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School of Medicine
Thomas J K Tung, M.D.
Professor of Anesthesiology and Critical Care Medicine
Languages: English, Chinese, Japanese
Research Interests: Regulation of intracranial pressure by intrathoracic pressure; Global brain ischemia; Spinal cord ischemia; Focal cerebral ischemic injury; Effects on edema in the brain; Osmotic therapy for stroke ...read more
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The Johns Hopkins Hospital
Appointment Phone: 410-955-2611
600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Dr. Thomas Toung is a professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine.
Dr. Toung has several research interests involving experimental animal models, including osmotic therapy for stroke and effects on edema in brain, lung and peripheral organs.
He received his undergraduate degree from The College of Science at National Taiwan University and earned his M.D. from National Taiwan University. He completed his residency at St. Francis Hospital in Wichita, Kansas, and performed a fellowship in general surgery at Massachusetts General Hospital. Dr. Toung joined the Johns Hopkins faculty in 1971.
- Professor of Anesthesiology and Critical Care Medicine
- Joint Appointment in Neurosurgery
- National Taiwan University Medical School (1960)
- American Board of Anesthesiology / Anesthesiology (1970)
Research & Publications
Dr. Toung has several research interests involving experimental animal models, including osmotic therapy for stroke and effects on edema in brain, lung and peripheral organs. He has found that hypertonic saline can be administered to reduce severe brain swelling after experimental stroke and that water content is influenced in other organs.
He has also been studying the role of sex hormones on focal cerebral ischemic injury and whether injection of a clot to occlude the middle cerebral artery produces varying degrees of injury in male and female animals. Other research has focused on spinal cord ischemia, global brain ischemia and regulation of intracranial pressure by intrathoracic pressure.
- Toung TJ, Nyquist P, Mirski MA. "Effect of hypertonic saline concentration on cerebral and visceral organ water in an uninjured rodent model." Crit Care Med. 36(1):256–61, 2008.
- Ziai WC, Toung TJ, Bhardwaj A. "Hypertonic saline: first-line therapy for cerebral edema?" J Neurol Sci. 261(1-2):157–66, 2008.
- Mirski MA, Lele AV, Fitzsimmons L, Toung TJ. "Diagnosis and treatment of vascular air embolism." Anesthesiology 106(1):164–77, 2007.
- Toung TJ, Chen CH, Lin C, Bhardwaj A. "Osmotherapy with hypertonic saline attenuates water content in brain and extracerebral organs." Crit Care Med. 35(2):526–31, 2007.
- Lee EJ, Lee MY, Shyr MH, Cheng JT, Toung TJ, Mirski MA, Chen TY. "Adjuvant bupivacaine scalp block facilitates stabilization of hemodynamics in patients undergoing craniotomy with general anesthesia: a preliminary report." J Clin Anesth. 18(7):490–4, 2006.