Dr. Sponseller’s research is primarily clinical and focuses on genetic disorders, spinal deformity and trauma. His goal is to put clinical decision making on a scientific footing. His current projects include: outcomes of spinal deformity care in cerebral palsy, Loeys-Dietz syndrome and Marfan syndrome; understanding skeletal development and degeneration in a mouse model of Marfan syndrome; prevention of infection in spinal deformity; and improving pelvic fixation.
His research goals are to: (1) define the natural history of skeletal features of Marfan syndrome; (2) understand the basic science of the Marfan skeletal phenotype; (3) improve skeletal treatment in osteogenesis imperfecta; (4) advance the treatment of pediatric spinal deformity; and (5) improve the care of pediatric skeletal trauma.
Clinical Trial Keywords:
Growing Spinal Deformity
Jain A, Hassanzadeh H, Strike SA, Menga EN, Sponseller PD, Kebaish KM. Pelvic fixation in adult and pediatric spine surgery: Historical perspective, indications, and techniques. AAOS Exhibit Selection. J Bone Joint Surg Am. 2015;97(18):1521-1528.
Jain A, Brooks JT, Rao SS, Ain MC, Sponseller PD. Cervical fractures with associated spinal cord injury in children and adolescents: epidemiology, costs, and in-hospital mortality rates in 4418 patients. J Child Orthop. 2015;9(3):171-175.
Mesfin A, Nesterenko SO, Al-Hourani KG, Jain A, Sponseller PD. "Management of Hangman's fractures and a subaxial compression fracture in two children with osteogenesis imperfecta." J Surg Orthop Adv. 2013 Winter;22(4):326-9.
Menga EN, Jain A, Kebaish KM, Zimmerman SL, Sponseller PD. "Anatomic parameters: direct intralaminar screw repair of spondylolysis." Spine (Phila Pa 1976). 2014 Feb 1;39(3):E153-8. doi: 10.1097/BRS.0000000000000118.
Menga EN, Kebaish KM, Jain A, Carrino JA, Sponseller PD. "Clinical results and functional outcomes after direct intralaminar screw repair of spondylolysis." Spine (Phila Pa 1976). 2014 Jan 1;39(1):104-10. doi: 10.1097/BRS.0000000000000043.
Skaggs DL, Akbarnia BA, Flynn JM, Myung KS, Sponseller PD, Vitale MG. "A classification of growth friendly spine implants." Approved by the Chest Wall and Spine Deformity Study Group, the Growing Spine Study Group, Pediatric Orthopaedic Society of North America and the Scoliosis Research Society Growing Spine Study Committee. J Pediatr Orthop. 2013 Aug 29.
Sponseller PD, Jain A, Shah SA, Samdani A, Yaszay B, Newton PO, Thaxton LM, Bastrom TP, Marks MC. "Deep wound infections after spinal fusion in children with cerebral palsy: a prospective cohort study." Spine (Phila Pa 1976). 2013 Nov 1;38(23):2023-7. doi: 10.1097/BRS.0b013e3182a83e59.