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Srinivasa N Raja, MD

Director, Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine
Professor of Anesthesiology and Critical Care Medicine
Male
Appointment Phone

410-955-1822

Main Location

The Johns Hopkins Hospital

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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine
  • Director of Pain Research, Department of Anesthesiology and Critical Care Medicine
  • Professor of Anesthesiology and Critical Care Medicine
  • Professor of Neurology

Centers & Institutes

  • Blaustein Pain Treatment Center

Expertise

Anesthesiology, Neuralgia, Neuropathies, Pain Management

Research Interests

Peripheral and central mechanisms of neuropathic pain

Biography

Dr. Srinivasa N. Raja is a professor of anesthesiology and critical care medicine and neurology at the Johns Hopkins University School of Medicine. Dr. Raja serves as director of pain research and director of the Division of Pain Medicine in the Department of Anesthesiology and Critical Care Medicine.

Dr. Raja’s clinical interests include management of chronic pain states, such as complex regional pain syndromes, sympathetically maintained pain, post-therapeutic neuralgia and post-amputation pain.

He received his early medical training in India, his residency training in anesthesiology at the University of Washington and post-doctoral training at the University of Virginia School of Medicine. He received diplomate certification from the American Board of Anesthesiology in 1982. He added qualifications in pain management in 1993 and was recertified in 2002.

Dr. Raja served as editor of Anesthesiology from 1998 to 2006. He established the “Classic Papers Revisited” section in 2000 and served as its section editor. He is presently a section editor (Clinical:Science, Epidemiology and Clinical Notes) for the journal Pain. He is vice chair of the International Association for the Study of Pain (IASP), a neuropathic pain special interest group.

Dr. Raja and his collaborators have published more than 170 articles in peer-reviewed journals such as Anesthesia and Analgesia, Anesthesiology, Brain, Journal of Neurophysiology, The Journal of Neuroscience, Nature, Neurology, Pain and Science. He is an editor of four books and has written numerous book chapters. He has been invited to lecture both nationally and internationally and has been invited to several universities as a visiting professor.

Dr. Raja’s awards include the 14th annual Benjamin G. Covino lecture at Harvard University in 2008, the Wilbert E. Fordyce Clinical Investigator Award from the American Pain Society in 2008 and the John J. Bonic Award from the American Society of Regional Anesthesia and Pain Medicine in 2010.

Languages

  • English
  • Tamil
  • Hindi

Memberships

American Academy of Pain Medicine

American Pain Society

American Society of Anesthesiologists

Association of University Anesthesiologists

International Association for the Study of Pain

Society for Neuroscience

Amputee Coalition of America

Reflex Sympathetic Dystrophy Association of America

Clinical Trial Keywords

  • CRPS (reflex sympathetic dystrophy, causalgia)
  • Postamputation pain
  • Postherpetic neuralgia

Additional Resources

Additional Resources +
  • Education +

    Training

    • Patna Medical College Patna University (Patna Bihar State ) (1974)

    Certifications

    • American Board of Anesthesiology / Anesthesiology (1982)
  • Research & Publications +

    Research Summary

    Dr. Raja’s research efforts are aimed at understanding the peripheral and central mechanisms of neuropathic pain and in determining the role of opioid and adrenergic receptor mechanisms in mediating or maintaining chronic neuropathic pain states.

    His lab is also involved in studies to determine the mechanisms of actions of spinal cord stimulation for chronic pain. He has conducted controlled clinical trials to develop better evidence-based practices for the pharmacological treatment of neuropathic pain.

    Selected Publications

    1. Wu CL, Raja SN. “An update on the treatment of postherpetic neuralgia.” J Pain. 2008 Jan;9(1 Suppl 1):S19-30. doi: 10.1016/j.jpain.2007.10.006. Review.
    2. Guan Y, Johanek LM, Hartke TV, Shim B, Tao YX, Ringkamp M, Meyer RA, Raja SN. “Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury.” Pain. 2008 Aug 31;138(2):318-29. doi: 10.1016/j.pain.2008.01.004. Epub 2008 Feb 13.
    3. Kudel I, Edwards RR, Kozachik S, Block BM, Agarwal S, Heinberg LJ, Haythornthwaite J, Raja SN. “Predictors and consequences of multiple persistent postmastectomy pains.” J Pain Symptom Manage. 2007 Dec;34(6):619-27. Epub 2007 Jul 16.
    4. Guan Y, Borzan J, Meyer RA, Raja SN. “Windup in dorsal horn neurons is modulated by endogenous spinal mu-opioid mechanisms.” J Neurosci. 2006 Apr 19;26(16):4298-307.
    5. Lin EE, Horasek S, Agarwal S, Wu CL, Raja SN. “Local administration of norepinephrine in the stump evokes dose-dependent pain in amputees.” Clin J Pain. 2006 Jun;22(5):482-6.
    6. Chu YC, Guan Y, Skinner J, Raja SN, Johns RA, Tao YX. “Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain.” Pain. 2005 Dec 15;119(1-3):113-23. Epub 2005 Nov 16.

    Lab

    Dr. Srinivasa N. Raja's Lab

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    John J. Bonica Award, American Society of Regional Anesthesia and Pain Medicine, 2010

    Wilbert E. Fordyce Clinical Investigator Award, American Pain Society, 2008

    John J. Bonica Lecturer, University of Washington, 2008

    Benjamin Covino Lectureship, Harvard University, 2008

    Selected for Marquis Who’s Who in Medicine and Healthcare 4th ed., 2002

    Citation Poster Award, American Pain Society, 2000

    Outstanding Teacher Award, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 1982 - 1983

    National Research Service Award, National Institute of General Medical Sciences at the University of Virginia, 1979 - 1981

    Merit Scholarship, Patna University, 1972 - 1973

    Professional Activities

    Executive Committee, Neuropathic Pain Special Interest Group, IASP

    Section Editor, Pain

    Clinical Trials Editor, MD Consult Pain Medicine, 2002 - present

    Chair, Scientific Advisory Committee for the 15th World Congress on Pain, 2014

    Executive Committee, International Association for the Study of Pain (IASP), 2014

    Member, Scientific Program Committee, World Congress on Pain 2010

    Director-at-Large, American Pain Society, 2006 - 2009

    Co-Chair, Scientific Advisory Board, Reflex Sympathetic Dystrophy Syndrome Association (RSDSA), 2002

    Section Editor, Classic Papers Revisited, Anesthesiology, 1999 - 2006

    Editor, Anesthesiology, 1998 - 2006

    Chairman, Professional Development Courses, Annual Meeting of the American Pain Society, 1995

    Co-Director, Pain Management Services, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 1991 - 1993

    Chairman, Clinical Research Committee, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 1990 - 1992

    President, Neurosciences Division of the Association of Scientists of Indian Origin in America, 1986

  • Videos & Media +

    Videos

    Neuropathic Pain: Bridging Bedside to Bench, Part I

    Dr. Raja discusses neuropathic pain caused by injury or disease.

    Neuropathic Pain: Bridging Bedside to Bench, Part II

    Dr. Raja discusses neuropathic pain caused by injury or disease.

    Neuropathic Pain: Bridging Bedside to Bench, Part III

    Dr. Raja discusses neuropathic pain caused by injury or disease.

  • Events +
  • Contact & Locations +

    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-955-1822
    Appointment Phone: 410-955-1822
    Location Map
    Johns Hopkins Outpatient Center
    601 N. Caroline Street
    Baltimore, MD 21287
    Phone: 410-955-7246
    Appointment Phone: 410-955-7246
    Location Map

    Department/Division

    • Anesthesiology and Critical Care Medicine - Pain Medicine

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