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Lawrence J Cheskin, MD

Director, Johns Hopkins Weight Management Center

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Johns Hopkins Weight Management Center

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  • Director, Johns Hopkins Weight Management Center

Centers & Institutes

  • Global mHealth Initiative
  • Global Obesity Prevention Center
  • Metabolism and Obesity Research, Center for
  • Weight Management Center


Gastroenterology, Obesity, Weight Management

Research Interests

weight control; obesity

Technology Expertise



Lawrence J. Cheskin, MD  directs the Johns Hopkins Weight Management Center, a multidisciplinary clinical research and treatment program that he founded in 1990. He is Associate Professor of Health, Behavior & Society at the School of Public Health, with joint appointments in International Health (Human Nutrition), in Medicine (Gastroenterology) at the School of Medicine, and in Public Health Studies at Homewood. He is also Co-Associate Director of the Johns Hopkins Global Center on Childhood Obesity.

 In his research, Dr. Cheskin studies the effectiveness of various lifestyle and dietary changes in weight loss and weight maintenance.  He has experience in design and implementation of controlled clinical trials and laboratory studies of different diet techniques, as well as individual and community-based interventions, including among underserved residents of inner-city Baltimore and suburban Baltimore.  His background and experience is broad, ranging from basic science work on dopamine genetics, to work on preventing childhood obesity through the Johns Hopkins Global Center on Childhood Obesity, where he also directs the Rapid Response Project Core, which evaluates timely systems-focused proposals worldwide to study such areas as school policies and the built environment’s effect on factors relevant to preventing childhood obesity.  He has 110 peer reviewed publications, has written 6 books, and is frequently cited in the media on issues related to obesity and dieting.


  • English

Clinical Trial Keywords

  • obesity
  • behavior modification
  • exercise
  • diet
  • diabetes
  • nutrition
Additional Resources +
  • Education +


    • Dartmouth Medical School - Registrar's Office 7090 (Lebanon NH ) (1980)


    • New York Medical College / Internal Medicine (Valhalla NY ) (1983)


    • Yale - New Haven Hospital / Gastroenterology and Hepatology (New Haven CT ) (1986)


    • Internal Medicine, American Board of Internal Medicine (1985)
  • Research & Publications +

    Selected Publications View all on PubMed

    Cheskin LJ, *Davis LM, *Mitola AH, *Lipsky LM, *Lycan T, *Mitchell V, *Mickle B, *Adkins E. Lack of energy compensation over 4 days when white button mushrooms are substituted for beef. Appetite 51:50-57, 2008.

    *DavisLM, Michaelides M, Cheskin LJ, Moran TH, Aja S, Watkins PA, Pei Z, Contoreggi C, McCullough K, Hope B, Wang GJ, Volkow ND, Thanos PK. Bromocriptine administration reduces hyperphagia and adiposity in (fa/fa) Zucker and diet-induced obese rats and is associated with dopamine (DA) D2 receptor (D2R) and DA transporter (DAT) levels. Neuroendocrinology 89(2):152-62, 2009.

    Cheskin LJ, Mitchell AM, *Jhaveri AD, *Mitola AH, *Davis LM, Lewis RA, Yep MA, *Lycan TW. Efficacy of meal replacements versus standard food-based diet for weight loss in type 2 diabetes: A controlled clinical trial. The Diabetes Educator 34(1):118-127, 2008.

    Cheskin LJ, Gittelsohn J. In Focus: The Obesity Epidemic. Obesity as a future healthcare nightmare: Can health policy provide the cure? Harvard Health Policy Rev 4(2):56-61, 2003.

    ^Chen X, Cheskin LJ, Shi L, Wang Y. Americans with diet-related chronic diseases report higher diet quality than those without these diseases. Journal of Nutrition 141(8):1543-51, 2011. PMID: 21697303

    The Look AHEAD Research Group. Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care. 2011 Oct;34(10):2152-7. PMID:21836103

     Poddar K, *Kolge S, Bezman L, Mullin GE, Cheskin LJ. Nutraceutical supplements for weight loss: A systematic review. Nutrition in Clinical Practice, 26(5): 539- 52, 2011.DOI 10.1177/0884533611419859

     The Look AHEAD Research Group. Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity. 2011 Oct;19(10):1987-98. PMID:21779086

     Cheskin LJ, Sansone CM, Davis LM. Clinical strategies for managing the overweight neurology patient. Neurology: Clin Prac 2012 March; 2(1): 33-39. doi: 10.1212/CPJ.0b013e31824c6ccd

     McCaffery JM, Papandonatos GD, Peter I, Huggins GS, Raynor HA, Delahanty LM, Cheskin LJ, Balasubramayan A, Wagenecht LE, Wing RR. Obesity susceptibility loci and dietary intake in the Look AHEAD trial. Am J Clin Nutr 2012;95 1477-1486, 2012.

     The Look AHEAD Research Group. Factors influencing enrollment of African-Americans in the Look AHEAD trial. Clin Trials. 2012 Feb;9(1):80-9. Epub 2011 Nov 7.PMID:22064686

     *Kumar AA, *Palamaner Subash Shantha G, Kahan S, *Samson RJ, *Boddu ND, Cheskin LJ. Intentional weight loss and dose reductions of anti-diabetic medications: a retrospective cohort study. PLoS ONE. 2012;7(2):e32395.

     *Palamaner Subash Shantha G, *Kumar AA, Kahan S, Cheskin LJ. Association between glycosylated hemoglobin and intentional weight loss in overweight and obese patients with type 2 diabetes: a retrospective cohort study. Diabetes Educator 2012 May-Jun;38(3):417-26, 2012.

     The Look AHEAD Research Group. One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Obesity. 2012 Apr;20(4):783-93 .PMID:22016099

     Frattaroli S, Pollack K, Cheskin LJ, Schaefer H, Bailey M, Holtgrave D. Working inside the firehouse: developing a participant-driven intervention to enhance health-promoting behaviors. Health Promotion Practice. 14(3): 451-458, 2013. DOI: 10.1177/1524839912461150.

     *Menez S, Cheskin L, Geller G. Perspectives on Obesity and Its Treatment: Health Care Providers and the General Public in Rural West Virginia and Urban Baltimore. DOI: 10.1177/1090198112473101. Health Education & Behavior, 40: 2013.

     *Palamaner Subash Shantha G, Kumar AA, Kahan S, Cheskin LJ. Intentional weight loss and dose reductions of anti-hypertensive medications: a retrospective cohort study.CardioRenal Medicine,Apr;3(1):17-25. 2013. doi: 10.1159/000347048. PMID:23946722

     Showell NN, Fawole O, Segal J, Wilson RF, Cheskin LJ, Bleich SN, Wu Y, Lau B, Wang Y. A systematic review of home-based childhood obesity prevention studies. Pediatrics, 131: 2013. PMID: 23753095

     *Poddar K, Ames MI, Chen HJ, Wang Y, Cheskin LJ. Positive effect of mushrooms substituted for meat on body weight, body composition, and health parameters - A one-year randomized clinical trial. Appetite, online 19 Sept 2013, ISSN 0195-6663,;

     *Palamaner Subash Shantha G, Kumar AA, Kahan S, Cheskin LJ. Triglyceride/HDL ratio as a screening tool for predicting success at reducing anti-diabetic medications following weight loss. PLoS ONE, Jul 15;8(7):e69285. doi: 10.1371/journal.pone.0069285, 2013. PMID:23869240.

    Hsieu S, Klassen AC, Caulfield LE, Curriero FC, Sprutz-Metz C, Cheskin LJ, Are fast food restaurant and park access related to insulin resistance among Hispanic youth?, Am J Preventive Medicine, in press, 2014.


    Clinical Trials

    Look AHEAD

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    Fellow of the American College of Physicians (FACP)

    Fellow, the Obesity Society (FTOS)

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  • Contact & Locations +


    Johns Hopkins Weight Management Center
    550 N. Broadway, Suite 1001
    Baltimore, MD 21205
    Phone: 410-502-0145
    Appointment Phone: 410-502-0145
    Fax: 410-502-6719
    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410-502-0145
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