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Timothy Michael Pawlik, M.D., M.P.H., Ph.D.
Chief, Division of Surgical Oncology
Professor of Surgery
Expertise: Alimentary Tract Diseases, Benign Liver Lesions, Bile Duct Cancer, Bile Duct Disease, Carcinoid Syndrome, Carcinoid Tumors, Cholangiocarcinoma, Colorectal Metastases to the Liver, Gallbladder Cancer, General Surgery, Hemangiomas, Hepatobiliary Conditions, Hepatobiliary Malignancies, Hepatocellular Cancer, Intrahepatic Cholangiocarcinoma, Klatskin Tumors, Liver Cancer, Liver Cysts, Liver Disease, Liver Tumors, Neuroendocrine Tumors, Pancreatic and Biliary Disease, Pancreatic Cancer, Pancreatic Tumors, Surgical Oncology, Whipple Procedure ...read more
Research Interests: Experimental therapeutics of hepatic malignancies; Clinical trials in gastrointestinal malignancies; Clinical ethics
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Dr. Pawlik received his undergraduate degree from Georgetown University and his medical degree from Tufts University School of Medicine. Dr. Pawlik completed surgical training at the University of Michigan Hospital and spent two years at the Massachusetts General Hospital as a surgical oncology research fellow. He then went on for advanced training in surgical oncology at The University of Texas M. D. Anderson Cancer Center in Houston. Dr. Pawliks main clinical interests include alimentary tract surgery, with a special interest in hepatic and pancreatobiliary diseases. Dr. Pawlik also has an interest in medical ethics and completed a fellowship in medical ethics at the Harvard School of Public Health as well as a Masters in Theology from Harvard Divinity School in Boston. In addition, Dr. Pawlik has received a PhD from the Johns Hopkins Bloomberg School of Public Health in Clinical Investigations.
Dr. Pawlik took his first faculty appointment at Johns Hopkins in 2005, where he is currently Professor of Surgery and Oncology, as well as the Director of the Johns Hopkins Liver Tumor Center. Dr. Pawlik holds the John L. Cameron Chair of Alimentary Tract Diseases and is Chief of the Division of Surgical Oncology. Dr. Pawlik has given our 200 invited talks both nationally and internationally in 20 different countries. Dr. Pawlik has published over 250 articles and 30 book chapters. Dr. Pawlik has served on the executive council of several of the premier surgical associations in the United States. Dr. Pawlik is a member of a number of professional societies including the Society of Surgical Oncology, the Americas Hepato-Pancreato-Biliary Association, Association for Academic Surgery, Society of Clinical Surgery, as well as the American Surgical Association.
In 2015, Dr. Pawlik was named an honorary fellow of the Royal Australia College of Surgeons, and an honorary member with the Brazilian Society of Surgical Oncology.
- Chief, Division of Surgical Oncology
- John L. Cameron M.D. Professor of Alimentary Tract Diseases
- Director, The Johns Hopkins Medicine Liver Tumor Center
- Professor of Surgery
- Professor of Oncology
- MD MPH, Tufts University School of Medicine (1995)
- University of Michigan Health System / General Surgery (2002)
- The University of Texas MD Anderson Cancer Center - GME / Oncology (2005)
- American Board of Surgery / General Surgery (2004)
- Johns Hopkins Bloomberg School of Public Health (Baltimore MD ) (2012)
Research & Publications
Selected PublicationsComparative effectiveness research, focus on hepatobiliary malignancies
Experimental therapeutics of hepatobiliary malignancies
Clinical trials in hepatobiliary malignancies
Assessing outcomes of emerging therapies for hepatobiliary malignancies
Decision-making around managing hepatobiliary malignancies
Pawlik TM, Assumpcao L, Vossen JA, Buijs M, Gleisner AL, Schulick RD, Choti MA. Trends in Non-Therapeutic Laparotomy Rates in Patients Undergoing Surgical Therapy for Hepatic Colorectal Metastases. Annals of Surgical Oncology. 16:371-378; 2008.
Asiyanbola B, Gleisner AL, Herman JM, Choti MA, Wolfgang CL, Edil BH, Schulick RD, Cameron CL, Pawlik TM. Determining Pattern of Recurrence Following Pancreaticoduodenectomy: Effect of Number of Metastatic Lymph Nodes and Lymph Node Ratio. Journal of Gastrointestinal Surgery. 13(4):752-759, 2009.
Pawlik TM. Debate: Resection for Early Hepatocellular Carcinoma. Journal of Gastrointestinal Surgery. 13(6):1026-1028, 2009.
Childers R, Lipsett PA, Pawlik TM. Informed Consent and the Surgeon. Journal of the American College of Surgeons. 208(4):627-634, 2009.
Jain A, Smith C, Geschwind JFH, Pawlik TM. Clinical Images: Gastrohepatic Fistula following Transarterial Chemoembolization for Hepatocellular Carcinoma. Archives of Surgery. 144:285-286; 2009.
Cunningham SC, Tsai S, Marques HP, Mira P, Cameron A, Barroso E, Philosophe B, Pawlik TM. Management of Early Hepatocellular Carcinoma in Patients with Well-Compensated Cirrhosis. Annals of Surgical Oncology. 16(7):1820-31; 2009.
Tsai S, Pawlik TM. Outcomes of Ablation versus Resection for Colorectal Metastases: Are We Comparing Apples to Oranges? Annals of Surgical Oncology. 16(9):2422-8; 2009.
Nathan H, Cameron JL, Choti MA, Schulick RD, Pawlik TM. The Volume-Outcome Effect in Hepato-Pancreato-Biliary Surgery: Hospital versus Surgeon Contributions and Specificity of the Relationship. Journal of the American College of Surgeons. 208(4):528-538, 2009.
Nathan H, Schulick RD, Choti MA, Pawlik TM. Predictors of Survival after Resection of Early Hepatocellular Carcinoma. Annals of Surgery. 249(5):799-805; 2009.
Mayo S, Pawlik TM. Current Management of Colorectal Metastasis. Expert Review of Gastroenterology & Hepatology. 3:131-144; 2009.
Pawlik TM, Hong SM, Cho H, Aggarwal B, Goggins M, Hruban RH, Anders RA. Depth of Tumor Invasion Better Predicts Prognosis than the Current AJCC T Classification for Distal Bile Duct Carcinoma. SURGERY. 146(2):250-257:2009.
Tsai S, Pawlik TM. Primary Sclerosing Cholangitis: The Role of Extrahepatic Biliary Resection. Advances in Surgery. 43:175-188, 2009.
Nathan H, Mentha G, Marques HP, Capussotti L, Majno P, Aldrighetti L, Pulitano C, Rubbia-Brandt L, Russolillo N, Philosophe B, Barroso E, Ferrero A, Schulick RD, Choti MA, Pawlik TM. Comparative Performance of Staging Systems for Early Hepatocellular Carcinoma. HPB. 11(5):382-90, 2009.
Hueman MT, Vollmer CM, Pawlik TM. Evolving Treatment Strategies for Gallbladder Cancer. Annals of Surgical Oncology. 16(8);2101-2115; 2009.
Reddy S, Wolfgang CL, Cameron JL, Eckhauser F, Choti MA, Schulick RD, Edil BH, Pawlik TM. Total Pancreatectomy for Pancreatic Adenocarcinoma: Evaluation of Morbidity and Long-Term Outcome. Annals of Surgery. 250(2):282-287; 2009.
Nathan H, Raut CP, Thornton K, Herman JM, Ahuja N, Schulick RD, Choti MA, Pawlik TM. Predictors of Survival after Resection of Retroperitoneal Sarcoma: a Population-Based Analysis and Critical Appraisal of the AJCC Staging System. Annals Surgery. 250(6):970-6; 2009.
Augustine MM, Pawlik TM. Palliation of Advanced Gastrointestinal Malignancies using Minimally-Invasive Strategies. Progress in Palliative Care. 17(5):250-260; 2009.
de Jong M, Pulitano C, Ribero D, Strub J, Mentha G, Schulick RD, Choti MA, Capussotti, Pawlik TM. Rates and Patterns of Recurrence Following Curative Intent Surgery for Colorectal Liver Metastases: an International Multi-Institutional Analysis of 1669 Patients. Annals of Surgery. 250(3);440-448; 2009.
de Jong MC, Mayo SC, Pulitano C, Ribero D, Strbu J, Hubert C, Gigot JF, Schulick RD, Choti MA, Aldrighetti L, Mentha G, Capussotti L, Pawlik TM. Repeat Curative Intent Liver Surgery is Safe and Effective for Recurrent Colorectal Liver Metastases: Results from an International Multi-Institutional Analysis. Journal of Gastrointestinal Surgery. 13(12):2141-2151;2009.
Pitt HA, Kilbane M, Strasberg SM, Pawlik TM, Dixon E, Zyromski NJ, Aloia TA, Henderson M, Mulvihill SJ. HPB NSQIP: Potential for Quality Improvement, Registries and Clinical Trials. HPB. 11(5):405-13; 2009.
Gleisner AL, Muoz A, Brandao A, Marroni C, Zanotelli ML, Cantisani GG, Moreira LB, Berton G, Marques H, Choti MA, Pawlik TM. Survival Benefit of Liver Transplantation and the Effect of Underlying Liver Disease. SURGERY. 147(3):392-404;2009.
Poultsides GA, Schulick RD, Pawlik TM. Hepatic Resection for Colorectal Metastases: the Impact of Surgical Margin Status on Outcome. HPB. 12(1);43-49;2010.
Brooke BS, Meguid RA, Makary MA, Perler BA, Pronovost PJ, Pawlik TM. Improving Surgical Outcomes through Adoption of Evidence-Based Process Measures: Intervention Specific or Associated with Overall Hospital Quality? SURGERY. 147(4):481-490;2010
Winter JM, Cameron JL, Olino K, Herman JM, Hruban RH, Wolfgang CL, Eckhauser F, Edil BH, Choti MA, Schulick, Pawlik TM. Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis. Journal of Gastrointestinal Surgery. 14(2):379-387;2010.
Hine K, Pawlik TM. Klatskin Cholangiocarinoma with Portal Vein Encasement. Journal of the American Academy of Physician Assistants. 23(1):30-32;2010.
Nathan H, de Jong MC, Pulitano C, Ribero D, Strub J, Mentha G, Gigot JF, Schulick RD, Choti MA, Aldrighetti L, Capussotti L, Pawlik TM. Conditional Survival Following Surgical Resection of Colorectal Liver Metastasis: An International Multi-Institutional Analysis of 949 Patients. Journal of the American College of Surgeons 210(5):755-764;2010.
Mayo S, Pawlik TM. Thermal Ablative Techniques for Secondary Hepatic Malignancies. The Cancer Journal. 16(2):111-117, 2010.
Tsai S, Gurakar A, Anders R, Lam-Himlin D, Boitnott J, Pawlik TM. Management of Large Hepatocellular Carcinoma in Adult Patient with Alagilles Syndrome. Digestive Diseases and Sciences. [Epub ahead of print] 2010.
Nathan H, Pawlik TM. Staging of Intrahepatic Cholangiocarinoma. Current Opinions in Gastroenterology. 26(3):269-273, 2010.
Tsai S, Choit MA, Assumpcao L, Cameron JL, Gleisner AL, Herman JM, Eckhauser F, Edil BH, Schulick RD, Wolfgang CL, Pawlik TM. Impact of Obesity on Peri-operative Outcomes and Survival Following Pancreaticoduodenectomy for Pancreatic Cancer: a Large Single Institution Study. Journal of Gastrointestinal Surgery. 14(7):1143-1150, 2010.
van Vledder MG, Pawlik TM, Munireddy S, Hamper U, de Jong MC, Choti MA. Factors Determining Sensitivity of Intraoperative Ultrasonography in Detecting Colorectal Liver Metastases in the Modern Era. Annals of Surgical Oncology. [Epub ahead of print] 2010.
De Jong MC, Farnell MB, Sclabas G, Cunningham SC, Cameron JL, Geschwind JF, Wolfgang CL, Herman JM, Edil BH, Choti MA, Schulick RD, Nagorney DM, Pawlik TM. Liver-Directed Therapy for Hepatic Metastases in Patients Undergoing Pancreaticoduodenectomy: a Dual-Center Analysis. Annals of Surgery. 252(1):142-148, 2010.
Poultsides GA, Zhu AX, Choti MA, Pawlik TM. Intra-hepatic Cholangiocarcinoma. Surgical Clinics of North America. [Epub ahead of print] 2010.
Tsai S, Marques HP, de Jong MC, Mira P, Ribeiro V, Choti MA, Schulick RD, Barroso E, Pawlik TM. Two-Stage Strategy for Patients with Extensive Bilateral Colorectal Liver Metastases. HPB. 12(4):262-269, 2010.
Mayo SC, Pawlik TM. Colorectal Hepatic Metastasis: Current Therapeutic Approach. (IN PRESS, European Gastroenterology and Hepatology)
de Jong MC, Tsai S, Cameron JL, Wolfgang CL, Hirose K, van Vledder MG, Eckhauser F, Edil BH, Choti MA, Schulick RD, Pawlik TM. Safety and Efficacy of Curative Intent Surgery for Peri-Ampullary Liver Metastasis. [Epub ahead of print] Journal of Surgical Oncology
Mayo SC, de Jong MC, Pulitano C, Clary BM, Reddy SK, Gamblin TC, Celinski SA, Kooby DA, Staley CA, Stokes JB, Chu CK, Ferrero A, Schulick RD, Choti MA, Mentha G, Strub J, Bauer TW, Adams RB, Aldrighetti L, Capussotti L, Pawlik TM. Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis. Annals of Surgical Oncology. [Epub ahead of print] Annals of Surgical Oncology 2010.
Vauthey JN, Dixon E, Abdalla EK, Helton WS, Pawlik TM, Taouli B, Brouquet A, Adams RB. Pretreatment Assessment of Hepatocellular Carcinoma: Expert Consensus Statement. HPB. 12(5):288-299, 2010.
Mayo SC, Shore AD, Nathan H, Edil B, Wolfgang CL, Hirose K, Herman J, Schulick RD, Choti MA, Pawlik TM. National Trends in the Management and Survival of Surgically Managed Gallbladder Adenocarcinoma Over 15 years: A Population-Based Analysis. (ACCEPTED, Journal of Gastrointestinal Surgery)
de Jong MC, Hong SM, Augustine MM, Goggins MG, Wolfgang CL, Hirose K, Schulick RD, Choti MA, Anders RA, Pawlik TM. Hilar Cholangiocarcinoma: Tumor Depth Predicts Outcome. (ACCETED, Archives of Surgery)
van Vledder MG, de Jong MC, Pawlik TM, Schulick RD, Diaz L, Choti MA. Disappearing Colorectal Liver Metastases after Chemotherapy: Should we be Concerned? (ACCEPTED, Journal of Gastrointestinal Surgery)
de Jong MC, van Vledder MG, Ribero D, Hubert C, Gigot JF, Choti MA, Schulick RD, Capussotti L, Dejong CH, Pawlik TM. Therapeutic Efficacy of Combined Intraoperative Ablation and Resection for Colorectal Liver Metastases. (ACCEPTED, Journal of Gastrointestinal Surgery)
Activities & Honors
- Chair, American College of Surgeons Oncology Group (ACOSOG) Constitution and By-Laws Committee
- Councilor-at-Large, Society of Surgical Oncology, Executive Council Committee
- Treasurer, Association for Academic Surgery
- Chair, Membership Committee, American Hepato-Pancreatico-Biliary Association (AHPBA)
- Traveling Fellowship Award, Japan Surgical Society
- International Traveling Faculty Award, Society for Surgery of the Alimentary Tract
- Award for Excellence in Medical Student Education in the Department of Surgery
- Honorary Fellowship Award, Royal Australasian College of Surgeons, 2015
- Honorary Fellow, Australia College of Surgeons
- Honorary Member, Brazilian Society of Surgical Oncology
- American College of Surgeons
- American Hepato-Pancreatico-Biliary Association
- American Society of Clinical Oncology
- Association for Academic Surgery
- International Hepato-Pancreatico-Biliary Association
- Pancreas Club
- Society for Surgery of the Alimentary Tract
- Society of Surgical Oncology
- Society of University Surgeons
- Surgical Biology Club II
Videos & Media
Liver Tumor Center Patient Story
Johns Hopkins Medicine Liver Cancer Patient Goes the Distance
Treatment Options for Liver Cancer and What to Expect
Johns Hopkins Surgical Oncologists Get Personal