Diabetes, General Internal Medicine, Nonalcoholic Fatty Liver Disease, Obesity, Primary Care
Dr. Clark has devoted her career to studying the epidemiology and treatment of obesity and its consequences, especially type 2 diabetes and nonalcoholic fatty liver disease. She has been a key investigator in several multi-center, landmark trials including the Diabetes Prevention Program trial (DPP), the Practice-based Opportunities for Weight Reduction trial (POWER), and the Action for Health in Diabetes trial (Look AHEAD). She is currently conducting a trial to determine the comparative effectiveness and mechanisms of diabetes improvement following weight loss achieved by 3 methods: lifestyle change, gastric banding surgery, and gastric bypass surgery. In addition to her clinical trial work, she has conducted epidemiologic and translational studies, qualitative studies, systematic reviews and health services research all aimed at improving our understanding of obesity and its consequences, in order to better prevent, diagnose and treat these conditions and improve the health of individual patients as well as the public. Dr. Clark is a practicing general internist and is actively involved in medical education.