolina) (1984)
  • Research & Publications +

    Research Summary

    My two active areas of research are in the areas of amphetamine-induced monoamine neurotoxicity (i.e., MDMA, Methamphetamine, ephedrine or amphetamine-induced monoaminergic neurotoxicity), and the neurobiology of anxiety disorders. Methods used in both research spheres include neuropharmacology, PET, MRI, fMRI, polysomnography, pharmacological challenge, and neuropsychiatric assessment. Studies of amphetamine neurotoxicity also include preclinical studies using microarrays, cell culture, rodents and primates.

    Selected Publications

    1. McCann UD, Szabo Z, Scheffel U, Matthews WB, Dannals RF, Ravert HT, Musachio JL, Mertl MM, Ricaurte GA. Positron Emission Tomographic evidence of toxic effect of MDMA (AEcstasy@) on brain serotonin neurons in humans beings, The Lancet, 1998; 352:1433-1437.
    2. McCann UD, Wong DF, Villemagne V, Dannals RF, Ricaurte GA. Brain dopamine neurotoxicity in abstinent methamphetamine and methcathinone users: Evidence from PET studies with [11C]WIN- 35,428, Journal of Neuroscience 1998;18(20):8417-8422.
    3. McCann UD, Mertl MM, Eligulashvili V, Ricaurte GA. Cognitive performance in () 3,4- methylenedioxymethamphetamine (MDMA, "ecstasy") users: A controlled study, Psychopharmacology, 1999; 143:417-425
    4. McCann UD, Slate SO, Geraci M, Roscow-Terrill D, and Uhde TW. A comparison of the effects of intravenous pentagastrin in patients with social phobia, panic disorder, and healthy volunteers, Neuropsychopharmacology, 1997;16(3):229-237.
    5. Geraci M, Anderson TS, Slate-Cothren S, Post RM, McCann UD. Pentagastrin-induced sleep panic attacks: Panic in the absence of elevated baseline arousal. Biological Psychiatry, 2002;52(12):1183-9.
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +

    Recent News Articles & Media Coverage

    Hopkins Brain Wise Newsletter articles about Dr. McCann's work:

    Translations: Model of a Muddle

    Look What They’ve Done to Their Brains

Is This You? Edit Profile

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