Structure/function analysis of chloride channels expressed in epithelial tissues and retinal neurons; Determining the biological role of the CFTR protein by identifying mutations in patients with CF characterization of CFTR transcripts and protein from patients of various genotypes and analysis of chloride conduction properties of mutated CFTR expressed in various cell types; Identifying genetic variants that contribute to chronic lung disease by linkage and candidate gene approaches; Determining CFTR genotype in phenotypes that overlap with cystic fibrosis (atypical CF, chronic sinusitis, male infertility and obstructive lung diseases); Cystic fibrosis
Dr. Gary Cutting is a professor of pediatrics and medicine and the Aetna U.S. Healthcare Professor of Medical Genetics in the McKusick-Nathans Institute of Genetic Medicine. He holds bachelor’s and medical degrees from the University of Connecticut.
Dr. Cutting completed a pediatric residency and fellowship in clinical genetics at Johns Hopkins University School of Medicine before joining the faculty in 1989.
Dr. Cutting’s additional appointments include director of postdoctoral training programs in medical genetics, director of the DNA Diagnostic Laboratory for the Johns Hopkins University School of Medicine, and director of the Genetics Translational Technology Core for the Institute for Clinical and Translational Research. He is also the director of the CFTR2 project, a worldwide collection of genotype and phenotype data on over 40,000 patients with cystic fibrosis.
Dr. Cutting is a member of the American Society of Human Genetics, the Association for Research in Vision and Ophthalmology and the American College of Medical Genetics. He is also a committee member of the U.S. Cystic Fibrosis Foundation and serves on the editorial board of Human Mutation, Genetic Testing and Current Molecular Medicine, as well as the Journal of Cystic Fibrosis.
His work has been recognized by The Paul di Sant’Agnese, and he has received the Distinguished Scientific Achievement Award from the CF Foundation, the Merck Clinician Scientist Award and the Linda Ives Award in Basic Sciences Research in Pediatrics.