Skip Navigation
Find a Doctor
 
 
 
 

 

Photo of Dr. Cornelia Trimble

Cornelia Liu Trimble, M.D.

Associate Professor of Gynecology and Obstetrics

Female

Appointment Phone

443-997-0400

Main Location

Johns Hopkins Medicine - Green Spring Station

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Associate Professor of Gynecology and Obstetrics
  • Associate Professor of Oncology
  • Associate Professor of Pathology

Centers & Institutes

Departments

  • Gynecology and Obstetrics - Gynecologic Specialties
  • Oncology - Viral Oncology
  • Pathology

Locations

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 443-997-0400

10755 Falls Road
Pavilion I
Lutherville, MD 21093 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-6700

601 N. Caroline Street
Baltimore, MD 21287 map

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-7802

4940 Eastern Avenue
Baltimore, MD 21224 map

The Johns Hopkins Hospital

Appointment Phone: 443-997-0400

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

The Johns Hopkins Hospital

600 N. Wolfe Street
Halstead
Baltimore, MD 21287 map

Expertise

Cervical Cancer, Cervical Dysplasia, Gynecology and Obstetrics, Human Papillomavirus Infections

Research Interests

Cervical Cancer; HPV; Cancer Vaccines

    Additional Information

  • Education +

    Degrees

    • Vanderbilt University School of Medicine / MD; Medicine (1988)

    Residencies

    • New York Hospital / Pathology (1991)
    • Johns Hopkins University School of Medicine / Obstetrics and Gynecology (1997)

    Fellowships

    • Johns Hopkins University School of Medicine (1997)

    Certifications

    • American Board of Obstetrics and Gynecology / Obstetrics And Gynecology (2001, 2014)
    • American Board of Pathology / Anatomic Pathology (1993)
  • Research & Publications +

    Selected Publications

    Peng, S.; Tomson, T.T.; Trimble, C.; He, L.; Hung, C.F.; Wu, T.C. A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects. Gene Ther. 2006 Feb;13(3):257-265.
    Peng, S.; Trimble, C.; He, L.; Tsai, Y.C.; Lin, C.T.; Boyd, D.A.; Pardoll, D.; Hung, C.F.; Wu, T.C. Characterization of HLA-A2-restricted HPV-16 E7-specific CD8(+) T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice. Gene Ther. 2006 Jan;13(1):67-77.
    Rosenthal, D.L.; Geddes, S.; Trimble, C.L.; Carson, K.A.; Alli, P.M. The PapSpin: a reasonable alternative to other, more expensive liquid-based Papanicolaou tests. Cancer. 2006 Jun 25;108(3):137-143.
    Peng, S.; Trimble, C.; Wu, L.; Pardoll, D.; Roden, R.; Hung, C.F.; Wu, T.C. HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions. Clin Cancer Res. 2007 Apr 15;13(8):2479-2487.
    Partridge, E.E.; Abu-Rustum, N.; Campos, S.; Fahey, P.J.; Greer, B.E.; Lele, S.M.; Lieberman, R.W.; Lipscomb, G.H.; Morgan, M.; Nava, M.E.; Reynolds, R.K.; Singh, D.K.; Smith-McCune, K.; Teng, N.; Trimble, C.L.; Valea, F.; Wilczynski, S.; National Comprehensive Cancer, N. Cervical cancer screening. J Natl Compr Canc Netw. 2008 Jan;6(1):58-82.
    Peng, S.; Trimble, C.; Alvarez, R.D.; Huh, W.K.; Lin, Z.; Monie, A.; Hung, C.F.; Wu, T.C. Cluster intradermal DNA vaccination rapidly induces E7-specific CD8+ T-cell immune responses leading to therapeutic antitumor effects. Gene Ther. 2008 Aug;15(16):1156-1166.
    Trimble, C.L. Human papillomavirus vaccination should be offered to young males: Counterpoint. Cancer Epidemiol Biomarkers Prev. 2008 Apr;17(4):809.
    Tseng, C.W.; Hung, C.F.; Alvarez, R.D.; Trimble, C.; Huh, W.K.; Kim, D.; Chuang, C.M.; Lin, C.T.; Tsai, Y.C.; He, L.; Monie, A.; Wu, T.C. Pretreatment with cisplatin enhances E7-specific CD8+ T-Cell-mediated antitumor immunity induced by DNA vaccination. Clin Cancer Res. 2008 May 15;14(10):3185-3192.
    Tseng, C.W.; Monie, A.; Trimble, C.; Alvarez, R.D.; Huh, W.K.; Buchsbaum, D.J.; Straughn, J.M., Jr.; Wang, M.C.; Yagita, H.; Hung, C.F.; Wu, T.C. Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects. Vaccine. 2008 Aug 12;26(34):4314-4319.
    Tseng, C.W.; Trimble, C.; Zeng, Q.; Monie, A.; Alvarez, R.D.; Huh, W.K.; Hoory, T.; Wang, M.C.; Hung, C.F.; Wu, T.C. Low-dose radiation enhances therapeutic HPV DNA vaccination in tumor-bearing hosts. Cancer Immunol Immunother. 2008 Sep 25.
    Trimble, C.L.; Frazer, I.H. Development of therapeutic HPV vaccines. Lancet Oncol. 2009 Oct;10(10):975-980.
    Trimble, C.L.; Peng, S.; Kos, F.; Gravitt, P.; Viscidi, R.; Sugar, E.; Pardoll, D.; Wu, T.C. A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3. Clin Cancer Res. 2009 Jan 1;15(1):361-367.
    Trimble, C.L.; Peng, S.; Thoburn, C.; Kos, F.; Wu, T.C. Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3. Cancer Immunol Immunother. 2009 Dec 13.
    Tseng, C.W.; Trimble, C.; Zeng, Q.; Monie, A.; Alvarez, R.D.; Huh, W.K.; Hoory, T.; Wang, M.C.; Hung, C.F.; Wu, T.C. Low-dose radiation enhances therapeutic HPV DNA vaccination in tumor-bearing hosts. Cancer Immunol Immunother. 2009 May;58(5):737-748.
    Yen, H.R.; Harris, T.J.; Wada, S.; Grosso, J.F.; Getnet, D.; Goldberg, M.V.; Liang, K.L.; Bruno, T.C.; Pyle, K.J.; Chan, S.L.; Anders, R.A.; Trimble, C.L.; Adler, A.J.; Lin, T.Y.; Pardoll, D.M.; Huang, C.T.; Drake, C.G. Tc17 CD8 T cells: functional plasticity and subset diversity. J Immunol. 2009 Dec 1;183(11):7161-7168.
    Trimble, C.L.; Clark, R.A.; Thoburn, C.; Hanson, N.C.; Tassello, J.; Frosina, D.; Kos, F.; Teague, J.; Jiang, Y.; Barat, N.C.; Jungbluth, A.A. Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium. J Immunol. 2010 Dec 1;185(11):7107-7114.
    Trimble, C.L.; Peng, S.; Thoburn, C.; Kos, F.; Wu, T.C. Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3. Cancer Immunol Immunother. 2010 May;59(5):799-803.
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +

    Recent News Articles & Media Coverage

Is This You? Edit Profile
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.