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Photo of Dr. Charles Eberhart

Charles George Eberhart, MD PhD

Director, Ophthalmic Pathology
Professor of Pathology
Male
Appointment Phone

410-955-5568

Main Location

The Johns Hopkins Hospital

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Titles

  • Director, Ophthalmic Pathology
  • Professor of Pathology
  • Professor of Oncology
  • Associate Professor of Ophthalmology

Centers & Institutes

  • Sidney Kimmel Comprehensive Cancer Center

Expertise

Pathology

Biography

Dr. Charles Eberhart is a professor of pathology and oncology and an associate professor of ophthalmology at the Johns Hopkins University School of Medicine. His research focuses on molecular genetics of medulloblastoma, glioblastoma, uveal melanoma and other tumors of the brain and eye. Dr. Eberhart serves as the director of Ophthalmic Pathology within the Wilmer Eye Institute.

Dr. Eberhart’s lab focus is on the Notch and Hedgehog pathways, which play a key role in both normal brain and eye development and in neoplasia. He is currently analyzing the effects of Notch and Hedgehog pathway blockade on cancer stem cells in brain and eye tumors.

He received his undergraduate degree in biochemistry from the University of Texas at Austin and earned his M.D./Ph.D. from UT Southwestern Medical School. He completed both a residency in anatomic pathology and a fellowship in neuropathology at The Johns Hopkins Hospital. Dr. Eberhart joined the Johns Hopkins faculty in 2001.

Dr. Eberhart has been recognized with the Howard Hughes Medical Institute Postdoctoral Research Fellowship for Physicians, and career awards from the Burroughs Wellcome Fund and the National Institutes of Health. He has published more than 80 research articles and is on the editorial board of the Journal of Neuro-Oncology, Brain Pathology and the Journal of Neuropathology and Experimental Neurology.

Languages

  • English
  • German

Memberships

American Association for Cancer Research

American Association of Neuropathology

American Society for Investigative Pathology

Society for Neuro-Oncology

Eastern Cooperative Oncology Group

New Approaches to Brain Tumor Therapy (NABTT) Consortium New York Academy of Sciences

Verhoeff Zimmerman Society

Association for Research in Vision and Ophthalmology

Additional Resources +
  • Education +

    Training

    • University of Texas Southwestern Medical School (Dallas TX) (1997)

    Residencies

    • Johns Hopkins University School of Medicine / Pathology (Baltimore MD) (2001)

    Certifications

    • American Board of Pathology / Anatomic Pathology (2003)
    • American Board of Pathology / Neuropathology (2003)
  • Research & Publications +

    Research Summary

    Dr. Eberhart and his lab members study the molecular genetics of medulloblastoma, glioblastoma, uveal melanoma and other tumors of the brain and eye. They focus on the Notch and Hedgehog pathways, which play a key role in both normal brain and eye development and in neoplasia. They are currently analyzing the effects of Notch and Hedgehog pathway blockade on cancer stem cells in brain and eye tumors and are also investigating the basis of the sometimes antagonistic effects of various Notch receptors in medulloblastoma and how this relates to their roles in neural stem-cell proliferation and differentiation. They are also examining the role of c-Myc in the stem cell phenotype of cancer.

    Selected Publications

    1. Chu, L.C.; Eberhart, C.G.; Grossman, S.A.; Herman, J.G. Epigenetic silencing of multiple genes in primary CNS lymphoma. Int J Cancer. 2006 Nov 15;119(10):2487-2491.
    2. Dang, L.; Fan, X.; Chaudhry, A.; Wang, M.; Gaiano, N.; Eberhart, C.G. Notch3 signaling initiates choroid plexus tumor formation. Oncogene. 2006 Jan 19;25(3):487-491.
    3. Dixit, V.D.; Weeraratna, A.T.; Yang, H.; Bertak, D.; Cooper-Jenkins, A.; Riggins, G.J.; Eberhart, C.G.; Taub, D.D. Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility. The Journal of biological chemistry. 2006 Jun 16;281(24):16681-16690.
    4. Eberhart, C.G.; Copeland, J.; Abel, T.W. Brief Report: S6 Ribosomal Protein Phosphorylation in Autistic Frontal Cortex and Cerebellum: a Tissue Array Analysis. J Autism Dev Disord. 2006 Jul 15;36(1131-1135).
    5. Fan, X.; Matsui, W.; Khaki, L.; Stearns, D.; Chun, J.; Li, Y.M.; Eberhart, C.G. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 2006 Aug 1;66(15):7445-7452.
    6. Gallia, G.L.; Rand, V.; Siu, I.M.; Eberhart, C.G.; James, C.D.; Marie, S.K.; Oba-Shinjo, S.M.; Carlotti, C.G.; Caballero, O.L.; Simpson, A.J.; Brock, M.V.; Massion, P.P.; Carson, B.S., Sr.; Riggins, G.J. PIK3CA gene mutations in pediatric and adult glioblastoma multiforme. Mol Cancer Res. 2006 Oct;4(10):709-714.
    7. Park, J.T.; Li, M.; Nakayama, K.; Mao, T.L.; Davidson, B.; Zhang, Z.; Kurman, R.J.; Eberhart, C.G.; Shih Ie, M.; Wang, T.L. Notch3 gene amplification in ovarian cancer. Cancer Res. 2006 Jun 15;66(12):6312-6318.
    8. Stearns, D.; Chaudhry, A.; Abel, T.W.; Burger, P.C.; Dang, C.V.; Eberhart, C.G. c-myc overexpression causes anaplasia in medulloblastoma. Cancer Res. 2006 Jan 15;66(2):673-681.
    9. Bar, E.E.; Chaudhry, A.; Farah, M.H.; Eberhart, C.G. Hedgehog signaling promotes medulloblastoma survival via Bc/II. Am J Pathol. 2007 Jan;170(1):347-355.
    10. Bar, E.E.; Chaudhry, A.; Lin, A.; Fan, X.; Schreck, K.; Matsui, W.; Piccirillo, S.; Vescovi, A.L.; DiMeco, F.; Olivi, A.; Eberhart, C.G. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells. 2007 Oct;25(10):2524-2533.
    11. Eberhart, C.G. In search of the medulloblast: neural stem cells and embryonal brain tumors. Neurosurg Clin N Am. 2007 Jan;18(1):59-69, viii-ix.
    12. Li, T.; Wen, H.; Brayton, C.; Das, P.; Smithson, L.A.; Fauq, A.; Fan, X.; Crain, B.J.; Price, D.L.; Golde, T.E.; Eberhart, C.G.; Wong, P.C. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase. J Biol Chem. 2007 Nov 2;282(44):32264-32273.
    13. Pardo, C.A.; Eberhart, C.G. The neurobiology of autism. Brain Pathol. 2007 Oct;17(4):434-447.
    14. Rodriguez, F.J.; Eberhart, C.; O'Neill, B.P.; Slezak, J.; Burger, P.C.; Goldthwaite, P.; Wu, W.; Giannini, C. Histopathologic grading of adult medulloblastomas. Cancer. 2007 Jun 15;109(12):2557-2565.
    15. Bar, E.E.; Lin, A.; Tihan, T.; Burger, P.C.; Eberhart, C.G. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol. 2008 Sep;67(9):878-887.
    16. Briggs, K.J.; Corcoran-Schwartz, I.M.; Zhang, W.; Harcke, T.; Devereux, W.L.; Baylin, S.B.; Eberhart, C.G.; Watkins, D.N. Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. Genes Dev. 2008 Mar 15;22(6):770-785.
    17. Briggs, K.J.; Eberhart, C.G.; Watkins, D.N. Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction. Cancer Res. 2008 Nov 1;68(21):8654-8656.
    18. Chen, C.S.; Miller, N.R.; Lane, A.; Eberhart, C. Third cranial nerve palsy caused by intracranial extension of a sino-orbital natural killer T-cell lymphoma. J Neuroophthalmol. 2008 Mar;28(1):31-35.
    19. Eberhart, C.G. Even cancers want commitment: lineage identity and medulloblastoma formation. Cancer Cell. 2008 Aug 12;14(2):105-107.
    20. Fan, X.; Eberhart, C.G. Medulloblastoma stem cells. J Clin Oncol. 2008 Jun 10;26(17):2821-2827.
    21. Gessi, M.; Giangaspero, F.; Lauriola, L.; Gardiman, M.; Scheithauer, B.W.; Halliday, W.; Hawkins, C.; Rosenblum, M.K.; Burger, P.C.; Eberhart, C.G. Embryonal Tumors With Abundant Neuropil and True Rosettes: A Distinctive CNS Primitive Neuroectodermal Tumor. Am J Surg Pathol. 2008 Nov 3.
    22. Li , Y.; Guessous, F.; Johnson, E.B.; Eberhart, C.G.; Li, X.N.; Shu, Q.; Fan, S.; Laterra, J.; Schiff, D.; Abounader, R. Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large cell medulloblastoma. Laboratory Investigation. 2008 Feb;88:98-111.
    23. Macgregor, A.M.; Eberhart, C.G.; Fraig, M.; Lu, J.; Halushka, M.K. Tissue Inhibitor of Matrix Metalloproteinase-3 Levels in the Extracellular Matrix of Lung, Kidney, and Eye Increase With Age. J Histochem Cytochem. 2008 Oct 27.
    24. Siu, I.M.; Bai, R.; Gallia, G.L.; Edwards, J.B.; Tyler, B.M.; Eberhart, C.G.; Riggins, G.J. Coexpression of neuronatin splice forms promotes medulloblastoma growth. Neuro Oncol. 2008 Oct;10(5):716-724.
    25. Yi, J.M.; Tsai, H.C.; Glockner, S.C.; Lin, S.; Ohm, J.E.; Easwaran, H.; James, C.D.; Costello, J.F.; Riggins, G.; Eberhart, C.G.; Laterra, J.; Vescovi, A.L.; Ahuja, N.; Herman, J.G.; Schuebel, K.E.; Baylin, S.B. Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res. 2008 Oct 1;68(19):8094-8103.
    26. Ayres, B.; Miller, N.R.; Eberhart, C.G.; Dibernardo, C.W. Ultrasound features of orbital granular cell tumor. Ophthal Plast Reconstr Surg. 2009 Jul-Aug;25(4):320-322.
    27. Barnes, M.; Eberhart, C.G.; Collins, R.; Tihan, T. Expression of p75NTR in fetal brain and medulloblastomas: evidence of a precursor cell marker and its persistence in neoplasia. J Neurooncol. 2009 Apr;92(2):193-201.
    28. Gessi, M.; Giangaspero, F.; Lauriola, L.; Gardiman, M.; Scheithauer, B.W.; Halliday, W.; Hawkins, C.; Rosenblum, M.K.; Burger, P.C.; Eberhart, C.G. Embryonal tumors with abundant neuropil and true rosettes: a distinctive CNS primitive neuroectodermal tumor. Am J Surg Pathol. 2009 Feb;33(2):211-217.
    29. Macgregor, A.M.; Eberhart, C.G.; Fraig, M.; Lu, J.; Halushka, M.K. Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age. J Histochem Cytochem. 2009 Mar;57(3):207-213.
    30. Mullendore, M.E.; Koorstra, J.B.; Li, Y.M.; Offerhaus, G.J.; Fan, X.; Henderson, C.M.; Matsui, W.; Eberhart, C.G.; Maitra, A.; Feldmann, G. Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clin Cancer Res. 2009 Apr 1;15(7):2291-2301.
    31. Nasonkin, I.; Mahairaki, V.; Xu, L.; Hatfield, G.; Cummings, B.J.; Eberhart, C.; Ryugo, D.K.; Maric, D.; Bar, E.; Koliatsos, V.E. Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells. 2009 Oct;27(10):2414-2426.
    32. Northcott, P.A.; Nakahara, Y.; Wu, X.; Feuk, L.; Ellison, D.W.; Croul, S.; Mack, S.; Kongkham, P.N.; Peacock, J.; Dubuc, A.; Ra, Y.S.; Zilberberg, K.; McLeod, J.; Scherer, S.W.; Sunil Rao, J.; Eberhart, C.G.; Grajkowska, W.; Gillespie, Y.; Lach, B.; Grundy, R.; Pollack, I.F.; Hamilton, R.L.; Van Meter, T.; Carlotti, C.G.; Boop, F.; Bigner, D.; Gilbertson, R.J.; Rutka, J.T.; Taylor, M.D. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet. 2009 Apr;41(4):465-472.
    33. Oster, S.F.; Ebrahimi, K.B.; Eberhart, C.G.; Schein, O.D.; Stark, W.J.; Jun, A.S. A clinicopathologic series of primary graft failure after Descemet's stripping and automated endothelial keratoplasty. Ophthalmology. 2009 Apr;116(4):609-614.
    34. Roda, R.H.; Gallia, G.L.; Eberhart, C.G.; Weingart, J.D.; Laterra, J. Epilepsy and temporal lobe injury after skull base proton beam therapy. J Clin Neurosci. 2009 Sep;16(9):1220-1221.
    35. Sabet-Peyman, E.J.; Eberhart, C.G.; Janjua, K.; Shah, S.M.; Do, D.V.; Nguyen, Q.D. Persistent intermediate uveitis associated with latent manifestation of facial large B-cell non-Hodgkin lymphoma. Ocul Immunol Inflamm. 2009 Sep-Oct;17(5):322-324.
    36. Sun, P.; Xia, S.; Lal, B.; Eberhart, C.G.; Quinones-Hinojosa, A.; Maciaczyk, J.; Matsui, W.; Dimeco, F.; Piccirillo, S.M.; Vescovi, A.L.; Laterra, J. DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation. Stem Cells. 2009 Jul;27(7):1473-1486.
    37. von Bueren, A.O.; Shalaby, T.; Oehler-Janne, C.; Arnold, L.; Stearns, D.; Eberhart, C.G.; Arcaro, A.; Pruschy, M.; Grotzer, M.A. RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells. BMC Cancer. 2009 Jan 10;9(1):10.
    38. Bar, E.E.; Lin, A.; Mahairaki, V.; Matsui, W.; Eberhart, C.G. Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol. 2010 Sep;177(3):1491-1502.
    39. Cho, Y.J.; Tsherniak, A.; Tamayo, P.; Santagata, S.; Ligon, A.; Greulich, H.; Berhoukim, R.; Amani, V.; Goumnerova, L.; Eberhart, C.G.; Lau, C.C.; Olson, J.M.; Gilbertson, R.J.; Gajjar, A.; Delattre, O.; Kool, M.; Ligon, K.; Meyerson, M.; Mesirov, J.P.; Pomeroy, S.L. Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome. J Clin Oncol. 2010 Dec 6.
    40. Engler, C.; Kelliher, C.; Spitze, A.R.; Speck, C.L.; Eberhart, C.G.; Jun, A.S. Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway? Am J Ophthalmol. 2010 Feb;149(2):194-202 e192.
    41. Fan, X.; Khaki, L.; Zhu, T.S.; Soules, M.E.; Talsma, C.E.; Gul, N.; Koh, C.; Zhang, J.; Li, Y.M.; Maciaczyk, J.; Nikkhah, G.; Dimeco, F.; Piccirillo, S.; Vescovi, A.L.; Eberhart, C.G. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells. 2010 Jan;28(1):5-16.
    42. Gurel, B.; Ali, T.Z.; Montgomery, E.A.; Begum, S.; Hicks, J.; Goggins, M.; Eberhart, C.G.; Clark, D.P.; Bieberich, C.J.; Epstein, J.I.; De Marzo, A.M. NKX3.1 as a marker of prostatic origin in metastatic tumors. Am J Surg Pathol. 2010 Aug;34(8):1097-1105 
    43. Jain, D.; Ebrahimi, K.B.; Miller, N.R.; Eberhart, C.G. Intraorbital meningiomas: a pathologic review using current World Health Organization criteria. Arch Pathol Lab Med. 2010 May;134(5):766-770 
    44. Jain, D.; Singh, K.; Chirumamilla, S.; Bibat, G.M.; Blue, M.E.; Naidu, S.R.; Eberhart, C.G. Ocular MECP2 protein expression in patients with and without Rett syndrome. Pediatr Neurol. 2010 Jul;43(1):35-40.
    45. Johnson, M.W.; Eberhart, C.G.; Perry, A.; Tihan, T.; Cohen, K.J.; Rosenblum, M.K.; Rais-Bahrami, S.; Goldthwaite, P.; Burger, P.C. Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors. The American Journal of Surgical Pathology. 2010;34(12):1783-1791.
    46. Lee, B.S.; Frankfort, B.J.; Eberhart, C.G.; Weinberg, R.S. Diagnosis of Intravascular Lymphoma by a Novel Biopsy Site. Ophthalmology. 2010 Oct 28.
    47. Nakahara, Y.; Northcott, P.A.; Li, M.; Kongkham, P.N.; Smith, C.; Yan, H.; Croul, S.; Ra, Y.S.; Eberhart, C.; Huang, A.; Bigner, D.; Grajkowska, W.; Van Meter, T.; Rutka, J.T.; Taylor, M.D. Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia. 2010 Jan;12(1):20-27 Not supported through NIH funding.
    48. Northcott, P.A.; Korshunov, A.; Witt, H.; Hielscher, T.; Eberhart, C.G.; Mack, S.; Bouffet, E.; Clifford, S.C.; Hawkins, C.E.; French, P.; Rutka, J.T.; Pfister, S.; Taylor, M.D. Medulloblastoma Comprises Four Distinct Molecular Variants. J Clin Oncol. 2010 Dec 6.
    49. Pfister, S.M.; Korshunov, A.; Kool, M.; Hasselblatt, M.; Eberhart, C.; Taylor, M.D. Molecular diagnostics of CNS embryonal tumors. Acta Neuropathol. 2010 Nov;120(5):553-566.
    50. Raabe, E.H.; Eberhart, C.G. High-risk medulloblastoma: does c-myc amplification overrule histopathology? Pediatr Blood Cancer. 2010 Mar;54(3):344-345 
    51. Schreck, K.C.; Taylor, P.; Marchionni, L.; Gopalakrishnan, V.; Bar, E.E.; Gaiano, N.; Eberhart, C.G. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clin Cancer Res. 2010 Dec 15;16(24):6060-6070 
    52. Shahi, M.H.; Afzal, M.; Sinha, S.; Eberhart, C.G.; Rey, J.A.; Fan, X.; Castresana, J.S. Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples. J Neurooncol. 2010 Sep 19.
    53. Shahi, M.H.; Afzal, M.; Sinha, S.; Eberhart, C.G.; Rey, J.A.; Fan, X.; Castresana, J.S. Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma. BMC Cancer. 2010;10:614.
    54. Singh, K.; Rajan, K.D.; Eberhart, C. Orbital necrobiotic xanthogranuloma associated with systemic IgG4 disease. Ocul Immunol Inflamm. 2010 Oct;18(5):373-378 
    55. Siu, I.M.; Tyler, B.M.; Chen, J.X.; Eberhart, C.G.; Thomale, U.W.; Olivi, A.; Jallo, G.I.; Riggins, G.J.; Gallia, G.L. Establishment of a human glioblastoma stemlike brainstem rodent tumor model. Journal of neurosurgeryPediatrics. 2010;6(1):92-97.
    56. Ying, M.; Sang, Y.; Li, Y.; Guerrero-Cazares, H.; Quinones-Hinojosa, A.; Vescovi, A.L.; Eberhart, C.G.; Xia, S.; Laterra, J. KLF9, A Differentiation-Associated Transcription Factor, Suppresses Notch1 Signaling and Inhibits Glioblastoma-Initiating Stem Cells. Stem cells. 2010;Epub 11/18/10(Journal Article).
    57. Yustein, J.T.; Liu, Y.C.; Gao, P.; Jie, C.; Le, A.; Vuica-Ross, M.; Chng, W.J.; Eberhart, C.G.; Bergsagel, P.L.; Dang, C.V. Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3534-3539.
    58. Eberhart, C.G. Molecular diagnostics in embryonal brain tumors. Brain Pathol. 2011 Jan;21(1):96-104.
    59. Lim, K.J.; Bisht, S.; Bar, E.E.; Maitra, A.; Eberhart, C.G. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ther. 2011 Mar 1;11(5).

    Lab

    The Eberhart, Rodriguez and Raabe laboratories are focused on understanding how tumors of the brain and eye form and grow. Their studies frequently use normal development to guide this investigation of the neoplastic process, as rapid growth and cellular migration are common to both processes. They have implicated Hedgehog, Notch and other developmentally significant signaling cascades in the initiation and ongoing growth of malignant brain tumors such as medulloblastoma and glioblastoma. They are also engaged in preclinical testing of pharmacological agents that target these pathways in brain and eye tumors. Another related area of interest in the lab is the relationship between stem cells and cancer. The possibility that transformed stem cells represent the origins of brain and eye tumors, as well as the hypothesis that “cancer stem cells” are required for long-term tumor self renewal and growth, are both active areas of investigation. Finally, they have recently shown that alterations activating BRAF are common in pediatric low grade gliomas, and are examining the pathobiology of this complex group of tumors.

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Lucien J. Rubenstain Award for Best Paper in Neuro-oncology, AANP Meeting, 2005

    Jean D Wilson Distinguished Alumni Lecturer, UT Southwestern MSTP, 2004

    Burroughs Wellcome Fund Career Award 2001 - 2005

    Howard Hughes Postdoctoral Research Fellowship for Physicians 2000 - 2003

    Merck MSTP Fellow, 1996 - 1997

    March of Dimes Graduate Fellow, 1992 - 1994

    Deutches Akademisches Austauschdienst Graduate Fellow, 1988 - 1989

    UT Southwestern Medical School: Honors in Pathology, Urology, Medicine

    University of Texas at Austin: National Merit Scholar, Phi Beta Kappa

    Professional Activities

    Autism Tissue Program Scientific Board Member, 2007 – present

    Society for Neurooncology (SNO) Annual Meeting Abstract Review for Scientific Program, 2006, 2007

    WHO Classification of Tumours of the Nervous System Editorial and Consensus Conference, Heidelberg Invited Participant and Group D Rapporteur, 2006

    Organizer and Chair, Medulloblastoma minisymposium XVIth International Congress of Neuropathology, 2006

    Editorial board, Journal of Neuropathology and Experimental Neurology, 2005 - present

    Editorial board, Neuro-Oncology, 2006 - present

    Scientific Review Council Member, Cure Autism Now (CAN), 2004 - 2007

    Principal investigator (Johns Hopkins), NABTT Study “A Prospective National Study to Molecularly and Genetically Characterize Human Gliomas,” 2003 – 2007

    Pathology reviewer, ECOG Study E1F02: (Systemic High-Dose Methotrexate Followed by Radiation for the Treatment of GBM), 2003 - 2007

    Co-chair, Pathology and Tissue Committee, New Approaches to Brain Tumor Therapy (NABTT) Consortium, 2003 - 2006

  • Videos & Media +

    Videos

    Charles Eberhart discusses brain cancer stem cells

    Johns Hopkins scientist Charles Eberhart discusses recent research on blocking pathways that contribute to brain cancer stem cell growth.

  • Events +
  • Contact & Locations +

    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410-955-5568
    Location Map

    Department/Division

    • Pathology

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