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Robert Avery Montgomery, M.D., Ph.D.

Chief, Division of Transplantation
Professor of Surgery

Male

Appointment Phone

410-955-6685

Main Location

Johns Hopkins Outpatient Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Chief, Division of Transplantation
  • Director, Johns Hopkins Comprehensive Transplant Center
  • Professor of Surgery

Centers & Institutes

Departments

Locations

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-6685

601 N. Caroline Street
Baltimore, MD 21287 map
Phone: 410-614-5957

The Johns Hopkins Hospital

Appointment Phone: 410-955-6685

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-614-5957

Expertise

Abdominal Surgery, ABO Incompatible Transplant, Altruistic Donor Programs, Complex Kidney Transplant, HLA Incompatible Transplant, Incompatible Kidney Transplant, Kidney Transplant, Laparoscopic Kidney Surgery, Laparoscopic Live Donor Nephrectomy, Live Donor Kidney Transplant, Live Donor Liver Transplant, Liver Transplant , Minimally Invasive Surgery, Nondirected Kidney Donor Program, Paired Kidney Exchange, Pancreas Transplant, Pancreatic Surgery, Positive Crossmatch Transplant, Reconstruction of Kidney Transplant Ureters, Redo Kidney Transplant, Vascular Surgery

Biography

Dr. Robert A. Montgomery, MD, DPhil, FACS, is the inaugural recipient of the Margery K. and Thomas Pozefsky Endowed Professorship in Kidney Transplantation. He received his doctor of medicine with Honor from the University Of Rochester School Of Medicine. He received his  doctor of philosophy from Balliol College, The University of Oxford, England in molecular immunology. In 2007 he was awarded an honorary doctor of science from his Alma Mater, St Lawrence University. Dr. Montgomery completed his general surgical training, multi-organ  transplantation fellowship and post-doctoral fellowship in human molecular genetics at Johns Hopkins.

Dr. Montgomery was part of the team that developed the laparoscopic procedure for live kidney donation, a procedure that has become the standard throughout the world. He and the Hopkins team conceived the idea of the Domino Paired Donation and the Hopkins protocol for desensitization of incompatible kidney transplant patients. Dr. Montgomery participated in the first chain of transplants started by an altruistic donor. He led the team that performed the first 2-way domino paired donation, 3-way paired donation, 3-way domino paired donation, 4-way paired donation, 4-way domino paired donation, 5-way domino paired donation, 6-way domino paired donation, 8-way multi-institutional  domino paired donation, and co-led the first 10-way open chain. He is credited in the 2010 Guinness Book of World Records with the most kidney transplants performed in one day. Dr. Montgomery is considered a world expert on kidney transplantation for highly sensitized and ABO incompatible patients. His work with patients in these programs has been featured on the Today Show, Good Morning America, the CBS, ABC and NBC Evening News, CNN, The Discovery Channel, USA Today, and the front page of The New York Times, Wall Street Journal, and The Washington Post.

Dr. Montgomery has received important awards and distinctions including a Fulbright Scholarship and a Thomas J. Watson Fellowship and  memberships in the Phi Beta Kappa and Alpha Omega Alpha academic honor societies. He has been awarded multiple scholarships from The American College of Surgeons and The American Society of Transplant Surgeons. The National Kidney Foundation of Maryland has recognized his contributions to the field of transplantation with the Champion of Hope Award and the National Kidney Registry recognized him with the Terasaki Medical Innovation Award.

 

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Featured Video

Kidney Transplant ACCEPTOR Clinical Trial | Q&A

More Videos

    Additional Information

  • Education +

    Degrees

    • University of Rochester / MD (1987)

    Residencies

    • Johns Hopkins University School of Medicine / Surgery (1995)

    Certifications

    • American Board of Surgery / Surgery (1996, 2006)
  • Research & Publications +

    Research Summary

    Dr. Montgomery is a co-principal investigator for an NIH/ITN sponsored tolerance clinical trial for simultaneous donor bone marrow and live donor kidney transplantation. He runs multiple investigator initiated clinical trials of novel desensitization therapies. His research interests include mechanisms underlying the immunomodulatory effect of plasmapheresis, stem cell therapy for highly sensitized patients, and gene and cell based therapies in transplantation.

    Clinical Trials:

    ACCEPTOR Clinical Trial for Kidney Transplant Recipients

    The purpose of this study is to find out if the study treatment will allow people to accept their new kidney and be able to stop taking anti-rejection medications.


    Selected Publications

    Montgomery RA, Lonze BE, King KE, Kraus ES, Kucirka LM, Locke JE, Warren DS, Simpkins CE, Dagher NN, Singer AL, Zachary AA, Segev DL. Desensitization of HLA-Incompatible Kidney Recipients and Survival. N Engl J Med. 2011 July 28;365(4):318-326.

    Rees MA, Kopke JE, Pelletier RP, Segev DL, Rutter ME, Fabrega AJ, Rogers J, Pankewycz OG, Hiller J, Roth AE, Sandholm T, Unver MU, Montgomery RA. A nonsimultaneous, extended, altruistic-donor chain. N Engl J Med. 2009 March 12;360(11):1096-1101.

    Montgomery RA, Zachary AA, Ratner LE, Segev DL, Hiller JM, Houp J, Cooper M, Kavoussi L, Jarrett T, Burdick J, Maley WR, Melancon JK, Kozlowski T, Simpkins CE, Phillips M, Desai A, Collins V, Reeb B, Kraus E, Rabb H, Leffell MS, Warren DS. Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation. JAMA. 2005 Oct 5;294(13):1655-63.

    Segev DL, Gentry SE, Warren DS, Reeb B, Montgomery RA. 2005. Kidney Paired Donation and Optimizing the Use of Live Donor Organs. JAMA 293(15):1883-90.

    Montgomery RA, Gentry SE, Marks WH, Warren DS, Hiller J, Houp J, Zachary AA, Melancon JK, Maley WR, Rabb H, Simpkins C, Segev DL. Domino paired kidney donation: A strategy to make best use of live non-directed donation. Lancet. 2006 July 29;368(9533):419-421.

    Segev DL, Muzaale AD, Caffo BS, Mehta SH, Singer AL, Taranto SE, McBride MA, Montgomery RA. Perioperative mortality and long-term survival following live kidney donation. JAMA. 2010 March 10;303(10):959-966.

    Frischmeyer-Guerrerio PA*, Montgomery RA*, Warren DS, Cooke SK, Lutz J, Sonnenday CJ, Guerrerio AL, Dietz HC. Perturbation of Thymocyte Development in Nonsense Mediated Decay-Deficient Mice. PNAS 2011 June 28;108(26):10638-10643.* Equal Contributors.
    Lonze BE, Singer AL, Montgomery RA. Eculizumab and renal transplantation in a patient with CAPS. N Engl J Med. 2010 May 6;362(18):1744-1745.

    Alachkar N, Gupta G, Montgomery RA. Angiotensin antibodies and focal segmental glomerulosclerosis. N Engl J Med. 2013 Mar 7;368(10):971-3.

    Kucirka LM, Grams ME, Lessler J, Hall EC, James N, Massie AB, Montgomery RA, Segev DL. Association of race and age with survival among patients undergoing dialysis. JAMA. 2011 August 10;306(6):620-626.

    Muzaale AD, Massie AB, Wang MC, Montgomery RA, McBride MA, Wainright JL, Segev DL. Risk of end-stage renal disease following live kidney donation. JAMA. 2014 Feb 12;311(6):579-86.

    Ratner LE, Kavoussi LR, Sroka M, Hiller J, Weber R, Schulam PG, Montgomery RA. Laparoscopic assisted live donor nephrectomy: a comparison with the open approach. Transplantation. 1997 63(2): 229-233.

    Montgomery RA, Zachary AA, Racusen LL, Leffell MS, King KE, Burdick J, Maley WR, Ratner LE. Plasmapheresis and intravenous immune globulin provides effective rescue therapy for refractory humoral rejection and allows kidneys to be successfully transplanted into crossmatch-positive recipients. Transplantation 2000. 70(6): 887-895.

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    • Alpha Omega Alpha Honor Society
    • American College of Surgeons scholarship
    • American Society of Transplant Surgeons scholarship
    • Fulbright Scholarship
    • Phi Beta Kappa Honor Society
    • Thomas J. Watson Fellowship
  • Videos & Media +

    Videos

    Johns Hopkins Medicine Incompatible Kidney Transplant Program. Valentine's Day Kidney Swap 2009

    Meet Dr. Montgomery

    What Makes the Comprehensive Transplant Center Unique?

    Kidney Transplants- Even if Patients are Incompatible

    Meet Our Expert: Dr. Robert Montgomery

    Pamela Paulk's Kidney Donation at Johns Hopkins Medicine

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