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Angelo Michael DeMarzo, M.D., Ph.D.

Associate Director of Cancer Research Pathology, SKCCC
Professor of Pathology


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Associate Director of Cancer Research Pathology, SKCCC
  • Director, Tissue Microarray Core Facility
  • Professor of Pathology
  • Professor of Oncology
  • Professor of Urology

Centers & Institutes


  • Oncology - Prostate Cancer/GU
  • Pathology - Kidney-Urologic Pathology
  • Urology


The Johns Hopkins Hospital

Appointment Phone: 410-614-5686

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map


Pathology, Prostate Cancer


Dr. Angelo De Marzo is a professor of pathology, oncology and urology at the Johns Hopkins School of Medicine. His areas of clinical expertise include pathology and prostate cancer. Dr. De Marzo serves as the associate director of Cancer Research Pathology at the Sidney Kimmel Comprehensive Cancer Center.

Dr. De Marzo founded the Tissue Microarray Core at Johns Hopkins, now known as the Oncology Tissue Services. He led it for a decade and now serves as an advisor to the core.

Dr. De Marzo's research interests include the molecular pathobiology of prostate cancer, biospecimen banking, biomarker development and tissue microarrays.

Dr. De Marzo received his B.A. in molecular, cellular and developmental biology and psychology from the University of Colorado at Boulder. He earned his M.D. and Ph.D. in experimental pathology from University of Colorado Health Sciences Center. He completed his residency in pathology at the Johns Hopkins School of Medicine and performed a fellowship at the Brady Urological Institute at Johns Hopkins. Dr. De Marzo joined the Johns Hopkins faculty in 1998.

Dr. De Marzo is Chief Medical Officer at Predictive Biosciences Inc., and serves on the editorial board of The Prostate and Cancer Prevention Research. He is the recipient of the 2004 Donald S. Coffey Prostate Cancer Foundation Physician/Scientist Award and is a member of various professional organizations, including the American Urological Association and the American Association for Cancer Research. more

    Additional Information

  • Education +


    • University of Colorado Health Sciences Center / MD (1994)


    • Johns Hopkins University School of Medicine / Pathology (1997)


    • Johns Hopkins University School of Medicine (1998)


    • American Board of Pathology / Anatomic Pathology (1998)
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Tan S, Sood A, Rahimi H, Wang W, Gupta N, Hicks J, Mosier S, Gocke CD, Epstein JI, Netto GJ, Liu W, Isaacs WB, De Marzo AM, Lotan T. "Rb Loss is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma." Clin Cancer Res. 2013 Dec 9. [Epub ahead of print]
    2. Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM. "Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli." PLoS One. 2013 Nov 27;8(11):e79842. doi: 10.1371/journal.pone.0079842. eCollection 2013.
    3. Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. "Telomere length as a risk factor for hereditary prostate cancer." Prostate. 2014 Apr;74(4):359-64. doi: 10.1002/pros.22755. Epub 2013 Nov 28.
    4. Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S. "Tracking the clonal origin of lethal prostate cancer." J Clin Invest. 2013 Nov 1;123(11):4918-22. doi: 10.1172/JCI70354. Epub 2013 Oct 25.
    5. Darshan M, Zheng Q, Fedor HL, Wyhs N, Yegnasubramanian S, Lee P, Melamed J, Netto GJ, Trock BJ, De Marzo AM, Sfanos KS. "Biobanking of derivatives from radical retropubic and robot-assisted laparoscopic prostatectomy tissues as part of the prostate cancer biorepository network." Prostate. 2014 Jan;74(1):61-9. doi: 10.1002/pros.22730. Epub 2013 Sep 21.
  • Academic Affiliations & Courses +
  • Activities & Honors +


    • Dean's List, University of Colorado, Boulder, 1982 - 1987
    • Alpha Omega Alpha (AOA) Society, 1993
    • Research and Clinical Fellowship, National Institutes of Health, Training Grant in Pathobiology of Cancer, 1997 - 1998
    • Harvey/Burroughs Welcome Clinician Scientist Award, The Johns Hopkins Medical Institutions, 1998
    • Mentored Clinician Scientist Development Award (K08), National Institutes of Health, National Cancer Institute, 1998
    • Stowell-Orbison Award for Research by a Pathologist-In-Training, International Academy of Pathology, 1998
    • Harvey/Burroughs Welcome Clinician Scientist Award, The Johns Hopkins Medical Institutions, 1999
    • Aegon Fellowship in Breast and Prostate Cancer Research, 2000
    • Achievement Award in Scientific Session: TMAJ, A Johns Hopkins Set of Open Source Software Tools to Manage a Multi-Organ, Scalable, Secure, Multi-User Tissue MicroArray Database., 2002 Meeting: Advancing Pathology Informatics, Imaging and the Internet, Pittsburgh, PA, 2002
    • Donald S. Coffey Prostate Cancer Foundation Physician/Scientist Award, 2004
    • STEP-UP Undergraduate Summer Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, 2007
    • Faculty Teaching Award, Department of Urology, 2008 - 2009
    • Teacher of the Year, Pathobiology Graduate Program, 2008


    • American Association for the Advancement of Science, 1987
    • American Medical Association, 1987 - 1994
    • Alpha Omega Alpha, 1993
    • American Society of Clinical Pathologists, 1995
    • College of American Pathologists, 1995
    • American Urological Association, 1998
    • American Association for Cancer Research, 2001

    Professional Activities

    • Chief Medical Officer, Predictive Biosciences Inc., 2012
  • Videos & Media +
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