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Photo of Dr. William Sharfman

William H Sharfman, M.D.

Director, Cutaneous Oncology
Associate Professor of Oncology
Specializes In: Adults (18+ years)


Appointment Phone


Main Location

Johns Hopkins Medicine - Green Spring Station

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Director, Cutaneous Oncology
  • Clinical Co-Director for Oncology, Johns Hopkins Melanoma Program
  • Associate Professor of Oncology
  • Associate Professor of Dermatology

Centers & Institutes



Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-616-7660

Green Spring Station
10753 Falls Road
Pavilion II
Baltimore, MD 21093 map
Phone: 410-583-2970
Fax: 410-583-2980


Cutaneous Oncology, Dermatology, Gastrointestinal Cancers, Immunotherapy, Lung Cancer, Melanoma, Merkel Cell Carcinoma, Neuroendocrine Tumors

Research Interests

Novel therapies for high risk and advanced melanoma patients; GI Cancers; Lung Cancer


Dr. William H. Sharfman is an associate professor of oncology and dermatology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include cutaneous oncology, dermatology, gastrointestinal cancers and immunotherapy. He helped create the well-established Melanoma Program at Johns Hopkins in 1994. Dr. Sharfman serves as the director of cutaneous oncology and clinical co-director for oncology at the Johns Hopkins Melanoma Program.

He earned his M.D. from the University of Toledo College of Medicine. He completed his residency at Cleveland Clinic and performed a fellowship in hematology and oncology at Cleveland Clinic.

Dr. Sharfman's research interests include novel therapies for high risk and advanced melanoma patients; GI cancers; and lung cancer. more

    Additional Information

  • Education +


    • University of Toledo College of Medicine / MD (1982)


    • Cleveland Clinic / Internal Medicine (1985)


    • Cleveland Clinic / Hematology and Oncology (1989)


    • American Board of Internal Medicine / Hematology (1992, 2012)
    • American Board of Internal Medicine / Internal Medicine (1986)
    • American Board of Internal Medicine / Medical Oncology (1989)
  • Research & Publications +

    Research Summary

    Dr. Sharfman’s research focuses on melanoma, including novel therapies for advanced melanoma patients.

    Selected Publications

    1. Lange, J.R.; Fecher, L.; Sharfman, W.H.; Alani, R.M.; Mikkilineni, R.; Topalian, S.L.; Balch, C.M. Melanoma. In: Abeloff MD, A.J., Niederhuber JE, Kastan MB, McKenna WG editor. 4th ed, Abeloffs Clinical Oncology. Philadelphia: Elsevier Inc.; 2008. p. 1229-1252.
    2. Brahmer, J.R.; Drake, C.G.; Wollner, I.; Powderly, J.D.; Picus, J.; Sharfman, W.H.; Stankevich, E.; Pons, A.; Salay, T.M.; McMiller, T.L.; Gilson, M.M.; Wang, C.; Selby, M.; Taube, J.M.; Anders, R.; Chen, L.; Korman, A.J.; Pardoll, D.M.; Lowy, I.; Topalian, S.L. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010 Jul 1;28(19):3167-3175.
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +

    Lectures and Presentations

    Skin Cancer 101 with an Emphasis on Melanoma

    Recent News Articles & Media Coverage

    Two Regattas,” The New York Times, December 24, 2008

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