Dr. Lange joined the faculty of Johns Hopkins in 1994 and subsequently earned a Sc.M. in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health. She focuses on the care of melanoma and breast cancer patients. Dr. Lange was one of the original members of the Johns Hopkins melanoma group when it was first formed in 1995 and now serves as a clinical co-director of the Melanoma Program. Dr. Lange introduced the sentinel node technique to Hopkins for both melanoma and breast cancer in the 1990s and has extensive experience with this technique. She has particular interest in melanoma at extremes of age, and the factors associated with variance in melanoma care. She has published the largest study of melanoma in children, adolescents and young adults. She recognizes that melanoma in the older patient is a growing epidemic and has investigated the socioeconomic, demographic and healthcare factors that influence the treatment of melanoma in older persons. She is a member of the melanoma panel of the National Comprehensive Cancer Network, a group that annually evaluates and revises national treatment guidelines for melanoma.