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Nita Ahuja, MD

Director of Sarcoma and Peritoneal Surface Malignancy Program
Associate Professor of Surgery
Appointment Phone


Main Location

The Johns Hopkins Hospital

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Out-of-State & International Patients +
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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Director of Sarcoma and Peritoneal Surface Malignancy Program
  • Chief, Mixed Tumor Services
  • Associate Professor of Surgery
  • Associate Professor of Oncology
  • Associate Professor of Urology

Centers & Institutes

  • Colon Cancer Center
  • Gastric Cancer Center
  • Gastroenterology and Nutrition Center
  • Sidney Kimmel Comprehensive Cancer Center


Colorectal Cancer, Cytoreductive Surgery, Gastric Cancer, Gastroesophageal Cancer, Gastroesophageal Junction Cancer, Gastrointestinal Cancers, General Surgery, GIST, Intraperitoneal Chemotherapy, Neuroendocrine Tumors, Pancreatic Cancer, Retroperitoneal Sarcomas, Sarcoma, Stomach Cancer, Stomach Tumors, Whipple Procedure

Research Interests

Prognostic molecular markers in early detection and prognosis of cancers; Early detection of cancers using novel biomarkers; Identification of molecular profiles for recurrence of early-stage colorectal cancers; Epigenetic therapy for metastatic colorectal cancer


Dr. Nita Ahuja is an associate professor of urology, surgery and oncology at the Johns Hopkins School of Medicine. Her surgical specialization is in gastrointestinal cancers, including gastric, rectal and pancreatic cancers.

Dr. Ahuja serves as the Director of Sarcoma and Peritoneal Surface Malignancy Program and the Chief of Mixed Tumor Services.

Dr. Ahuja obtained her medical education at the Duke University School of Medicine and her training in general surgery at Johns Hopkins. In addition, she completed a fellowship in surgical oncology at Johns Hopkins focused on hepatobiliary malignancies. Dr. Ahuja joined the Johns Hopkins faculty in 2003.

Dr. Ahuja also directs an active cancer research laboratory studying molecular markers important in early diagnosis and prognosis of gastrointestinal cancer.

Dr. Ahuja was certified in surgery by the American Board of Surgery in 2003.


  • English

Additional Resources

Additional Resources +
  • Education +


    • Duke University School of Medicine (Durham NC ) (1993)


    • Johns Hopkins University School of Medicine / Surgery (Baltimore MD ) (2002)


    • Surgery, American Board of Surgery (2003)
  • Research & Publications +

    Research Summary

    Dr. Ahuja's research is focused on the role of DNA methylation in tumorigenesis and exploring the translational potential of these methylation changes. Current studies in the laboratory include the development of biomarkers for early detection of cancer and to predict recurrence in breast and colorectal cancers. Her laboratory has shown that DNA methylation changes can be used in stool DNA as a very sensitive and specific marker for early detection of colorectal cancer.

    The laboratory is focused on the development of markers for early detection of cancer using serum. In addition, the laboratory has an interest in studying inflammatory bowel disease associated cancers and has a large tissue bank in collaboration with the surgical specialists who treat these conditions. The laboratory is developing epigenetic therapies for gastrointestinal malignancies and has an ongoing phase II trial in the treatment of metastatic colorectal cancers. Dr. Ahuja's laboratory works in close collaborations with Drs. Stephen Baylin and James Herman in the Division of Tumor Biology in the Cancer Center as a multidisciplinary team.

    Selected Publications

    1. Downing, S.R.; Datoo, G.; Oyetunji, T.A.; Fullum, T.; Chang, D.C.; Ahuja, N. “Asian race/ethnicity as a risk factor for bile duct injury during cholecystectomy.” Arch Surg. 2010 Aug;145(8):785-787.
    2. Hayanga, A.J.; Mukherjee, D.; Chang, D.; Kaiser, H.; Lee, T.; Gearhart, S.; Ahuja, N.; Freischlag, J. “Teaching hospital status and operative mortality in the United States: tipping point in the volume-outcome relationship following colon resections?” Arch Surg. 2010 Apr;145(4):346-350
    3. Poultsides, G.A.; Reddy, S.; Cameron, J.L.; Hruban, R.H.; Pawlik, T.M.; Ahuja, N.; Jain, A.; Edil, B.H.; Iacobuzio-Donahue, C.A.; Schulick, R.D.; Wolfgang, C.L. “Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreas.” Ann Surg. 2010 Mar;251(3):470-476.
    4. Stojadinovic, A.; Ahuja, N.; Nazarian, S.M.; Segev, D.L.; Jacobs, L.; Wang, Y.; Eberhardt, J.; Zeiger, M.A. “Translational research in surgical disease.” Arch Surg. 2010 Feb;145(2):187-196.
    5. van Vlodrop, I.J.; Baldewijns, M.M.; Smits, K.M.; Schouten, L.J.; van Neste, L.; van Criekinge, W.; van Poppel, H.; Lerut, E.; Schuebel, K.E.; Ahuja, N.; Herman, J.G.; de Bruine, A.P.; van Engeland, M. “Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.” Am J Pathol. 2010 Feb;176(2):575-584.

    Clinical Trials

    Partial Breast Irradiation With Concurrent Chemotherapy for Women With Breast Cancer (PBI 3)

  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +


    Johns Hopkins Surgical Oncologists Get Personal

    The surgical oncology team at Johns Hopkins gets personal as they speak about their role in treating their patients and what the Promise of Medicine means to them.

    Surgical Oncologist, Nita Ahuja, M.D. Discusses Sarcoma

    Meet Johns Hopkins surgical oncologist, Nita Ahuja, M.D., and hear her discuss sarcoma treatment options including surgery.

    Importance of Sarcoma Surgery Done Right The First Time

    Johns Hopkins surgical oncologist, Nita Ahuja, M.D., discusses the importance of having sarcoma surgery done right the first time.

  • Events +
  • Contact & Locations +


    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-955-5020
    Appointment Phone: 443-997-1508
    Fax: 443-451-8583
    Location Map


    • Surgery - Surgical Oncology

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