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Photo of Dr. Theodore Bayless

Theodore M Bayless, M.D.

Director, Meyerhoff Digestive Disease- Inflammatory Bowel Disease Center (1985-88)


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Director, Meyerhoff Digestive Disease- Inflammatory Bowel Disease Center (1985-88)
  • Clinical Director, Gastroenterolgy Divisons (1988-1992)
  • Clinical Director Meyerhoff Inflammatory Bowel Disease Center (1988-2005)

Centers & Institutes



The Johns Hopkins Hospital

Appointment Phone: 410-933-7495

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-4916
Fax: 410-614-8799

The Johns Hopkins Hospital

600 N. Wolfe Street
Carnegie 446D1
Baltimore, MD 21287 map

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-583-2888

10755 Falls Road
Pavilion I
Lutherville, MD 21093 map

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-933-7495

2360 W. Joppa Road
Lutherville, MD 21093 map
Phone: 410-933-7495


Celiac Disease, Clinical Gastroenterology, Colitis, Crohn's Disease, Diarrhea, Digestive Diseases, Gastroenterology, Inflammatory Bowel Disease, Proctitis, Ulcerative Colitis

Research Interests

Crohn's Disease; Ulcerative Colitis; Inflammatory Bowel Disease; Genetics of Inflammatory Bowel Disease


Theodore M. Bayless, Professor of Medicine and Director Emeritus of the Meyerhoff Inflammatory Bowel Disease Center at Johns Hopkins is the first Sherlock Hibbs Professor in Inflammatory Bowel Disease.  A clinician, researcher and an educator, Dr. Bayless has been a member of faculty at Johns Hopkins since 1964 and has provided patient care for over 4000 patients with IBD.
Dr. Bayless received his undergraduate training at the University of Pennsylvania and at Bucknell University; his M.D. degree at Chicago Medical School; Internal Medicine training at the Cornell Division of Bellevue Hospital and Memorial Sloan-Kettering Cancer Center, New York; and Gastroenterology research training, with a focus on celiac disease, at the Johns Hopkins Hospital.
He was awarded the Franklin Institute Medal for his work showing that lactase activity was under genetic control and tested lactose hydrolyzed milk. Dr. Bayless co-authored 145 peer-reviewed research papers and was elected to the American Society for Clinical Investigation in 1975. In 1987, he received the first Distinguished Educator Award from the American Gastroenterological Association (AGA). In 2004, he received the Excellence in Teaching Award from the Johns Hopkins Alumni Association and he was again awarded by the AGA with a Distinguished Clinician Award.
As Director of the Meyerhoff Inflammatory Bowel Disease Center at Johns Hopkins he showed that within families with Crohn’s disease, the presentation of the illness was similar among multiple family members suggesting that there are separate types of Crohn’s disease. He and Dr. Steven R. Brant started the Meyerhoff IBD Family Study which showed that the strongest genetic linkage was in families with youthful onset and severe disease; and, most importantly, they collaborated on the first report of NOD2/CARD15 as a susceptibility gene in Crohn’s disease (Nature May, 2001). Patients with this gene change, as predicted by Dr. Bayless, show this type of youthful onset and complicated ileal disease. [Over 300 papers on NOD2/CARD15 have appeared since 2001]


Dr. Bayless served as Director of the AGA section on Immunology, Microbiology and Inflammatory Disorders and as National Chairman of the Crohn’s Colitis Foundation.  Dr. Bayless, an active clinician himself, has edited 13 books for practicing physicians and patients. He has a newly published book available on since November 2011 entitled "Advanced Therapy in Inflammatory Bowel Disease Vol III". more

    Additional Information

  • Education +


    • Chicago Medical School / MD (1957)


    • Cornell Division of Bellevue Hospital / Internal Medicine (1960)


    • Johns Hopkins University School of Medicine / Gastroenterology (1962)


    • American Board of Internal Medicine / Internal Medicine (1965)
  • Research & Publications +

    Clinical Trial Keywords: Biologics in inflammatory bowel disease

  • Academic Affiliations & Courses +
  • Activities & Honors +


    • American Society for Clinical Investigation
    • AOA Honor Medical lSociety
    • Distinguished Educator Award, American Gastroenterolgical Association, 1987
    • Bolton L. Corson Medal, Franklin Institute, Philadelphia, 1997
    • Distinguished Clinician Award, American Gastroenterolgical Association, 2004
    • Distinguished Educator Award, Johns Hopkins University Alumni Award, 2004
    • Chairman, National Scientific Committee Lotos Club, Crohn's and Colitis Foundation, New York City. One of the oldest literary clubs in US, 2007


    • Alpha Omega Alpha
    • American College of Physicians
      Eli and Edythe Broad Medical Foundation: Executive Committee
    • American Gastroenterology Association
  • Videos & Media +
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