Dr. Rowe’s research focuses on chronic fatigue syndrome (CFS). He is interested in the association between circulatory abnormalities and fatigue in cancer survivors, fatiguing illnesses in Gulf War veterans, and fatigue in athletes.
He was the first to describe the relationship between CFS and treatable orthostatic intolerance syndromes, as well as the association between Ehlers-Danlos syndrome and CFS. This research has been funded by the National Institutes of Health, the U.S. Department of Defense, the CFIDS Association of America, and several smaller foundations, as well as by private philanthropy.
Rowe PC, Marden CL, Flaherty MA, Jasion SE, Cranston EM, Johns AS, Fan J, Fontaine KR, Violand RL. "Impaired range of motion of limbs and spine in chronic fatigue syndrome." J Pediatr. 2014 Aug;165(2):360-6. doi: 10.1016/j.jpeds.2014.04.051. Epub 2014 Jun 11.
Sulheim D, Fagermoen E, Winger A, Andersen AM, Godang K, Müller F, Rowe PC, Saul JP, Skovlund E, Øie MG, Wyller VB. "Disease mechanisms and clonidine treatment in adolescent chronic fatigue syndrome: a combined cross-sectional and randomized clinical trial." JAMA Pediatr. 2014 Apr;168(4):351-60. doi: 10.1001/jamapediatrics.2013.4647.
Ross AJ, Medow MS, Rowe PC, Stewart JM. "What is brain fog? An evaluation of the symptom in postural tachycardia syndrome." Clin Auton Res. 2013 Dec;23(6):305-11. doi: 10.1007/s10286-013-0212-z. Epub 2013 Sep 3.
Rowe PC, Fontaine KR, Violand RL. "Neuromuscular strain as a contributor to cognitive and other symptoms in chronic fatigue syndrome: hypothesis and conceptual model." Front Physiol. 2013 May 16;4:115. doi: 10.3389/fphys.2013.00115. eCollection 2013.
Fortunato JE, Shaltout HA, Larkin MM, Rowe PC, Diz DI, Koch KL. "Fludrocortisone improves nausea in children with orthostatic intolerance (OI)." Clin Auton Res. 2011 Dec;21(6):419-23. doi: 10.1007/s10286-011-0130-x. Epub 2011 Jul 28."
Klassen TP, Feldman ME, Watters LK, Sutcliffe T, Rowe PC. Nebulized budesonide for children with mild-to-moderate croup. N Engl J Med 1994;331:285-9.
Rowe PC, ed. The Harriet Lane Handbook, 11th ed. Chicago: Year Book Medical Publishers, Inc., 1987.
Talo H, Yataco A, Rowe PC, Bou-Holaigah I, Kan J, Kass DA, Berger RA, Calkins H. Comparison of heart rate variability in patients with chronic fatigue syndrome and controls. Clin Autonomic Res 1997; 7:293-7.
Bou-Holaigah I, Calkins H, Flynn J, Tunin C, Chang H, Kan J, Rowe PC. Provocation of hypotension and pain during upright tilt table testing in adults with fibromyalgia. Clin Experimental Rheumatol 1997;15:239-46.
Klassen TP, Watters LK, Sutcliffe T, Rowe PC. The efficacy of nebulized budesonide in dexamethasone-treated outpatients with croup. Pediatrics 1996;97:463-6.
Kelly KJ, Lazenby AJ, Rowe PC, Yardley JH, Perman JA, Sampson HA. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid- based formula. Gastroenterology 1995;109:1503-12.
Bou-Holaigah I, Rowe PC, Kan J, Calkins H. The relationship between neurally mediated hypotension and the chronic fatigue syndrome. JAMA 1995;274;961-7.
Rowe PC, Bou-Holaigah I, Kan JS, Calkins HG. Is neurally mediated hypotension an unrecognized cause of chronic fatigue? Lancet 1995;345:623-4.
Rowe PC, Calkins H, DeBusk K, McKenzie R, Anand R, Sharma G, Cuccherini BA, Soto N, Hohman P, Snader S, Lucas KE, Wolff M, Straus SE. Fludrocortisone acetate to treat neurally mediated hypotension in chronic fatigue syndrome: a randomized controlled trial. JAMA 2001;285:52-59.
King WJ, Schlieper AS, Birdi N, Capelli M, Korneluk Y, Rowe PC. The effect of Kawasaki disease on cognition and behavior. Arch Pediatr Adolesc Med 2000;154:463-8.
Rowe PC, Barron DF, Calkins H, Maumenee IH, Tong PY, Geraghty MT. Ehlers-Danlos syndrome. J Pediatr 1999;135:513.
Rowe PC, Barron DF, Calkins H, Maumenee IH, Tong PY, Geraghty MT. Orthostatic intolerance and chronic fatigue syndrome associated with Ehlers-Danlos syndrome. J Pediatr 1999;135:494-9.
Atiga WL, Rowe P, Calkins H. Management of vasovagal syncope. J Cardiovasc Electrophys 1999;10:874-86.
Rowe PC, Calkins H. Neurally mediated hypotension and chronic fatigue syndrome. Am J Med 1998;105:15S-21S.
Sullivan SD, Hanauer J, Rowe PC, Barron DF, Darbari A, Oliva-Hemker M. Gastrointestinal symptoms associated with orthostatic intolerance. JPGN 2005;40:425-8.
Lucas KE, Rowe PC, Coresh J, Klag MJ, Meoni LA, Ford DE. Prospective association between hypotension and idiopathic chronic fatigue. J Hypertension 2004;22:691-5.
Razumovsky AY, DeBusk K, Calkins H, Snader S, Lucas KE, Vyas P, Hanley DF, Rowe PC. Cerebral and systemic hemodynamics changes during upright tilt in chronic fatigue syndrome. J Neuroimaging 2003;13:57-67.
Hoke TR, Donohue PK, Bawa PK, Mitchell RD, Pathak A, Rowe PC, Byrne BJ. Oxygen saturation as a screening test for critical heart disease. Pediatr Cardiol 2002;23:403-9.
Barron DF, Cohen BA, Geraghty MT, Violand R, Rowe PC. Joint hypermobility is more common in children with chronic fatigue syndrome than in healthy controls. J Pediatr 2002;141:421-5.
Rowe PC. Orthostatic intolerance and chronic fatigue syndrome: new light on an old problem. J Pediatr 2002;140:387-9.
Venbrux AC, Chang AH, Kim HS, Montague BJ, Hebert JB, Arepally A, Rowe PC, Barron DF, Lambert D, Robinson JC. Pelvic congestion syndrome (pelvic venous incompetence): impact of ovarian and internal iliac embolotherapy on menstrual cycle and chronic pelvic pain. J Vasc Interv Radiol 2002;13:171-8.
Rowe PC, Lucas KE. Orthostatic intolerance in chronic fatigue syndrome. Am J Med 2007;120:e13.
Kuo DZ, Cheng TL, Rowe PC. Successful use of a primary care practice-subspecialty collaboration in the care of an adolescent with chronic fatigue syndrome. Pediatrics 2007;120:e1536-e1539.
Lucas KE, Rowe PC, Armenian HK. Latency and exposure-health associations in Gulf War Veterans with early fatigue onsets: a case-control study. Ann Epidemiol. 2007;17:799-806.
Terlou A, Ruble K, Stapert AF, Chang HC, Rowe PC, Schwartz CL. Orthostatic intolerance in survivors of childhood cancer. Eur J Cancer. 2007;43:2685-90.
Lucas KE, Armenian HK, Petersen GM, Rowe PC. Familial aggregation of fainting in a case-control study of neurally mediated hypotension patients who present with unexplained chronic fatigue. Europace. 2006;8:846-51.
Kim HS, Malhotra AD, Rowe PC, Lee JM, Venbrux AC. Embolotherapy for pelvic congestion syndrome: long-term results. J Vasc Interv Radiol 2006;17:289-97.
Lucas KE, Armenian H, DeBusk K, Calkins H, Rowe PC. Characterizing Gulf War illnesses: neurally mediated hypotension and postural tachycardia syndrome. Am J Med 2005;118:1421-27.