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Richard Joseph O'Brien, MD

Professor of Neurology

See Research on Pubmed | See Research on Google Scholar



  • Professor of Neurology

Centers & Institutes

  • Cerebrospinal Fluid Disorders Clinic
  • Johns Hopkins Memory and Alzheimer's Disease Treatment Center


Alzheimer's Disease, Dementia, Hydrocephalus, Neurology

Research Interests

Dr O'Brien is an authority on the production of cerebrospinal fluid and the amyloid Aβ peptide, both key steps in the development of memory and gait disorders; Dr. O'Brien's laboratory investigates the molecular mechanisms that regulate the development and maintenance of excitatory synapses in the central nervous system


Dr O'Brien sees patients with memory disorders and with CSF disorders including normal pressure hydrocephalus (NPH) at The Johns Hopkins Bayview Medical Center.


  • English


American College of Physicians
American Academy of Neurology
Society for Neuroscience
American Neurological Association
American Heart Association Stroke Council

Additional Resources

Additional Resources +
  • Education +


    • Harvard Medical School (Boston MA) (1985)


    • Johns Hopkins University School of Medicine / Neurology (Baltimore MD) (1992)
    • Harvard Medical School (Boston MA) (1988)


    • Johns Hopkins University School of Medicine / Neurology (Baltimore MD) (1993)


    • American Board of Psychiatry & Neurology / Neurology (1994)
    • American Board of Internal Medicine / Internal Medicine (1988)
  • Research & Publications +
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Professional Activities

    Dr. Richard O''Brien is also the director of the Baltimore Longitudinal Study of Aging Autopsy Program, one of the nations premier studies of the cause of memory loss in the elderly.
  • Videos & Media +

    Recent News Articles & Media Coverage

    Heart Disease Could be Tied to Dementia for Older Women, Reuters (01/02/2014)

  • Events +
  • Contact & Locations +


    • Neurology - Center for CSF Disorders
    • Neurology - Hydrocephalus

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