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Photo of Dr. Alexandra Valsamakis, M.D., Ph.D.

Alexandra Valsamakis, M.D., Ph.D.

Director, Clinical Virology and Molecular Microbiology
Associate Professor of Pathology

Female

Appointment Phone

410-955-2660

Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Clinical Virology and Molecular Microbiology
  • Associate Professor of Pathology

Departments

Locations

The Johns Hopkins Hospital

Appointment Phone: 410-955-2660

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

The Johns Hopkins Hospital

600 N. Wolfe Street
Carnegie 446D1
Baltimore, MD 21287 map

Expertise

Pathology

Research Interests

Hepatitis C and B infections; Infectious diseases

Biography

Dr. Alexandra Valsamakis is an associate professor of pathology at the Johns Hopkins University School of Medicine. She holds joint secondary appointments in molecular medicine and immunology, and serves as director of Clinical Virology and Molecular Microbiology.

She received an M.D. from University of Pennsylvania and a Ph.D. in microbiology from the Medical College of Pennsylvania. After a residency in pathology at the University of California-San Diego, she completed two fellowships at Johns Hopkins, one in medical microbiology and a second in microbiology and immunology.

Dr. Valsamakis’ research focuses on the detection, identification, and therapeutic monitoring of infectious diseases, particularly viral infections.

She serves on the editorial boards of Diagnostic Microbiology and Infectious Diseases and Manual of Clinical Microbiology, and is an ad hoc reviewer for Clinical and Diagnostic Laboratory Immunology, Journal of Clinical Microbiology, Journal of Molecular Diagnostics and Journal of Viral Hepatitis. She is a member of the American Society for Microbiology, the Association for Molecular Pathology, the Infectious Disease Society of America and the Pan-American Society for Clinical Virology. She is certified in clinical pathology by the American Board of Pathology.

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    Additional Information

  • Education +

    Degrees

    • Hospital of the University of Pennsylvania / MD (1992)

    Residencies

    • University of California / Pathology (1994)

    Fellowships

    • Johns Hopkins Bloomberg School of Public Health / Microbiology and Immunology (1997)
    • Johns Hopkins University School of Medicine / Medical Microbiology (1998)

    Certifications

    • American Board of Pathology / Clinical Pathology (1996)
  • Research & Publications +

    Research Summary

    Dr. Valsamakis’ research focuses on the detection, identification, and therapeutic monitoring of infectious diseases, particularly viral infections. Her current work entails:

    1. Improving molecular assays that are critical for the management of hepatitis C and hepatitis B infections
    2. Devising quantitative assays for viral infections and studying their clinical utility particularly in immunocompromised patients
    3. Investigation of the performance and utility of automated nucleic acid preparation instrumentation in the clinical laboratory. Her lab uses a variety of conventional (cell culture, antigen detection) and molecular techniques (nucleic acid amplification, primarily PCR and real time PCR).

    Selected Publications

    1. Forman MS, Valsamakis A. "Verification of an assay for quantification of HCV RNA using an analyte specific reagent and two different extraction methods." J. Clin. Micro. 2004;42:3581-8.
    2. Forman MS, Valsamakis A. "Increased sensitivity of the Roche COBAS AMPLICOR HCV test v.2.0, using modified extraction techniques." J. Molec. Diag. 2004;6:225-30.
    3. Knepp JH, Geahr MA, Forman MS, Valsamakis A. "Comparison of Automated and Manual Nucleic Acid Extraction Methods for the Detection of Enterovirus RNA." J. Clin. Microbiol. 2003;41: 3532-3536.
    4. Dumler JS, Valsamakis, A. "Molecular diagnostics of infectious diseases: complementary tools for a new era of clinical microbiology." Am. J. Clin. Path. 1999;112: S33-S39.
  • Academic Affiliations & Courses +

    Graduate Program Affiliation

    Graduate Program in Molecular Microbiology and Immunology

  • Activities & Honors +

    Memberships

    • American Society for Microbiology
      President, Maryland Branch, 2002 - 2004
    • Association for Molecular Pathology
      Chair-Elect, Infectious Diseases Subdivision
    • Infectious Disease Society of America
    • Pan-American Society for Clinical Virology

    Professional Activities

    • Ad hoc reviewer, Clinical and Diagnostic Laboratory Immunology
    • Ad hoc reviewer, Journal of Clinical Microbiology
    • Ad hoc reviewer, Journal of Molecular Diagnostics
    • Ad hoc reviewer, Journal of Viral Hepatitis
    • Editorial board, Diagnostic Microbiology and Infectious Diseases
    • Editorial board, Manual of Clinical Microbiology
  • Videos & Media +
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