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Photo of Dr. Constantine Lyketsos

Constantine George Lyketsos, MD

Elizabeth Plank Althouse Professor and Chair of Psychiatry, Johns Hopkins Bayview
Professor of Psychiatry and Behavioral Sciences
Male
Appointment Phone

410-550-6337

Main Location

Johns Hopkins Bayview Medical Center

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Titles

  • Elizabeth Plank Althouse Professor and Chair of Psychiatry, Johns Hopkins Bayview
  • Chairman, Department of Psychiatry, Johns Hopkins Bayview Medical Center
  • Vice Chairman, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins Hospital
  • Co-Director, Division of Geriatric Psychiatry and Neuropsychiatry
  • Director, Memory and Alzheimer''s Treatment Center
  • Professor of Psychiatry and Behavioral Sciences

Centers & Institutes

  • Alzheimer's Disease Research Center
  • Memory and Alzheimer's Disease Treatment Center

Expertise

Adult Psychiatry, Alzheimer's Disease, Dementia, Depression, Epidemiology, Geriatric Psychiatry, Memory Disorders, Mood Disorders, Neuropsychiatry, Stroke, Traumatic Brain Injury

Research Interests

Dementia; Alzheimer's disease; Late life depression; Epidemiology; Biomarkers; Brain imaging

Biography

An active clinician, teacher, and researcher, Dr. Lyketsos was the founding director of the Johns Hopkins Neuropsychiatry Service, which he led for over a decade. He developed one of the largest and most successful academic neuropsychiatry programs in the USA with special expertise in dementia and traumatic brain injury. Prior to assuming leadership position at Johns Hopkins Bayview, he was and co-director of the Johns Hopkins Division of Geriatric Psychiatry and Neuropsychiatry. He has held a joint faculty appointment at the Hopkins Bloomberg School of Public Health since 1994.

A world expert in the care and treatment of patients with Alzheimers and related dementias (AD), he has carried out pioneering work on the epidemiology and treatment of neuropsychiatric features of AD. His team is developing biomarkers to accelerate treatment development for AD and other forms of brain injury while designing and implementing innovative clinical trials. He leads efforts to ensure the provision of state of the art Dementia Care for people with dementia in the community. Dr. Lyketsos co-leads a Hopkins-wide effort to advance recovery of the wounded warrior and his family. He also serves on the NFL Players Association Mackey-White Mild Traumatic Brain Injury Committee for which he Chairs the Long-Term Outcomes subcommittee. In June 2010 he was Conference Chair of Traumatic Brain injury in Professional Football: An Evidence-Based Perspective sponsored by NFL.

As the Chair of the Academy of Psychosomatic Medicine Task Force on Subspecialization, Dr. Lyketsos was instrumental in the 2003 recognition by the American Board of Medical Specialties of the newest psychiatric subspecialty, Psychosomatic Medicine. This rapidly expanding subspecialty is focused on psychiatric aspects of complex medically ill, typically patients with chronic diseases, such as brain injury, where the psychiatric condition is affecting medical care and outcomes.

Languages

  • English
  • Greek

Memberships

American College of Psychiatrists
American College of Neuropsychophramacology
American Psychiatric Association
Academy of Psychosomatic Medicine
American Association for Geriatric Psychiatry

Clinical Trial Keywords

  • Alzheimer's Disease Collaborative Study

Additional Resources

Additional Resources +
  • Education +

    Training

    • Johns Hopkins Bloomberg School of Public Health (Baltimore MD ) (1994)
    • Washington University School of Medicine (St Louis MO ) (1988)

    Residencies

    • Johns Hopkins University School of Medicine / Psychiatry (Baltimore MD ) (1992)

    Fellowships

    • Johns Hopkins Bloomberg School of Public Health (Baltimore MD ) (1993)

    Certifications

    • American Board of Psychiatry & Neurology / Psychosomatic Medicine (2005)
    • American Board of Psychiatry & Neurology / Psychiatry (1994)
  • Research & Publications +

    Selected Publications



    1. Karlawish JHT, Bonnie R, Appelbaum PS, Lyketsos C, Karlan P, James BD, Sabatino C, Lawrence T, Knopman D, Kane RM. Identifying the barriers and challenges to voting by residents of nursing homes and assisted living settings: A study of the 2003 Philadelphia mayors race. J Aging and Soc Policy 2008; 20(1): 65-80

    2. Lee HB, Hening WA, Allen RP, Kalaydjian AE, Earley CJ, Eaton WW, Lyketsos CG. Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community. J Neuropsychiatry Clin Neurosci 2008;20(1):101-5

    3. Green AF, Rebok G, Lyketsos CG. Influence of social network characteristics on cognition and functional status with aging. Int J Geriatr Psychiatry 2008 May 1 [Epub ahead of print] [NIHMS79470; PMC2650477]

    4. Mielke MM, Bandaru VV, Haughey NJ, Rabins PV, Lyketsos CG, Carlson MC. Serum sphingomyelins and ceramides are early predictors of memory impairment. Neurobiol Aging 2008 May 1 [Epub ahead of print], [MSID 77994]

    5. Samus QM, Mayer L, Baker A, McNabney M, Brandt J, Onyike CU, Rabins PV, Lyketsos CG, Rosenblatt A. Characteristics and outcomes for assisted living residents with dementia: Comparing dementia-specific care units with non-dementia-specific care units. J Am Geriatr Soc 2008;56(7):1361-3 [NIHMSID 101959]

    6. Golden SH, Lazo M, Carnethon M, Bertoni AG, Schreiner PJ, Roux AV, Lee HB, Lyketsos C. Examining a bidirectional association between depressive symptoms and diabetes. JAMA. 2008;299(23):2751-9 [NIHMSID 2648841]

    7. Rosenberg PB, Mielke MM, Tschanz J, Rabins P, Green RC, Norton M, Corcoran C, Welsh-Bohmer KA, Breitner JCS, Munger R, Lyketsos CG. Effects of beta-blockers and lipid-lowering agents on rate of functional decline in Alzheimers Disease. Am J Geriatr Psychiatry 2008; 16(11):883-92 [NIHMSID 102061]

    8. McNabney MK, Samus QM, Lyketsos CG, Brandt J, Onyike CU, Baker A, Rosenblatt A. The spectrum of medical illness and medication use among residents of assisted living facilities in central Maryland. J Am Med Dir Assoc 2008 Oct;9(8):55864

    9. Kaplin A, Carroll KA, Cheng J, Allie R, Lyketsos CG, Calabresi P, Rosenberg PB. IL-6 release by LPS-stimulated peripheral blood mononuclear cells as a potential biomarker in Alzheimer''s disease. Int Psychogeriatr. 2008 Dec 1:1-2. [Epub ahead of print] [NIHMS: MS 102061]

    10. Steinberg M, Leoutsakos JM, Podewils LJ, Lyketsos CG. Evaluation of a home-based exercise program in the treatment of Alzheimer''s disease: The Maximizing Independence in Dementia (MIND) study. Int J Geriatr Psychiatry. 2008 Dec 16 [Epub ahead of print]

    11. Taragano FE, Allegri RF, Krupitzki H, Sarasola D, Serrano CM, Lo L, Lyketsos CG. Mild behavioral impairment and risk of dementia. J Clinical Psychiatry J Clin Psychiatry 2009 Apr;70(4):584-92. [NIHMS117195]

    12. Ceritoglu C, Oishi K, Li X, Chou MC, Younes L, Albert M, Lyketsos C, van Zijl PC, Miller MI, Mori S. Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging. Neuroimage 2009 May 3. [Epub ahead of print]

    13. Oishi K, Faria A, Jiang H, Li X, Akhter K, Zhang J, Hsu JT, Miller MI, van Zijl PC, Albert M, Lyketsos CG, Woods R, Toga AW, Pike GB, Rosa-Neto P, Evans A, Mazziotta J, Mori S. Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer''s disease participants. Neuroimage 2009 Jun;46(2):486-99.

    14. Zheng L, Mack WJ, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Stroup TS, Sultzer DL, Tariot PN, Vigen C, Schneider LS. Metabolic changes associated with second-generation antipsychotic use in Alzheimer''s disease patients: the CATIE-AD study. Am J Psychiatry 2009;166(5):583-90.

    15. Oishi K, Faria A, Jiang H, Li X, Akhter K, Zhang J, Hsu JT, Miller MI, van Zijl PC, Albert M, Lyketsos CG, Woods R, Toga AW, Pike GB, Rosa-Neto P, Evans A, Mazziotta J, Mori S.Atlas-based whole brain white matter analysis using Large Deformation Diffeomorphic Metric Mapping: Application to normal elderly and Alzheimer''s disease participants. Neuroimage 2009 Jan 19. [Epub ahead of print]

    16. Mielke MM, Kozauer NA, Chan KC, George M, Toroney J, Zerrate M, Bandeen-Roche K, Wang MC, Vanzijl P, Pekar JJ, Mori S, Lyketsos CG, Albert M. Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer''s disease. Neuroimage 2009 15;46(1):47-55. Epub 2009 Feb 5.

    17. Samus QM, Mayer L, Onyike CU, Brandt J, Baker A, McNabney M, Rabins PV, Lyketsos CG, and Rosenblatt A. Correlates of functional dependence among recently-admitted assisted living residents with and without dementia. J Am Med Dir Assoc 2009 Jun;10(5):323-9

    18. Norton MC, Piercy KW, Rabins PV, Green RC, Breitner JC, Ostbye T, Corcoran C, Welsh-Bohmer KA, Lyketsos CG*, Tschanz JT*. Caregiver-Recipient Closeness and Symptom Progression in Alzheimer Disease. The Cache County Dementia Progression Study. J Gerontol B Psychol Sci Soc Sci 2009 Jun 29. [Epub ahead of print] (*co-equal last authors)

    19. Rosenberg PB, Drye LT, Martin BK, Frangakis C, Mintzer JE, Weintraub, Porsteinsson AP, Schneider LS, Rabins PV, Munro CA, Meinert CL, Lyketsos, CG, for the DIADS-2 Research Group. Sertraline for the treatment of depression in Alzheimers disease. Am J Geriatric Psychiatry 2010;18:136-145 (NIHMS166961)

    20. Bicket MC, Samus QM, McNabney M, Onyike CU, Mayer LS, Brandt J, Rabins P, Lyketsos C, Rosenblatt A. The physical environment influences neuropsychiatric symptoms and other outcomes in assisted living residents. Int J Geriatr Psychiatry 2010 Jan 14 [Epub ahead of print]

    21. Weintraub D, Rosenberg PB, Drye LT, Martin BK, Frangakis C, Mintzer JE, Porsteinsson AP, Schneider LS, Rabins PV, Munro CA, Meinert CL, Lyketsos CG, for the DIADS-2 Research Group. Sertraline for the treatment of depression in Alzheimers disease: Week-24 outcomes. Am J Geriatr Psychiatry 2010 Feb 2. [Epub ahead of print] (NIHMSID #181111)

    22. Leoutsakos JM, Zandi PP, Bandeen-Roche K, Lyketsos CG. Searching for valid psychiatric phenotypes: discrete latent variable models. Int J Methods Psychiatr Res 2010 Feb 24. [Epub ahead of print]

    23. Qiu A, Oishi K, Miller MI, Lyketsos CG, Mori S, Albert M. Surface-based analysis on shape and fractional anisotropy of white matter tracts in Alzheimer''s disease. PLoS One 2010 Mar 22;5(3):e9811

    24. Munro CA, Jefferys J, Gower E, Munoz B, Lyketsos CG, Keay L, Turano KA, Bandeen-Roche K, West SK. Predictors of Lane Change Errors Among Elderly Drivers. J Am Geriatr Soc 2010 Mar;58(3):457-64

    25. Rao V, Rosenberg P, Miles QS, Patadia D, Treiber K, Bertrand M, Norton M, Steinberg M, Tschanz J, Lyketsos C. Neuropsychiatric symptoms in dementia patients with and without a history of traumatic brain injury. J Neuropsychiatry Clin Neurosci 2010 Spring;22(2):166-72

    26. Clarke DE, Ko JY, Lyketsos C, Rebok GW, Eaton WW. Apathy and cognitive and functional decline in community-dwelling older adults: Results from the Baltimore ECA longitudinal study. International Psychogeriatrics 2010 May; 18:1-11. [Epub ahead of print]

    27. Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, Dannals RF, Nandi A, Brasić JR, Ye W, Hilton J, Lyketsos C, Kung HF, Joshi AD, Skovronsky DM, Pontecorvo MJ. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (flobetapir F 18). Nucl Med 2010 Jun;51(6):913-20 (NIHMS 260423)

    28. de Medeiros K, Robert P, Gauthier S, Stella F, Politis A, Leoutsakos, J, Taragano F, Kremer J, Brugnolo A, Porsteinsson A, Geda Y, Brodaty H, Gazdag G, Cummings J, Lyketsos C. The neuropsychiatric inventory-clinician rating scale (NPI-C): Reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia. Int Psychogeriatr 2010; 22(6): 984-994

    29. Mohamed S, Rosenheck R, Lyketsos C, Schneider LS. Caregiver Burden in Alzheimer Disease: Cross-Sectional and Longitudinal Patient Correlates. Am J Geriatr Psychiatry 2010 Jun 7 [Epub ahead of print]

    30. McNabney M, Samus Q, Onyike C, Brandt J, Baker A, Lyketsos C, Rosenblatt A. Evaluation of care requirements among assisted living residents with specific chronic diseases. J Am Geriatr Soc 2010; 58; (Suppl. 1); 113-113

    31. Johnston DJ, Samus QM, Morrison A, Leoutsakos JS, Hicks K, Handel S, Rye R, Robbins B, Rabins PV, Lyketsos CG, Black BS. Identification of community-residing individuals with dementia and their unmet needs for care. Int J Geriatr Psychiatry 2010 Jul 23. [Epub ahead of print]

    32. Oh ES, Mielke MM, Rosenberg PB, Jain A, Fedarko N, Lyketsos CG, Mehta P. Comparison of conventional ELISA with electrochemiluminescence technology for detection of amyloid-beta (Aβ) in plasma. J Alzheimers Dis 2010 Jul 15. [Epub ahead of print]

    33. Drye L, Martin B, Frangakis C, Meinert C, Mintzer J, Munro C, Porsteinsson A, Rabins P, Rosenberg P, Schneider L, Weintraub D, Lyketsos C, for the DIADS-2 Research Group. Do treatment effects vary among differing baseline depression criteria in Depression in Alzheimer''s Disease Study - 2 (DIADS-2)? Int J Geriatr Psychiatry. 2010 Jul 28. [Epub ahead of print]

    34. Mougias AA, Politis A, Lyketsos CG, Mavreas VG. Quality of life in dementia patients in Athens, Greece: predictive factors and the role of caregiver-related factors. Int Psychogeriatr 2010 Aug; 12:1-9. [Epub ahead of print]

    35. Mielke MM, Haughey N, Bandaru VVR, Schech S, Carrick R, Carlson MC, Mori S, Miller MI, Ceritoglu C, Brown T, Albert M, Lyketsos CG. Plasma ceramides are altered in MCI and predict cognitive decline and hippocampal volume loss. Alzheimer''s & Dementia 2010 Sep;6(5):378-85

    36. Fillit H, Hofbauer RK, Setyawan J, Tourkodimitris S, Fridman M, Pejović V, Miller ML, Erder MH, Lyketsos C. Memantine Discontinuation and the Health Status of Nursing Home Residents With Alzheimer''s Disease. J Am Med Directors Association, October 2010, 11 (8): pp. 606-614

    37. Rosenberg PB, Mielke MM, Appleby B, Oh E, Leoutsakos J-M, Lyketsos CG. Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction. Int J Geriatric Psychiatry 2010 Sep 15 [Epub ahead of print]

    38. Lyketsos CG, Weiller E, Katona C, Gorwood P. Are old-old patients with major depression more likely to relapse than young-old patients during continuation treatment with escitalopram? BMC Geriatrics 2011 Jan 14;11:2

    39. Marquardt G, Johnston D, Black B, Morrison A, Rosenblatt A, Lyketsos, C, Samus QM. Association of the spatial layout of the home and ADL abilities among older adults with dementia. Am J Alzheimers Dis Other Demen 2011 Feb;26(1):51-7

    40. Treiber K, Carlson M, Corcoran C, Norton MC, Piercy K, MS Deberard, Stein D, Foley B, Welsh-Bohmer KA, Breitner JCS, Lyketsos CG*, Tschanz JT*. Cognitive Stimulation and Cognitive and Functional Decline in Alzheimer''s Disease: The Cache County Dementia Progression Study. J Gerontol B Psychol Sci Soc Sci 2011 Mar 25. [Epub ahead of print]

    41. Leoutsakos JS, Muthen BO, Breitner JCS, Lyketsos CG. Effects of NSAID treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: Findings from the randomized controlled ADAPT trial. Int J Geriatr Psychiatry 2011 May 10. doi: 10.1002/gps.2723. [Epub ahead of print]

    42. Vigen CL, Mack WJ, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS. Cognitive Effects of Atypical Antipsychotic Medications in Patients With Alzheimer''s Disease: Outcomes From CATIE-AD. Am J Psychiatry 2011 May 15. [Epub ahead of print]

    43. Marquardt G, Johnston D, Black B, Morrison A, Rosenblatt A, Lyketsos C, Samus QM (2011). A descriptive study of Home Modifications for People with Dementia and barriers to implementation. Journal of Housing for the Elderly 2011; 25(3), 258-273

    44. Mielke MM, Leoutsakos JM, Tschanz JT, Green RC, Tripodis Y, Corcoran CD, Norton MC, Lyketsos CG. Interaction Between Vascular Factors and the APOE E4 Allele in Predicting Rate of Progression in Alzheimer''s Disease. J Alzheimers Dis. 2011 May 18. [Epub ahead of print]

    45. Tschanz JT, Corcoran CD, Schwartz S, Treiber K, Green RC, Norton MC, Mielke MM, Piercy K, Steinberg M, Rabins PV, Leoutsakos JM, Welsh-Bohmer KA, Breitner JCS, Lyketsos CG. Progression of cognitive, functional and neuropsychiatric symptom domains in a population cohort with Alzheimer''s dementia. Am J Geriatr Psychiatry. 2011 Jun;19(6):532-542

    46. Gracia-Garcia P, Rao V, Haughey NJ, Bandaru VVR, Smith G, Rosenberg PB, Lobo A, Lyketsos CG, Mielke MM. Plasma ceramides are elevated in depression. J Neuropsychiatry Clin Neurosci 2011;23(2):215-8

    47. Breitner JCS, Baker LD, Montine TG , Meinert CL, Lyketsos CG, Ashe KH, Brandt J, Craft S, Evans DE, Green RC, Ismail MS, Martin BK, Mullan MJ, Sabbagh M, Tariot P, for the ADAPT Research Group. Extended results of the Alzheimer disease anti-inflammatory prevention trial (ADAPT). Alzheimers Dement 2011 Jul;7(4):402-11

    48. Shinohara RT, Frangakis CE, Lyketsos CG. A broad symmetry criterion for nonparametric validity of parametrically based tests in randomized trials. Biometrics 2011 Jul 15. doi: 10.1111/j.1541-0420.2011.01642.x. [Epub ahead of print]

    49. Fields C, Vaidya VJ, Drye L, Lyketsos CG. Celecoxib or naproxen treatment does not benefit depressive symptoms in persons aged 70 and over: findings from a randomized controlled trial. Am J Geriatr Psychiatry 2011 Jul 19. [Epub ahead of print]

    50. Mielke MM, Haughey NJ, Bandaru VVR, Weinberg DD, Darby E, Zaidi N, Pavlik V, Doody RS, Lyketsos, CG. Plasma sphingomeylins are associated with cognitive progression in Alzheimer''s Disease. J Alzheimers Dis 2011 Aug 12. [Epub ahead of print]

    51. Oishi K, Mielke MM, Albert M, Lyketsos CG, Mori S. The Fornix Sign: A Potential Sign for Alzheimer''s Disease Based on Diffusion Tensor Imaging. J Neuroimaging 2011 Aug 17. doi: 10.1111/j.1552-6569.2011.00633.x. [Epub ahead of print]

    52. Oishi K, Akhter K, Mielke M, Ceritoglu C, Zhang J, Jiang H, Li X, Younes L, Miller MI, van Zijl P, Albert M, Lyketsos C, Mori S. Multi-modal MRI analysis with disease-specific spatial filtering: initial testing to predict mild cognitive impairment patients who convert to Alzheimers disease. Front Neurol 2011;2:54. Epub 2011 Aug 24 [Epub ahead of print]

    53. Duff, K, Lyketsos CG, Beglinger LJ, Chelune G, Moser DJ, Arndt S, Schultz SK. Practice effects predict cognitive outcome in amnestic mild cognitive impairment Am J Geriatr Psychiatry 2011; 19(11), 932939.

    54. Mohamed S, Rosenheck R, Lyketsos CG, Kaczynski R, Sultzer DL, Schneider LS. Effect of second-generation antipsychotics on caregiver burden in Alzheimer''s disease. J Clin Psychiatry 2011 Sep 6. [Epub ahead of print]

    55. Black BS, Johnston D, Morrison A, Rabins PV, Lyketsos CG, Samus QM. Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures. Qual Life Res 2011 Oct 26 [Epub ahead of print]

    56. Drye LT, Ismail Z, Porsteinsson AP, Rosenberg PB, Weintraub D, Marano C, Pelton G, Frangakis C, Rabins PV, Munro CA, Meinert CL, Devanand DP, Yesavage G, Mintzer JE, Schneider LS, Pollock BG, Lyketsos CG, for the CitAD Research Group. Citalopram for agitation in Alzheimers disease (CitAD): design and methods. Alzheimer''s & Dementia, doi:10.1016/j.jalz.2011.01.007 [Epub ahead of print]

    57. Mielke MM, Leoutsakos J-M, Corcoran CD, Green RC, Norton MC, Welsh-Bohmer KA, Tschanz JT, Lyketsos CG. Effects of Food and Drug Administration approved medications for Alzheimer''s disease on clinical progression. Alzheimers Dement. 2012 Feb 1. [Epub ahead of print]

    58. Peters ME, Vaidya V, Drye LT, Rosenberg PB, Martin BK, Porsteinsson AP, Frangakis CE, Mintzer J, Weintraub D, Schneider LS, Rabins PV, Munro CA, Meinert CL, Lyketsos CG, Avramopoulos D; DIADS-2 Research Group. Sertraline for the treatment of depression in Alzheimer disease: genetic influences. J Geriatr Psychiatry Neurol. 2011 Dec;24(4):222-8. doi: 10.1177/0891988711422527.

    59. Lee CT, Leoutsakos JM, Lyketsos CG, Steffens DC, Breitner JC, Norton MC. Latent class-derived subgroups of depressive symptoms in a community sample of older adults: the Cache County Study. Int J Geriatr Psychiatry. 2011 Dec 2. doi: 10.1002/gps.2824. [Epub ahead of print]

    60. Rosenberg PB, Mielke MME, Han D, Leoutsakos JS, Lyketsos CG, Rabins PV, Zandi PP, Breitner JCS, Norton MC, Welsh-Bohmer KA, Zuckerman IH, Rattinger GB, Green RC, Corcoran D, Tschanz JT. The association of psychotropic medication use with the cognitive, functional and neuropsychiatric trajectory of Alzheimers disease. Int J Geriatr Psychiatry. 2012 Feb 29. doi: 10.1002/gps.3769. [Epub ahead of print]

    61. Mielke MM, Okonkwo OC, Oishi K, Mori S, Tighe S, Miller MI, Ceritoglu C, Brown T, Albert M, Lyketsos CG. Fornix integrity and hippocampal volume predict memory decline and progression to AD. Alzheimers Dement 2012 Mar;8(2):105-13

    62. Buckley T, Fauth EB, Morrison A, Tschanz J, Rabins PV, Piercy KW, Norton M, Lyketsos C. Predictors of Quality of Life Ratings for Persons with Dementia Simultaneously Reported by Patients and their Caregivers: The Cache County (Utah) Study. Int Psychogeriatr 2012 Mar 14:1-9. [Epub ahead of print]

    63. Rosenberg PB, Mielke MM, Appleby BS, Oh ES, Geda YE, Lyketsos CG. The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimers Disease. Am J Geriatr Psychiatry 2012 Apr 27. [Epub ahead of print]

    64. Parker DC, Mielke MM, Yu Q, Rosenberg PB, Jain A, Lyketsos CG, Fedarko NS, Oh ES. Plasma neopterin level as a marker of peripheral cellular immune activation in amnestic mild cognitive impairment (aMCI) and Alzheimers disease. Int J Geriatr Psychiatry 2012 Apr 27. doi: 10.1002/gps.3802. [Epub ahead of print]

    65. Fauth E, Hess K, Piercy K, Norton M, Corcoran C, Rabins P, Lyketsos C, & Tschanz J. Caregivers relationship closeness with the person with dementia predicts both positive and negative outcomes for caregivers physical health and psychological well-being. Aging Ment Health 2012 May 1. [Epub ahead of print]

    66. Peters ME, Rosenberg PB, Steinberg M, Tschanz JT, Norton MC, Welsh-Bohmer KA, Hayden KM, Breitner JC, Lyketsos CG; the Cache County Investigators. Prevalence of Neuropsychiatric Symptoms in CIND and Its Subtypes: The Cache County Study. Am J Geriatr Psychiatry 2012 May;20(5):416-424.

    67. Rabins PV, Schwartz S, Black BS, Corcoran C, Fauth Elizabeth, Mielke M, Christensen J, Lyketsos C*, Tschanz *J. Predictors of progression to severe Alzheimer Disease in an incidence sample. Alzheimer''s and Dementia, in press. (*co-equal senior authors)

    68. Rosenberg PB, Wong DF, Edell S, Ross JS, Joshi AD, Braić JR, Zhou Y, Raymont V, Kumar A, Ravert HT, Dannals RF, Pontecorvo MJ, Skovronsky DM, Lyketsos CG. Cognition and amyloid load in Alzheimers imaged with florbetapir F 18 (AV-45) PET. Am J Geriatr Psychiatry, in press

    69. Tschanz JT, Piercy K, Corcoran CD, Fauth E, Norton MC, Rabins PV, Tschanz BT, Deberard MS, Snyder C, Smith C, Lee L, Lyketsos CG. Caregiver coping strategies predict cognitive and functional decline in dementia: The Cache County Dementia Progression Study. Am J of Geriatric Psychiatry, in press

    70. Munro CA, Longmire CF, Drye LT, Martin BK, Frangakis CE, Meinert CL, MintzerJE, Porsteinsson AP, Rabins PV, Rosenberg PB, Schneider LZ, Weintraub D, Lyketsos CG, for the DIADS-2 Research Group. Cognitive outcomes after sertraline treatment in patients with depression of Alzheimers disease (in press). American Journal of Geriatric Psychiatry.

    .


  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    William Proxmire Award for the Fight Against Alzheimer''s

    Distinguished Scientist Award, American Association for Geriatric Psychiatry

    Professional Activities

    Dr. Lyketsos is a Distinguished Fellow of the American Psychiatric Association, Fellow of the American College of Neuropsychopharmacology, and elected member of the the American College of Psychiatrists, he has written over 350 peer-reviewed journal articles, chapters, or commentaries. He is Editor of International Review of Psychiatry, Associate Editor of the American Journal of Psychiatry, and Deputy Editor of International Psychogeriatrics. He is co-author of Practical Dementia Care, lead Editor of the highly acclaimed Psychiatric Aspects of Neurologic Diseases: Practical Approaches to Patient Care, and co-author of Systematic Psychiatric Evaluation.

    Dr. Lyketsos has been cited as one of Americas Top Doctors for the past decade.

  • Videos & Media +
  • Events +
  • Contact & Locations +

    Locations

    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Alpha Commons
    4th Floor
    Baltimore, MD 21224
    Phone: 410-550-6337
    Appointment Phone: 410-550-6337
    Location Map

    Department/Division

    • Psychiatry and Behavioral Sciences - Geriatric Psychiatry and Neuropsychiatry
    • Psychiatry and Behavioral Sciences - JHBMC

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