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Photo of Dr. Joel Nee-Lartey Blankson, M.D., Ph.D.

Joel Nee-Lartey Blankson, M.D., Ph.D.

Associate Professor of Medicine


Appointment Phone


Main Location

Johns Hopkins Medicine - Green Spring Station

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Associate Professor of Medicine
  • Associate Professor of Molecular and Comparative Pathobiology



Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-1725

10755 Falls Road
Pavilion I
Lutherville, MD 21093 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-1725

601 N. Caroline Street
Baltimore, MD 21287 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-1725

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

The Johns Hopkins Hospital

600 N. Wolfe Street
Carnegie 446D1
Baltimore, MD 21287 map

Contact for Research Inquiries

833 Miller Research Building
, map


HIV Pathogenesis, Infectious Disease

Research Interests

Natural Control of HIV-1 Infection

    Additional Information

  • Education +


    • Cornell University Medical College / MD; Medicine (1995)


    • Johns Hopkins University School of Medicine / Infectious Diseases (1998)


    • Johns Hopkins University School of Medicine / Infectious Diseases (2002)


    • American Board of Internal Medicine / Infectious Disease (2002, 2012)
  • Research & Publications +

    Selected Publications

    1: Salgado M, Swanson MD, Pohlmeyer CW, Buckheit RW 3rd, Wu J, Archin NM,Williams TM, Margolis DM, Siliciano RF, Garcia JV, Blankson JN. HLA-B*57 EliteSuppressor and Chronic Progressor HIV-1 Isolates Replicate Vigorously and CauseCD4+ T cell Depletion in Humanized BLT Mice. J Virol. 2014 Jan 3. [Epub ahead of print] PubMed PMID: 24390323.2: Pohlmeyer CW, Buckheit RW 3rd, Siliciano RF, Blankson JN. CD8+ T cells fromHLA-B*57 elite suppressors effectively suppress replication of HIV-1 escapemutants. Retrovirology. 2013 Dec 12;10:152. doi: 10.1186/1742-4690-10-152. PubMedPMID: 24330837; PubMed Central PMCID: PMC3878989.3: Chiu YL, Shan L, Huang H, Haupt C, Bessell C, Canaday DH, Zhang H, Ho YC,Powell JD, Oelke M, Margolick JB, Blankson JN, Griffin DE, Schneck JP. Sprouty-2 regulates HIV-specific T cell polyfunctionality. J Clin Invest. 2013 Dec 2. pii: 70510. doi: 10.1172/JCI70510. [Epub ahead of print] PubMed PMID: 24292711; PubMedCentral PMCID: PMC3871241.4: Ho YC, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DI, Lai J, BlanksonJN, Siliciano JD, Siliciano RF. Replication-competent noninduced proviruses inthe latent reservoir increase barrier to HIV-1 cure. Cell. 2013 Oct24;155(3):540-51. doi: 10.1016/j.cell.2013.09.020. Epub 2013 Oct 24. PubMed PMID:24243014; PubMed Central PMCID: PMC3896327.5: Salgado M, Gandhi S, Buckheit RW, Berkenblit GV, Blankson JN. Evolution of an Attenuated HIV-1 Isolate in an Elite Suppressor. AIDS Res Hum Retroviruses. 2013 Nov 13. [Epub ahead of print] PubMed PMID: 24117037.6: Buckheit RW 3rd, Siliciano RF, Blankson JN. Primary CD8+ T cells from elitesuppressors effectively eliminate non-productively HIV-1 infected resting andactivated CD4+ T cells. Retrovirology. 2013 Jul 1;10:68. doi:10.1186/1742-4690-10-68. PubMed PMID: 23816179; PubMed Central PMCID: PMC3702406.7: Laird GM, Eisele EE, Rabi SA, Lai J, Chioma S, Blankson JN, Siliciano JD,Siliciano RF. Rapid quantification of the latent reservoir for HIV-1 using aviral outgrowth assay. PLoS Pathog. 2013;9(5):e1003398. doi:10.1371/journal.ppat.1003398. Epub 2013 May 30. PubMed PMID: 23737751; PubMedCentral PMCID: PMC3667757.8: Wendel SK, Mullis CE, Eshleman SH, Blankson JN, Moore RD, Keruly JC,Brookmeyer R, Quinn TC, Laeyendecker O. Effect of natural and ARV-induced viralsuppression and viral breakthrough on anti-HIV antibody proportion and avidity inpatients with HIV-1 subtype B infection. PLoS One. 2013;8(2):e55525. doi:10.1371/journal.pone.0055525. Epub 2013 Feb 20. PubMed PMID: 23437058; PubMedCentral PMCID: PMC3577851.9: Buckheit RW 3rd, Salgado M, Silciano RF, Blankson JN. Inhibitory potential of subpopulations of CD8+ T cells in HIV-1-infected elite suppressors. J Virol. 2012Dec;86(24):13679-88. doi: 10.1128/JVI.02439-12. Epub 2012 Oct 10. PubMed PMID:23055552; PubMed Central PMCID: PMC3503034.10: Durand CM, Blankson JN, Siliciano RF. Developing strategies for HIV-1eradication. Trends Immunol. 2012 Nov;33(11):554-62. doi:10.1016/ Epub 2012 Aug 3. Review. PubMed PMID: 22867874.11: Buckheit RW 3rd, Salgado M, Martins KO, Blankson JN. The implications ofviral reservoirs on the elite control of HIV-1 infection. Cell Mol Life Sci. 2013Mar;70(6):1009-19. doi: 10.1007/s00018-012-1101-7. Epub 2012 Aug 4. Review.PubMed PMID: 22864624.12: Thayil SM, Ho YC, Bollinger RC, Blankson JN, Siliciano RF, Karakousis PC,Page KR. Mycobacterium tuberculosis complex enhances susceptibility of CD4 Tcells to HIV through a TLR2-mediated pathway. PLoS One. 2012;7(7):e41093. doi:10.1371/journal.pone.0041093. Epub 2012 Jul 23. PubMed PMID: 22844428; PubMedCentral PMCID: PMC3402510.13: Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, Zhang H, MargolickJB, Blankson JN, Siliciano RF. Stimulation of HIV-1-specific cytolytic Tlymphocytes facilitates elimination of latent viral reservoir after virusreactivation. Immunity. 2012 Mar 23;36(3):491-501. doi:10.1016/j.immuni.2012.01.014. Epub 2012 Mar 8. PubMed PMID: 22406268; PubMedCentral PMCID: PMC3501645.14: Buckheit RW 3rd, Allen TG, Alme A, Salgado M, O'Connell KA, Huculak S,Falade-Nwulia O, Williams TM, Gallant JE, Siliciano RF, Blankson JN. Host factorsdictate control of viral replication in two HIV-1 controller/chronic progressortransmission pairs. Nat Commun. 2012 Mar 6;3:716. doi: 10.1038/ncomms1697. PubMedPMID: 22395607; PubMed Central PMCID: PMC3549550.15: Durand C, Ambinder R, Blankson J, Forman S. HIV-1 and hematopoietic stem celltransplantation. Biol Blood Marrow Transplant. 2012 Jan;18(1 Suppl):S172-6. doi: 10.1016/j.bbmt.2011.10.027. Review. PubMed PMID: 22226103; PubMed Central PMCID: PMC3615639.16: Witwer KW, Watson AK, Blankson JN, Clements JE. Relationships of PBMCmicroRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infectedelite suppressors and viremic patients. Retrovirology. 2012 Jan 12;9:5. doi:10.1186/1742-4690-9-5. PubMed PMID: 22240256; PubMed Central PMCID: PMC3292811.17: Salgado M, Rabi SA, O'Connell KA, Buckheit RW 3rd, Bailey JR, Chaudhry AA,Breaud AR, Marzinke MA, Clarke W, Margolick JB, Siliciano RF, Blankson JN.Prolonged control of replication-competent dual- tropic human immunodeficiencyvirus-1 following cessation of highly active antiretroviral therapy.Retrovirology. 2011 Dec 5;8:97. doi: 10.1186/1742-4690-8-97. PubMed PMID:22141397; PubMed Central PMCID: PMC3293762.18: O'Connell KA, Rabi SA, Siliciano RF, Blankson JN. CD4+ T cells from elitesuppressors are more susceptible to HIV-1 but produce fewer virions than cellsfrom chronic progressors. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E689-98. doi: 10.1073/pnas.1108866108. Epub 2011 Aug 22. PubMed PMID: 21873218; PubMedCentral PMCID: PMC3174588.19: Blankson JN. Killing the messenger to maintain control of HIV. Nat Med. 2011 Aug 4;17(8):927-8. doi: 10.1038/nm.2427. PubMed PMID: 21818087.20: O'Connell KA, Hegarty RW, Siliciano RF, Blankson JN. Viral suppression ofmultiple escape mutants by de novo CD8(+) T cell responses in a humanimmunodeficiency virus-1 infected elite suppressor. Retrovirology. 2011 Aug3;8:63. doi: 10.1186/1742-4690-8-63. PubMed PMID: 21812985; PubMed Central PMCID:PMC3173334.
  • Academic Affiliations & Courses +

    Graduate Program Affiliation


    Cellular and Molecular Medicine

  • Activities & Honors +
  • Videos & Media +
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