Skip Navigation
Find a Doctor
 
 
 
 

 

Photo of Dr. Gary Gerstenblith

Gary Gerstenblith, J.D., M.D.

Director of clinical trials, Division of Cardiology
Professor of Medicine

Male

Appointment Phone

410-955-5000

Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Director of clinical trials, Division of Cardiology
  • Professor of Medicine
  • Joint Appointment in Radiology and Radiological Science

Centers & Institutes

Departments

Locations

The Johns Hopkins Hospital

Appointment Phone: 410-955-5000

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-6835

Expertise

Cardiology , Cardiovascular Disease, Coronary Artery Disease, Coronary Care Unit, Heart Disease

Biography

Dr. Gary Gerstenblith is professor of medicine and director of clinical trials in the Johns Hopkins Medicine Division of Cardiology. He also serves as attending physician in r the Cardiology care Unit.

Dr. Gerstenblith earned his undergraduate degree from New York University and his medical degree from the University of Pennsylvania School of Medicine. After working at the National Institute on Aging and the National Institutes of Health (NIH) and completing a fellowship at Jackson Memorial Hospital in Miami, Dr. Gerstenblith joined the faculty of the Johns Hopkins University School of Medicine.

Dr. Gerstenblith conducts clinical trials in patients with cardiovascular disease. His research interests include the impact of cardiovascular aging on cardiac structure and function, and the use of stem cells to repair damaged cardiac muscle. He has published nearly 250 articles and book chapters and has been a referee for numerous journals including Circulation, The New England Journal of Medicine and The Journal of the American College of Cardiology.

...read more

Featured Video

Stem Cell Implants to Repair Damaged Hearts, Part I

More Videos

    Additional Information

  • Education +

    Degrees

    • Hospital of the University of Pennsylvania / M.D.; Medicine (1971)

    Residencies

    • Hospital of the University of Pennsylvania / Medicine (1973)

    Fellowships

    • University of Miami School of Medicine / Cardiology (1977)

    Certifications

    • American Board of Internal Medicine / Cardiovascular Disease (1977)
    • American Board of Internal Medicine / Internal Medicine (1974)
  • Research & Publications +

    Technology Expertise: Cardiovascular Aging, Coronary Artery Disease

    Clinical Trials:

    Impact of xanthine oxidase inhibition on coronary endothelial function


    Clinical Trial Keywords: coronary endothelial function, coronary artery disease, Xanthine oxidase inhibition

    Selected Publications

    Hirsch GA, Bottonley P, Gerstenblith G, Weiss RG. Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts. JACC 59:802-8, 2012.

    Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marban L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marban E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CACUCEUS): a prospective, randomised phase 1 trial. Lancet 379:895-904, 2012.

    Karantalis V, DiFede DL, Gerstenblith G, Pham S, Symes J, Zambrano JP, Fishman J, Pattany P, McNiece I, Conte J, Schulman S, Wu K, Shah A, Breton E, Davis-Sproul J, Schwarz R, Feigenbaum G, Mushtaq M, Suncion VY, Lardo AC, Borrello I, Mendizabal A, Karas TZ, Byrnes J, Lowery M, Heldman AW, Hare JM. Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing coronary artery bypass grafting: The Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) trial. Circ Res 114:1302-10, 2014.

    Bottomley PA, Panjrath GS, Lai S, Hirsch GA, Wu K, Najjar SS, Steinberg A, Gerstenblith G, Weiss RG. Metabolic rates of ATP transfer through creatine kinase (CK flux) predict clinical heart failure events and death. Sci Transl Med 5:215re3, 2013.

    Hays AG, Stuber M, Hirsch GA, Yu J, Schar M, Weiss RG, Gerstenblith G, Kelle S. Non-invasive detection of coronary endothelial response to sequential handgrip exercise in coronary artery disease patients and healthy adults. PLos ONE 8(3):e58047, 2013.

    Assayag M, Saada A. Gerstenblith G, Canaana H, Shlomai R, Horowitz M. Mitochondrial performance in heat acclimation—a lesson from ischemia/reperfusion and calcium overload insults in the heart. Am J Physiol 303:R870-81, 2012.

    Hare JM, Fishman JE, Gerstenblith G, DiFede Velazquez DL, Zambrano JP, Suncion VY, Tracy M, Ghersin E, Johnston PV, Brinker JA, Breton E, Davis-Sproul J. Schulman IH, Byrnes J, Mendizabal AM, Lowery MH, Rouy D, Altman P, Wong Po Foo C, Ruiz P, Amador A, Da Silva J, McNiece IK, Heldman AW. Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial. JAMA 308:2369-79, 2012.

    Barth AS, Zhang Y, Li T, Smith RR, Chimenti I, Terrovitis I, Davis DR, Kizana E, Ho AS, O’Rourke B, Wolff AC, Gerstenblith G, Marban E. Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic agent trastuzumab. Stem Cells Transl Med 1:289-97, 2012.

    Hirsch GA, Bottonley P, Gerstenblith G, Weiss RG. Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts. JACC 59:802-8, 2012.

    Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marban L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marban E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CACUCEUS): a prospective, randomised phase 1 trial. Lancet 379:895-904, 2012.

    Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi S, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG. Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. J Clin Invest 122:291-302, 2012.

    Wu KC, Gerstenblith G, Guallar E, Marine JE, Dalal D, Cheng A, Marban E, Lima JA, Tomaselli GF, Weiss RG. Combined cardiac magnetic resonance imaging and C-reactive protein levels identify a cohort at low risk for defibrillator firings and death. Circ Cardiovasc Imaging 5:178-86, 2012.

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    • Alpha Omega Alpha, University of Pennsylvania School of Medicine
    • Fellow, American College of Chest Physicians
    • Fellow, American College of Legal Medicine
    • Fellow (FACC) , American College of Cardiology
    • Phi Beta Kappa , New York University
    • Who’s Who in Medicine and Healthcare , Marquis Who’s Who

    Memberships

    • American College of Physicians
    • American Federation for Clinical Research
    • American Heart Association
    • Association of University Cardiologists
    • Society of Magnetic Resonance in Medicine
    • The Johns Hopkins Medical and Surgical Association
  • Videos & Media +

    Videos

    Stem Cell Implants to Repair Damaged Hearts, Part II

Is This You? Edit Profile
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.