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Ravit Boger, MD

Associate Professor of Pediatrics
Appointment Phone


Main Location

Johns Hopkins Pediatric Specialty Clinic

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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Associate Professor of Pediatrics
  • Associate Professor of Oncology

Centers & Institutes

  • Children's Center


Pediatric Infectious Disease, Pediatric Infectious Diseases

Research Interests

Congneital Cytomegalovirus infection; Strain diversity; Genotyping; Viral load


Dr. Ravit Boger is an associate professor of pediatrics and oncology at the Johns Hopkins University School of Medicine. Her area of clinical expertise is pediatric infectious diseases.

She is known for her research on congenital cytomegalovirus (CMV) infection. Her lab was among the first in this country to characterize CMV genes, and they recently identified a protein that regulates the body’s immune response to CMV.

Dr. Boger earned her medical degree from the Sackler School of Medicine at Tel-Aviv University. Following an internship at the Rabin Medical Center in Petah-Tivah, Israel, and service as a physician in the Israel Defense Forces, she completed a residency in pediatrics at Dana Children’s Hospital in Tel-Aviv. Dr. Boger performed her fellowship in pediatric infectious diseases at Johns Hopkins University School of Medicine. She joined the Johns Hopkins faculty in 2001.

Her research interests include CMV infection, with a particular focus of identifying and developing novel anti-CMV compounds. Her studies also focus on understanding the mechanisms of CMV inhibition by newly identified anti-CMV compounds.

She is a member of the American Society of Pediatric Infectious Diseases and the Infectious Diseases Society of America.


  • English
  • Hebrew
  • French


American Society of Pediatric Infectious Diseases

Infectious Diseases Society of America

Clinical Trial Keywords

  • CASG

Additional Resources

Additional Resources +
  • Education +


    • Tel Aviv University (69 978 Tel Aviv) (1988)


    • Dana Children's Hospital / Pediatrics (Tel Aviv) (1988)


    • Johns Hopkins University School of Medicine / Pediatric Infectious Diseases (Baltimore MD ) (1988)
  • Research & Publications +

    Research Summary

    Dr. Ravit's research focuses on characterizing CMV strains and understanding their impact on pathogenesis and outcome of congenital CMV infection. In addition, her laboratory is actively involved in research of novel compounds for CMV therapy.

    Her work is funded by the NIH and has been published in several research journals. Dr. Boger is a member of the collaborative anti-viral study group and is a site principal investigator for a clinical trial of valganciclovir in congenital CMV infection.

    Selected Publications

    1. Kapoor A, Forman M, Arav-Boger R. “Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication.” PLoS One. 2014 Mar 26;9(3):e92704. doi: 10.1371/journal.pone.0092704. eCollection 2014.
    2. Cai H, Kapoor A, He R, Venkatadri R, Forman M, Posner GH, Arav-Boger R. “In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action.” Antimicrob Agents Chemother. 2014 Feb;58(2):986-94. doi: 10.1128/AAC.01972-13. Epub 2013 Nov 25.
    3. He R, Forman M, Mott BT, Venkatadri R, Posner GH, Arav-Boger R. “Unique and highly selective anticytomegalovirus activities of artemisinin-derived dimer diphenyl phosphate stem from combination of dimer unit and a diphenyl phosphate moiety.” Antimicrob Agents Chemother. 2013 Sep;57(9):4208-14. doi: 10.1128/AAC.00893-13. Epub 2013 Jun 17.
    4. Mott BT, He R, Chen X, Fox JM, Civin CI, Arav-Boger R, Posner GH. “Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: a structure-activity study.” Bioorg Med Chem. 2013 Jul 1;21(13):3702-7. doi: 10.1016/j.bmc.2013.04.027. Epub 2013 Apr 22.
    5. Kapoor A, He R, Venkatadri R, Forman M, Arav-Boger R. “WNT modulating agents inhibit human cytomegalovirus replication.” Antimicrob Agents Chemother. 2013 Jun;57(6):2761-7. doi: 10.1128/AAC.00029-13. Epub 2013 Apr 9.


    Dr. Boger's laboratory is working on the identification and development of novel anti-Cytomegalovirus compounds. Their studies also focus on understanding the mechanisms of CMV inhibition by newly identified anti-CMV compounds.

    Main research topics in the laboratory include:

    • CMV inhibition by artemisinin-derived dimers
    • Models of anti-viral combination therapy
    • Role of WNT pathway in CMV replication
    • CMV recognition by NOD2

    Clinical Trials

    Evaluation of the PK and PD of Ganciclovir in Premature Infants Receiving Treatment for CMV Infection (Gan Premie)

    Congenital CMV and Hearing Loss in Children up to 4 Years of Age: Treating with Valganciclovir Therapy

  • Academic Affiliations & Courses +
  • Activities & Honors +


    Recognition, Thomas Wilson Foundation, 2005 - 2006

    Clinician Scientist Award, Johns Hopkins University School of Medicine, 2003 - 2005

    Recognition, United Cerebral Palsy, 2003 - 2005

  • Videos & Media +
  • Events +
  • Contact & Locations +


    Johns Hopkins Pediatric Specialty Clinic
    200 N. Wolfe Street
    Rubenstein Child Health
    Baltimore, MD 21287
    Phone: 410-614-3917
    Appointment Phone: 410-614-3917
    Fax: 410-614-1491
    Location Map


    • Pediatrics - Infectious Diseases

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