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Nita Ahuja, M.D.

Director of Sarcoma and Peritoneal Surface Malignancy Program
Associate Professor of Surgery

Female

Appointment Phone

443-997-1508

Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director of Sarcoma and Peritoneal Surface Malignancy Program
  • Chief, Mixed Tumor Services
  • Associate Professor of Surgery
  • Associate Professor of Oncology
  • Associate Professor of Urology

Centers & Institutes

Departments

  • Oncology - Cancer Biology
  • Surgery - Surgical Oncology
  • Urology

Locations

The Johns Hopkins Hospital

Appointment Phone: 443-997-1508

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-5020
Fax: 443-451-8583

Expertise

Colorectal Cancer, Cytoreductive Surgery, Gastric Cancer, Gastroesophageal Cancer, Gastroesophageal Junction Cancer, Gastrointestinal Cancers, General Surgery, GIST, Intraperitoneal Chemotherapy, Neuroendocrine Tumors, Pancreatic Cancer, Retroperitoneal Sarcomas, Sarcoma, Stomach Cancer, Stomach Tumors, Whipple Procedure

Research Interests

Early detection of cancers using novel biomarkers; Prognostic molecular markers in early detection and prognosis of cancers; Identification of molecular profiles for recurrence of early-stage colorectal cancers; Epigenetic therapy for metastatic colorectal cancer

Biography

Dr. Nita Ahuja is an associate professor of urology, surgery and oncology at the Johns Hopkins School of Medicine. Her surgical specialization is in gastrointestinal cancers, including gastric, rectal and pancreatic cancers.

Dr. Ahuja serves as the Director of Sarcoma and Peritoneal Surface Malignancy Program and the Chief of Mixed Tumor Services.

Dr. Ahuja obtained her medical education at the Duke University School of Medicine and her training in general surgery at Johns Hopkins. In addition, she completed a fellowship in surgical oncology at Johns Hopkins focused on hepatobiliary malignancies. Dr. Ahuja joined the Johns Hopkins faculty in 2003.

Dr. Ahuja also directs an active cancer research laboratory studying molecular markers important in early diagnosis and prognosis of gastrointestinal cancer.

Dr. Ahuja was certified in surgery by the American Board of Surgery in 2003.

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    Additional Information

  • Education +

    Degrees

    • Duke University School of Medicine / MD (1993)

    Residencies

    • Johns Hopkins University School of Medicine / Surgery (2002)

    Certifications

    • American Board of Surgery / Surgery (2003, 2024)
  • Research & Publications +

    Research Summary

    Dr. Ahuja's research is focused on the role of DNA methylation in tumorigenesis and exploring the translational potential of these methylation changes. Current studies in the laboratory include the development of biomarkers for early detection of cancer and to predict recurrence in breast and colorectal cancers. Her laboratory has shown that DNA methylation changes can be used in stool DNA as a very sensitive and specific marker for early detection of colorectal cancer.

    The laboratory is focused on the development of markers for early detection of cancer using serum. In addition, the laboratory has an interest in studying inflammatory bowel disease associated cancers and has a large tissue bank in collaboration with the surgical specialists who treat these conditions. The laboratory is developing epigenetic therapies for gastrointestinal malignancies and has an ongoing phase II trial in the treatment of metastatic colorectal cancers. Dr. Ahuja's laboratory works in close collaborations with Drs. Stephen Baylin and James Herman in the Division of Tumor Biology in the Cancer Center as a multidisciplinary team.

    Clinical Trials:

    Partial Breast Irradiation With Concurrent Chemotherapy for Women With Breast Cancer (PBI 3)


    Selected Publications

    1. Downing, S.R.; Datoo, G.; Oyetunji, T.A.; Fullum, T.; Chang, D.C.; Ahuja, N. "Asian race/ethnicity as a risk factor for bile duct injury during cholecystectomy." Arch Surg. 2010 Aug;145(8):785-787.
    2. Hayanga, A.J.; Mukherjee, D.; Chang, D.; Kaiser, H.; Lee, T.; Gearhart, S.; Ahuja, N.; Freischlag, J. "Teaching hospital status and operative mortality in the United States: tipping point in the volume-outcome relationship following colon resections?" Arch Surg. 2010 Apr;145(4):346-350
    3. Poultsides, G.A.; Reddy, S.; Cameron, J.L.; Hruban, R.H.; Pawlik, T.M.; Ahuja, N.; Jain, A.; Edil, B.H.; Iacobuzio-Donahue, C.A.; Schulick, R.D.; Wolfgang, C.L. "Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreas." Ann Surg. 2010 Mar;251(3):470-476.
    4. Stojadinovic, A.; Ahuja, N.; Nazarian, S.M.; Segev, D.L.; Jacobs, L.; Wang, Y.; Eberhardt, J.; Zeiger, M.A. "Translational research in surgical disease." Arch Surg. 2010 Feb;145(2):187-196.
    5. van Vlodrop, I.J.; Baldewijns, M.M.; Smits, K.M.; Schouten, L.J.; van Neste, L.; van Criekinge, W.; van Poppel, H.; Lerut, E.; Schuebel, K.E.; Ahuja, N.; Herman, J.G.; de Bruine, A.P.; van Engeland, M. "Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma." Am J Pathol. 2010 Feb;176(2):575-584.
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    • $50,000 grant, from Abell Foundation for development of blood test for early detection of pancreatic cancer , 2014
  • Videos & Media +

    Videos

    Surgical Oncologist, Nita Ahuja, M.D. Discusses Sarcoma

    Importance of Sarcoma Surgery Done Right The First Time

    Sarcoma Treatment | Nora's Story

    Sarcoma (Soft Tissue Cancer) Treatment | Nora's Story (Extended version)

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