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Photo of Dr. Edward S Chen, M.D.

Edward S Chen, M.D.

Assistant Professor of Medicine

Male  | Languages: English, Chinese, Mandarin

Appointment Phone


Main Location

Johns Hopkins Bayview Medical Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Assistant Professor of Medicine



Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864

5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-3467

601 N. Caroline Street
Baltimore, MD 21287 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-2280

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map


Emergency Medicine, Pulmonary Medicine, Sarcoidosis

Research Interests

Granulomatous inflammation; Bleomycin induced pulmonary fibrosis; Clinical and translational research in sarcoidosis

    Additional Information

  • Education +


    • Johns Hopkins University School of Medicine / MD (1994)


    • Columbia Presbyterian Medical Center / Internal Medicine (1997)


    • Johns Hopkins University School of Medicine / Pulmonary Diseases (2002)
    • Johns Hopkins Bayview Medical Center / Pulmonary Medicine (2003)


    • American Board of Internal Medicine / Critical Care Medicine (2003)
    • American Board of Internal Medicine / Internal Medicine (1997, 2007)
    • American Board of Internal Medicine / Pulmonary Disease (2002, 2012)
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Pontes TB, Chen ES, Gigek CO, Calcagno DQ, Wisnieski F, Leal MF, Demachki S, Assumpção PP, Artigiani R, Lourenço LG, Burbano RR, Arruda Cardoso Smith M. Reduced mRNA expression levels of MBD2 and MBD3 in gastric carcinogenesis. Tumour Biol. 2013 Dec 13. [Epub ahead of print] PMID: 24338710
    2. Chen ES, Hoch NC, Wang SC, Pellicioli A, Heierhorst J, Tsai MD. Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo. Mol Cell Proteomics. 2013 Dec 3. [Epub ahead of print] PMID: 24302356
    3. Mazzotti DR, Singulane CC, Ota VK, Rodrigues TP, Furuya TK, de Souza FJ, Cordeiro BG, de Oliveira Amaral CM, Chen ES, Jacomini A, de Arruda Cardoso Smith M, Borsatto-Galera B. Association of APOE, GCPII and MMP9 polymorphisms with common diseases and lipid levels in an older adult/elderly cohort. Gene. 2013 Nov 28. pii: S0378-1119(13)01566-7. doi: 10.1016/j.gene.2013.11.040. [Epub ahead of print] PMID: 24291031
    4. Wisnieski F, Calcagno DQ, Leal MF, Dos Santos LC, Gigek Cde O, Chen ES, Pontes TB, Assumpção PP, de Assumpção MB, Demachki S, Burbano RR, Smith Mde A. Reference genes for quantitative RT-PCR data in gastric tissues and cell lines. World J Gastroenterol. 2013 Nov 7;19(41):7121-8. doi: 10.3748/wjg.v19.i41.7121. PMID: 24222956
    5. Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF. Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med. 2013 Dec;19(12):1609-16. doi: 10.1038/nm.3385. Epub 2013 Nov 10. PMID: 24216752
    6. de Oliveira FF, Bertolucci PH, Chen ES, Smith MD. Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer's disease. J Neurol Sci. 2013 Oct 14. pii: S0022-510X(13)02961-4. doi: 10.1016/j.jns.2013.10.015. [Epub ahead of print] PMID: 24189208
    7. Tay Z, Koo SH, Nguyen TT, Tan TS, Chen ML, Chin CF, Lim KK, Ang WH, Bay BH, Lee EJ, Chen ES. P-glycoprotein and Vacuolar ATPase Synergistically Confer Anthracycline Resistance to Fission Yeast and Human Cells. Curr Med Chem. 2013;21(2):251-60. PMID: 24059229
    8. Silva PN, Furuya TK, Braga IL, Rasmussen LT, Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. J Alzheimers Dis. 2014;38(1):165-70. doi: 10.3233/JAD-130428. PMID: 23948933
    9. Rice KA, Chen ES, Metcalf Pate KA, Hutchinson EK, Adams RJ. Diagnosis of amyloidosis and differentiation from chronic, idiopathic enterocolitis in rhesus (Macaca mulatta) and pig-tailed (M. nemestrina) macaques. Comp Med. 2013 Jun;63(3):262-71. PMID: 23759529 [PubMed - in process]
    10. Hoch NC, Chen ES, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J. Molecular basis of the essential s phase function of the rad53 checkpoint kinase. Mol Cell Biol. 2013 Aug;33(16):3202-13. doi: 10.1128/MCB.00474-13. Epub 2013 Jun 10. PMID: 23754745

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