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Photo of Dr. Carmelo Cuffari

Carmelo Cuffari, M.D.

Associate Professor of Pediatrics

Male  | Languages: English, French, Italian

Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Associate Professor of Pediatrics

Centers & Institutes



The Johns Hopkins Hospital

Appointment Phone: 410-955-8769

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-8765
Fax: 410-955-1464

Johns Hopkins Community Physicians - Frederick

Appointment Phone: 410-955-8769

45 Thomas Johnson Drive
Suite 109
Frederick, MD 21702 map
Phone: 301-696-1000


Pediatric Gastroenterology

Research Interests

Immunomodulatory mechanism of action of anti-metabolite drugs in patients with inflammatory bowel disease; Pharmacogenomics of immunosuppressant drugs in patients with inflammatory bowel disease and in children post-liver transplantation


Dr. Carmen Cuffari is an associate professor of pediatrics at the Johns Hopkins University School of Medicine. His area of clinical expertise is pediatric gastroenterology, with a particular focus on inflammatory bowel disease (IBD).

Dr. Cuffari received his medical degree at the University of Ottawa. He went on to complete a residency in pediatrics at The Children’s Hospital of Eastern Ontario in Ottawa, Canada, and a fellowship in pediatric gastroenterology at St. Justine’s Hospital in Montreal, Canada.

His research focuses on the pharmacogenomics of immunosuppressant drugs in patients with inflammatory bowel disease and in children post-liver transplantation, as well as the immunomodulatory mechanism of action of anti-metabolite drugs in patients with inflammatory bowel disease.

Dr. Cuffari has over 50 publications in peer-reviewed journals. He served as associate editor of the journal Inflammatory Bowl Diseases and reviews manuscripts for several other journals, including Clinical Gastroenterology and Hepatology, Journal of Clinical Gastroenterology, American Journal of Gastroenterology and The Pediatric Journal of Gastroenterology and Nutrition. He is certified by the American Board of Pediatrics. more

    Additional Information

  • Education +


    • Faculty Of Health Sciences University Of Ottawa / MD (1989)


    • Children's Hospital of Eastern Ontario / Pediatrics (1993)


    • St Justine's Hospital / Pediatric Gastroenterology (1996)


    • American Board of Pediatrics / Pediatric Gastroenterology (1997, 2012)
  • Research & Publications +

    Selected Publications View all on PubMed

    Vasilescu A, Cuffari C, Santo Domingo L, Scheimann AO. "Predictors of Severity in Childhood Pancreatitis: Correlation With Nutritional Status and Racial Demographics." Pancreas. 2014 Dec 2. [Epub ahead of print] PubMed PMID: 25469545.

    Walia R, Garg S, Song Y, Girotra M, Cuffari C, Fricke WF, Dutta SK. "Efficacy of fecal microbiota transplantation in 2 children with recurrent Clostridium difficile infection and its impact on their growth and gut microbiome." J Pediatr Gastroenterol Nutr. 2014 Nov;59(5):565-70. doi: 10.1097/MPG.0000000000000495. PubMed PMID: 25023578.

    Wang MH, Okazaki T, Kugathasan S, Cho JH, Isaacs KL, Lewis JD, Smoot DT, Valentine JF, Kader HA, Ford JG, Harris ML, Oliva-Hemker M, Cuffari C, Torbenson MS, Duerr RH, Silverberg MS, Rioux JD, Taylor KD, Nguyen GC, Wu Y, Datta LW, Hooker S, Dassopoulos T, Kittles RA, Kao LW, Brant SR. "Contribution of higher risk genes and European admixture to Crohn's disease in African Americans." Inflamm Bowel Dis. 2012 Dec;18(12):2277-87. doi: 10.1002/ibd.22931. Epub 2012 Mar12. PubMed PMID: 22411504; PubMed Central PMCID: PMC3810419.

    Conklin LS, Cuffari C, Okazaki T, Miao Y, Saatian B, Chen TE, Tse M, Brant SR, Li X. "6-Mercaptopurine transport in human lymphocytes: correlation with drug-induced cytotoxicity." J Dig Dis. 2012 Feb;13(2):82-93. doi: 10.1111/j.1751-2980.2011.00556.x. PubMed PMID: 22257476; PubMed Central PMCID:PMC3758926.

    Chirumamilla SR, He C, Racusen LC, Scheimann AO, Cuffari C. "Acute kidney injury in a girl with ulcerative colitis and cytomegalovirus-induced focal segmental glomerular sclerosis." World J Pediatr. 2013 Feb;9(1):84-6. doi:10.1007/s12519-011-0302-8. Epub 2011 Aug 27. PubMed PMID: 21874614.

  • Academic Affiliations & Courses +
  • Activities & Honors +


    • Associate Editor
       Inflammatory Bowel Diseases
    • Manuscript Reviewer
       American Journal of Gastroenterology
    • Manuscript Reviewer
       Clinical Gastroenterology and Hepatology
    • Manuscript Reviewer
       Journal of Clinical Gastroenterology
    • Manuscript Reviewer
       The Pediatric Journal of Gastroenterology and Nutrition

    Professional Activities

    • Associate Editor, Inflammatory Bowel Diseases
    • Manuscript Reviewer, Clinical Gastroenterology and Hepatology
    • Manuscript Reviewer, Journal of Clinical Gastroenterology
    • Manuscript Reviewer, American Journal of Gastroenterology
    • Manuscript Reviewer, The Pediatric Journal of Gastroenterology and Nutrition
  • Videos & Media +
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