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Derek Michael Fine, MD

Director, Nephrology Fellowship Program
Associate Professor of Medicine
Male
Appointment Phone

410-955-0670

Main Location

The Johns Hopkins Hospital

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Out-of-State & International Patients +
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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Nephrology Fellowship Program
  • Associate Professor of Medicine

Expertise

Glomerulonephritis, HIV Related Kidney Disease, Kidney biopsy, Lupus Nephritis, Nephrology, Rhabdomyolysis, Scleroderma Related Kidney Disease

Research Interests

Lupus nephritis; HIV kidney diseases

Languages

  • English
  • Afrikaans
Additional Resources +
  • Education +

    Training

    • Johns Hopkins University School of Medicine ( Baltimore MD) (1994)

    Residencies

    • Johns Hopkins University School of Medicine / Internal Medicine ( Baltimore MD) (1997)

    Fellowships

    • Johns Hopkins University School of Medicine / Nephrology ( Baltimore MD) (1999)

    Certifications

    • American Board of Internal Medicine / Nephrology (2010)
  • Research & Publications +

    Research Summary

    Dr. Fine’s research has predominantly focused on optimizing the diagnosis and management glomerular kidney diseases, particularly HIV- and SLE- related kidney disease.

    Selected Publications

    1. Gregory M Lucas; Yuezhou Jing; Mark Sulkowski; Alison G Abraham; Michelle M Estrella; Mohamed G Atta; Derek M Fine; Marina B Klein; Michael J Silverberg; M John Gill; et al. Hepatitis C viremia and the risk of chronic kidney disease in HIV-infected individuals. The Journal of infectious diseases 2013;208(8):1240-9. 2013 
    2. Matthew C Foy; Michelle M Estrella; Gregory M Lucas; Faryal Tahir; Derek M Fine; Richard D Moore; Mohamed G Atta; Comparison of risk factors and outcomes in HIV immune complex kidney disease and HIV-associated nephropathy. Clinical journal of the American Society of Nephrology : CJASN 2013;8(9):1524-32. 2013 
    3. Teresa K Chen; Derek M Fine; Top 10 developments in lupus nephritis. Current rheumatology reports 2013;15(9):358. 2013 
    4. Derek M Fine; Joel E Gallant; Nephrotoxicity of antiretroviral agents: is the list getting longer? The Journal of infectious diseases 2013;207(9):1349-51. 2013 
    5. Masahiro Ono; George J Arnaoutakis; Derek M Fine; Kenneth Brady; R Blaine Easley; Yueying Zheng; Charles Brown; Nevin M Katz; Morgan E Grams; Charles W Hogue; Blood pressure excursions below the cerebral autoregulation threshold during cardiac surgery are associated with acute kidney injury. Critical care medicine 2013;41(2):464-71. 2013
    6. Mohamed G Atta; Michelle M Estrella; Michael Kuperman; Matthew C Foy; Derek M Fine; Lorraine C Racusen; Gregory M Lucas; George W Nelson; Andrew C Warner; Cheryl A Winkler; et al. HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics. Kidney international 2012;82(3):338-43. 2012 
    7. T K Chen; M M Estrella; D M Fine; Predictors of kidney biopsy complication among patients with systemic lupus erythematosus. Lupus 2012;21(8):848-54. 2012 
    8. Matthew C Foy; Chloe L Thio; Hyon S Hwang; Melissa Saulynas; James P Hamilton; Derek M Fine; Mohamed G Atta; False-negative hepatitis B virus (HBV) surface antigen in a vaccinated dialysis patient with a high level of HBV DNA in the United States. Clinical and vaccine immunology : CVI 2012;19(5):820-2. 2012 
    9. Derek M Fine; Walter G Wasser; Michelle M Estrella; Mohamed G Atta; Michael Kuperman; Revital Shemer; Arun Rajasekaran; Shay Tzur; Lorraine C Racusen; Karl Skorecki; APOL1 risk variants predict histopathology and progression to ESRD in HIV-related kidney disease. Journal of the American Society of Nephrology : JASN 2012;23(2):343-50. 2012 
    10. Michelle M Estrella; Gregory D Kirk; Shruti H Mehta; Todd T Brown; Derek M Fine; Mohamed G Atta; Gregory M Lucas; Vitamin D deficiency and persistent proteinuria among HIV-infected and uninfected injection drug users. AIDS (London, England) 2012;26(3):295-302. 2012 
    11. Elizabeth George; Girish N Nadkarni; Michelle M Estrella; Gregory M Lucas; C John Sperati; Mohamed G Atta; Derek M Fine; The impact of hepatitis C coinfection on kidney disease related to human immunodeficiency virus (HIV): a biopsy study. Medicine 2011;90(5):289-95. 2011 
    12. Joel N Blankson; Christie R Basseth; Michael Kuperman; Derek M Fine; Spontaneous resolution of HIV-associated nephropathy in an elite controller. AIDS (London, England) 2011;25(8):1135-7. 2011 
    13. T Shafi; M J Choi; L C Racusen; L A Spacek; C Berry; M Atta; D M Fine; Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature. Clinical nephrology 2011;75 Suppl 1():60-4. 2011 
    14. Gregory M Lucas; William Clarke; Joseph Kagaayi; Mohamed G Atta; Derek M Fine; Oliver Laeyendecker; David Serwadda; Michael Chen; Maria J Wawer; Ronald H Gray; Decreased kidney function in a community-based cohort of HIV-Infected and HIV-negative individuals in Rakai, Uganda. Journal of acquired immune deficiency syndromes (1999) 2010;55(4):491-4. 2010 
    15. C M Lanata; T Mahmood; D M Fine; M Petri; Combination therapy of mycophenolate mofetil and tacrolimus in lupus nephritis. Lupus 2010;19(8):935-40. 2010 
    16. Joshua F Zeidner; Edwin J Ostrin; Emily Sydnor; Derek Fine; C John Sperati; The tissue's the issue. The American journal of medicine 2010;123(5):420-2. 2010 
    17. Shyam M Parkhie; Derek M Fine; Gregory M Lucas; Mohamed G Atta; Characteristics of patients with HIV and biopsy-proven acute interstitial nephritis. Clinical journal of the American Society of Nephrology : CJASN 2010;5(5):798-804. 2010 
    18. Elizabeth George; Gregory M Lucas; Girish N Nadkarni; Derek M Fine; Richard Moore; Mohamed G Atta; Kidney function and the risk of cardiovascular events in HIV-1-infected patients. AIDS (London, England) 2010;24(3):387-94. 2010 
    19. Derek M Fine; Mark A Perazella; Nephrogenic systemic fibrosis: what the hospitalist needs to know. Journal of hospital medicine : an official publication of the Society of Hospital Medicine 2010;5(1):46-50. 2010 
    20. Michelle M Estrella; Derek M Fine; Screening for chronic kidney disease in HIV-infected patients. Advances in chronic kidney disease 2010;17(1):26-35. 2010 
    21. Evan J Lipson; Carol Ann Huff; Danniele G Holanda; Michael A McDevitt; Derek M Fine; Lenalidomide-induced acute interstitial nephritis. The oncologist 2010;15(9):961-4. 2010 
    22. Derek M Fine; Martina Ziegenbein; Michelle Petri; Ernest C Han; Alison M McKinley; Jerry W Chellini; Haikady N Nagaraja; Kathryn A Carson; Brad H Rovin; A prospective study of protein excretion using short-interval timed urine collections in patients with lupus nephritis. Kidney international 2009;76(12):1284-8. 2009
    23. Sayed Tabatabai; C John Sperati; Mohamed G Atta; Kashif Janjua; Christopher Roxbury; Gregory M Lucas; Derek M Fine; Predictors of complication after percutaneous ultrasound-guided kidney biopsy in HIV-infected individuals: possible role of hepatitis C and HIV co-infection. Clinical journal of the American Society of Nephrology : CJASN 2009;4(11):1766-73. 2009 
    24. Kimberly Y Smith; Parul Patel; Derek Fine; Nicholaos Bellos; Louis Sloan; Philip Lackey; Princy N Kumar; Denise H Sutherland-Phillips; Cindy Vavro; Linda Yau; et al. Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/emtricitabine with lopinavir/ritonavir for initial HIV treatment. AIDS (London, England) 2009;23(12):1547-56. 2009 
    25. Mohamed G Atta; Derek M Fine; Editorial comment: tenofovir nephrotoxicity--the disconnect between clinical trials and real-world practice. The AIDS reader 2009;19(3):118-9. 2009 
    26. Javier Perez-Rodriguez; Shenghan Lai; Benjamin D Ehst; Derek M Fine; David A Bluemke; Nephrogenic systemic fibrosis: incidence, associations, and effect of risk factor assessment--report of 33 cases. Radiology 2009;250(2):371-7. 2009
    27. Derek M Fine; Agnes B Fogo; Charles E Alpers; Thrombotic microangiopathy and other glomerular disorders in the HIV-infected patient. Seminars in nephrology 2008;28(6):545-55. 2008 
    28. Michelle Petri; Nuntana Kasitanon; Sukminder Singh; Kimberly Link; Laurence Magder; Sang-Cheol Bae; John G Hanly; Ola Nived; Gunnar Sturfelt; Ronald van Vollenhoven; et al. Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal response. Arthritis and rheumatism 2008;58(6):1789-95. 2008 
    29. Michelle Petri; Nuntana Kasitanon; Shin-Seok Lee; Kimberly Link; Laurence Magder; Sang-Cheol Bae; John G Hanly; David A Isenberg; Ola Nived; Gunnar Sturfelt; et al. Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response index. Arthritis and rheumatism 2008;58(6):1784-8. 2008 
    30. Mohamed G Atta; Gregory M Lucas; Derek M Fine; HIV-associated nephropathy: epidemiology, pathogenesis, diagnosis and management. Expert review of anti-infective therapy 2008;6(3):365-71. 2008 
    31. Gregory M Lucas; Bryan Lau; Mohamed G Atta; Derek M Fine; Jeanne Keruly; Richard D Moore; Chronic kidney disease incidence, and progression to end-stage renal disease, in HIV-infected individuals: a tale of two races. The Journal of infectious diseases 2008;197(11):1548-57. 2008 
    32. Derek M Fine; Mark A Perazella; Gregory M Lucas; Mohamed G Atta; Kidney biopsy in HIV: beyond HIV-associated nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation 2008;51(3):504-14. 2008 
    33. Douglas R Linfert; Jane O Schell; Derek M Fine; Treatment of nephrogenic systemic fibrosis: limited options but hope for the future. Seminars in dialysis 2008;21(2):155-9. 2008
    34. Mark J Siedner; Mohamed G Atta; Gregory M Lucas; Mark A Perazella; Derek M Fine; Poor validity of urine dipstick as a screening tool for proteinuria in HIV-positive patients. Journal of acquired immune deficiency syndromes (1999) 2008;47(2):261-3. 2008 
    35. Derek M Fine; Mark A Perazella; Gregory M Lucas; Mohamed G Atta; Renal disease in patients with HIV infection: epidemiology, pathogenesis and management. Drugs 2008;68(7):963-80. 2008 
    36. Mark J Siedner; Allan C Gelber; Brad H Rovin; Alison M McKinley; Lisa Christopher-Stine; Brad Astor; Michelle Petri; Derek M Fine; Diagnostic accuracy study of urine dipstick in relation to 24-hour measurement as a screening tool for proteinuria in lupus nephritis. The Journal of rheumatology 2008;35(1):84-90. 2008 
    37. N Kasitanon; M Petri; M Haas; L S Magder; D M Fine; Mycophenolate mofetil as the primary treatment of membranous lupus nephritis with and without concurrent proliferative disease: a retrospective study of 29 cases. Lupus 2008;17(1):40-5. 2008 
    38. Adam R Berliner; Derek M Fine; Gregory M Lucas; M Hafizur Rahman; Lorraine C Racusen; Paul J Scheel; Mohamed G Atta; Observations on a cohort of HIV-infected patients undergoing native renal biopsy. American journal of nephrology 2008;28(3):478-86. 2008 
    39. Mohamed G Atta; Derek M Fine; Gregory D Kirk; Shruti H Mehta; Richard D Moore; Gregory M Lucas; Survival during renal replacement therapy among African Americans infected with HIV type 1 in urban Baltimore, Maryland. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(12):1625-32. 2007 
    40. Derek M Fine; Mohamed G Atta; Kidney disease in the HIV-infected patient. AIDS patient care and STDs 2007;21(11):813-24. 2007 
    41. Derek M Fine; Neha Garg; Mark Haas; M Hafizur Rahman; Gregory M Lucas; Paul J Scheel; Mohamed G Atta; Cocaine use and hypertensive renal changes in HIV-infected individuals. Clinical journal of the American Society of Nephrology : CJASN 2007;2(6):1125-30. 2007 
    42. Alexandre Benjo; Richard E Thompson; Derek Fine; Charles W Hogue; Diane Alejo; Anita Kaw; Gary Gerstenblith; Ashish Shah; Dan E Berkowitz; Daniel Nyhan; Pulse pressure is an age-independent predictor of stroke development after cardiac surgery. Hypertension 2007;50(4):630-5. 2007 
    43. Derek M Fine; Editorial comment: Fanconi syndrome and tenofovir--understanding proximal tubular function. The AIDS reader 2007;17(6):326-7. 2007 
    44. Mark J Siedner; Lisa Christopher-Stine; Brad C Astor; Allan C Gelber; Derek M Fine; Screening for proteinuria in patients with lupus: a survey of practice preferences among American rheumatologists. The Journal of rheumatology 2007;34(5):973-7. 2007 
    45. Lisa Christopher-Stine; Mark Siedner; Janice Lin; Mark Haas; Hemal Parekh; Michelle Petri; Derek M Fine; Renal biopsy in lupus patients with low levels of proteinuria. The Journal of rheumatology 2007;34(2):332-5. 2007 
    46. Julia J Scialla; Mohamed G Atta; Derek M Fine; Relapse of HIV-associated nephropathy after discontinuing highly active antiretroviral therapy. AIDS (London, England) 2007;21(2):263-4. 2007 
    47. N Kasitanon; D M Fine; M Haas; L S Magder; M Petri; Estimating renal function in lupus nephritis: comparison of the Modification of Diet in Renal Disease and Cockcroft Gault equations. Lupus 2007;16(11):887-95. 2007 
    48. Derek M Fine; Renal disease and toxicities: issues for HIV care providers. Topics in HIV medicine : a publication of the International AIDS Society, USA 2006;14(5):164-9. 2006 
    49. Mohamed G Atta; Joel E Gallant; M Hafizur Rahman; Nagapradeep Nagajothi; Lorraine C Racusen; Paul J Scheel; Derek M Fine; Antiretroviral therapy in the treatment of HIV-associated nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(10):2809-13. 2006 
    50. Michelle Estrella; Derek M Fine; Joel E Gallant; M Hafizur Rahman; Nagapradeep Nagajothi; Lorraine C Racusen; Paul J Scheel; Mohamed G Atta; HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(3):377-80. 2006 
    51. Geoffrey R Bihl; Michelle Petri; Derek M Fine; Kidney biopsy in lupus nephritis: look before you leap. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(7):1749-52. 2006 
    52. Hyun S Kim; Derek M Fine; Mohamed G Atta; Catheter-directed thrombectomy and thrombolysis for acute renal vein thrombosis. Journal of vascular and interventional radiology : JVIR 2006;17(5):815-22. 2006 
    53. N Kasitanon; D M Fine; M Haas; L S Magder; M Petri; Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis. Lupus 2006;15(6):366-70. 2006 
    54. Mohamed G Atta; Michael J Choi; J Craig Longenecker; Megan Haymart; Jean Wu; Nagapradeep Nagajothi; Lorraine C Racusen; Paul J Scheel; Frederick L Brancati; Derek M Fine; Nephrotic range proteinuria and CD4 count as noninvasive indicators of HIV-associated nephropathy. The American journal of medicine 2005;118(11):1288. 2005 
    55. Derek M Fine; Editorial comment: tenofovir nephrotoxicity--vigilance required. The AIDS reader 2005;15(7):362-3. 2005 
    56. Derek M Fine; Pharmacological therapy of lupus nephritis. JAMA : the journal of the American Medical Association 2005;293(24):3053-60. 2005 
    57. Gürkan Sengoelge; Wensheng Luo; Derek Fine; Agnes M Perschl; Wolfgang Fierlbeck; Abdolreza Haririan; Jenny Sorensson; Tausif-Ur Rehman; Peter Hauser; Jacob S Trevick; et al. A SAGE-based comparison between glomerular and aortic endothelial cells. American journal of physiology. Renal physiology 2005;288(6):F1290-300. 2005 
    58. N Dasgupta; A C Gelber; F Racke; D M Fine; Central nervous system lymphoma associated with mycophenolate mofetil in lupus nephritis. Lupus 2005;14(11):910-3. 2005 
    59. Derek M Fine; Allan C Gelber; Michal L Melamed; Janice C Lin; Lin Zhang; Joseph A Eustace; Risk factors for renal failure among 72 consecutive patients with rhabdomyolysis related to illicit drug use. The American journal of medicine 2004;117(8):607-10. 2004 
    60. Davinder S Grover; Mohamed G Atta; Joseph A Eustace; Thomas S Kickler; Derek M Fine; Lack of clinical utility of urine myoglobin detection by microconcentrator ultrafiltration in the diagnosis of rhabdomyolysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(10):2634-8. 2004 
    61. Lisa Christopher-Stine; Michelle Petri; Brad C Astor; Derek Fine; Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis. The Journal of rheumatology 2004;31(8):1557-9. 2004 
    62. Derek M Fine; Aravind Arepally; Lawrence V Hofmann; Steven G Mankowitz; Mohamed G Atta; Diagnostic utility and safety of transjugular kidney biopsy in the obese patient. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(7):1798-802. 2004 
    63. Allan C Gelber; Lisa Christopher-Stine; Derek M Fine; Sequential therapies for proliferative lupus nephritis. The New England journal of medicine 2004;350(24):2518-20; author reply 2518-20. 2004 
    64. Mohamed G Atta; J Craig Longenecker; Derek M Fine; Nagapradeep Nagajothi; Davinder S Grover; Jean Wu; Lorraine C Racusen; Paul J Scheel; Ulrike M Hamper; Sonography as a predictor of human immunodeficiency virus-associated nephropathy. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2004;23(5):603-10; quiz 612-3. 2004 
    65. Kyrsten D Fairbanks; Joseph A Eustace; Derek Fine; Paul J Thuluvath; Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(10):1079-85. 2003 
    66. Attaphol Pawarode; Derek M Fine; Paul J Thuluvath; Independent risk factors and natural history of renal dysfunction in liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(7):741-7. 2003 
    67. D M Fine; C F Lo; L Aguillar; D L Blackmon; M H Montrose; Cellular chloride depletion inhibits cAMP-activated electrogenic chloride fluxes in HT29-18-C1 cells. The Journal of membrane biology 1995;145(2):129-41. 1995 
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    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410-955-0670
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    Department/Division

    • Medicine - Nephrology

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