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James C O Harris, MD

Director, Developmental Neuropsychiatry Clinic
Professor of Psychiatry and Behavioral Sciences
Male
Appointment Phone

410-614-2401

Main Location

The Johns Hopkins Hospital

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Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Developmental Neuropsychiatry Clinic
  • Professor of Psychiatry and Behavioral Sciences
  • Professor of Pediatrics

Centers & Institutes

  • Children's Mental Health Center

Expertise

Adult Psychiatry, Child and Adolescent Psychiatry, Child Development and Behavioral Health, Lesch-Nyhan Disease, Neurodevelopmental Disorders, Psychiatry

Research Interests

Neurogenetic syndromes, autism, ADHD, Sleep Disorders

Biography

1976 Director of Developmental Neuropsychiatry, The Johns Hopkins University School of Medicine
1976-1992 Director of Developmental Neuropsychiatry Kennedy Krieger Institute
1978 1982 Interim Director, Division of Child Psychiatry, Johns Hopkins University School of Medicine
1978 1982 Director Consultation/ Liaison, Division of Child Psychiatry, Johns Hopkins University School of Medicine
1978 1984 Adjunct Scientist, Laboratory of Brain Evolution and Behavior, Poolesville, MD (Paul MacLean, M. D., Chief)
1982 1989 Director of Education, Division of Child Psychiatry, Johns Hopkins University
1983 Co-Founder Autism Clinic, Kennedy Krieger Institute
1984 1992 Adjunct Scientist Laboratory of Comparative Ethology (Steven Suomi, Ph.D., Chief)
1986 1988 President of the Medical Staff (First Elected President), Kennedy Krieger Institute
1992 U. S. Representative, Society for the Study of Behavioral Phenotype
1998 2000 President, Society for Professors of Child & Adolescent Psychiatry
1998 Visiting Professor, Guys and St. Thomas Hospitals, London
2001 2002 Visiting Scholar, University of Chicago (Dept. of Psychiatry: Institute of Mind and Biology)

Languages

  • English
  • Thai

Memberships

1978- Member, American Psychiatric Association
Fellow, American Psychiatric Association (1993)
Life Fellow, American Psychiatric Association (2007)

1978- Member, Maryland Psychiatric Society

1980- Member, American Academy of Child and Adolescent Psychiatry

1983- Member, American Association of Directors of
Psychiatric Residency Training
1983- Member, American Association for the Advancement of Science

1984- Member, Society for Neuroscience

1985- Fellow, American Academy of Child/Adolescent Psychiatry

1984- Member, American Sleep Disorders Association/Society for Sleep Research


1986-88 President, Maryland Regional Council for Child and
Adolescent Psychiatry

1987- Member, Academy of Psychiatry and the Law

1992- United States Representative, International Society for the Study
of Behavioral Phenotypes

1993- Member, New York Academy of Medicine

1995- Member, American Society of Clinical Psychopharmacology


1998-2000 President, Society of Professors of Child and Adolescent
Psychiatry

Clinical Trial Keywords

  • Neurodevelopmental Disorders

Additional Resources

Additional Resources +
  • Education +

    Training

    • George Washington University School of Medicine ( Washington DC ) (1966)

    Certifications

    • Child and Adolescent Psychiatry, American Board of Psychiatry & Neurology (1981)
    • Psychiatry, American Board of Psychiatry & Neurology (1980)
    • Pediatrics, American Board of Pediatrics (1974)
  • Research & Publications +

    Research Summary

    My research is in Developmental Neuropsychiatry, focused on behavioral phenotypes in neurogenetic disorder. I have authored a textbook written to establish this field as subspecialty in psychiatry. This two volume book was chosen as medical book of the year among 2500 medical books in 76 specialties in the year of publication. The NIH awarded me support through an R-01 to study Lesch-Nyhan disease. Psychopharmacology in Neurodevelopmental disorders is another area of research interest. I am a fellow of the American College of Neuropsychopharmacology. I work as the cover editor for the journal JAMA Psychiatry for the Art and Images section and choose the cover each month and write a commentary about a psychiatric theme represented in this work. In the general department I teach a course on personality that focuses on the work of Adolph Meyer,  Erik Erikson, John  Bowlby and Carl Jung. I write the psychiatry section for the Oski Textbook of Pediatrics (now in the third edition) and the section of purine and pyrimidines for the Nelson Textbook of Pediatrics.

    Selected Publications

    1. Harris JC Behavioral phenotypes of neurodevelomental disorders: portals into the developing brain. In Davis,KL Coyle,JT, Charney,D and Nemeroff C. (eds.), Psychopharmacology: the Fifth Generation of Progress, American College of Psychopharmacology, Nashville, TN, 2001.
    2. Horska, A., Kaufmann, W. E., Brant, L. J., Naidu, S., Harris, J. C., and Barker, P. B. 2002. In vivo quantitative proton MRSI study of brain development from childhood to adolescence. J Magn Reson Imaging, 15(2):137-143. 
    3. Harris, J.C. Social Neuroscience, integrated brain function, empathy and neurodevelopmental disorders. Physiology and Behavior. 79(3):525-31, 2003.
    4. Fairbanks LD, Harris JC, Duley JA, Simmonds HA. Nucleotide degradation products in cerebrospinal fluid (CSF) in inherited and acquired pathologies. Nucleosides Nucleotides Nucleic Acids. 23:1185-1187, 2004.
    5. De Gregorio L, Jinnah HA, Harris JC, Nyhan WL, Schretlen DJ, Trombley LM,O''Neill JP. Lesch-Nyhan disease in a female with a clinically normal monozygotic twin.Mol Genet Metab. 85:70-7, 2005 

      B. Selected Publications

    6. Schretlen DJ, Ward J, Meyer SM, Yun J, Puig JG, Nyhan WL, Jinnah HA, Harris JC. Behavioral aspects of Lesch-Nyhan disease and its variants. Dev Med Child Neurol. 47:673-677, 2005
    7. Jinnah HA, Visser JE, Harris JC, Verdu A, Larovere L, Ceballos-Picot I et al Delineation of the motor disorder of Lesch-Nyhan disease. Brain. 129(Pt 5):1201-1217, 2006
    8. Harris, JC. (2007)The evolutionary biology, emergence, and facilitation of empathy. In Farrow, M. (ed) Empathy and Mental Illness. Cambridge University Press. Cambridge, England. 
    9. Harris, JC. . (2007) Psychiatric Disorders in Persons with Intellectual Disability. In Gabbard, G. (ed) Treatments of Psychiatric Disorders,American Psychiatric Association Press, Washington, D. C Harris, JC., 2007
    10. Harris, JC. Disorders of Purine and Pyrimidine Metabolism In Kliegman, R.M., Behrman, R.E, . Jenson, H.B. and Stanton, B. Nelson Textbook of Pediatrics,18th Edition. W.B. Saunders, Philadelphia, 2007.
    11. Harris, J.C. Developmental Neuropsychiatric Disorders. In New Oxford Textbook of Psychiatry. Gelder, M. , Lopez-Ibor, JJ, Andreasen, N. (eds) Oxford University Press. Oxford, U.K. 2009
    12. Harris, JC. Brain Disorders and their effect on psychopathology. In Rutter, M. (ed). Rutters Textbook of Child and Adolescent Psychiatry. Blackwell, London. 2008
    13. Hong CC, Harris JC, Pearlson GD, Kim JS, Calhoun VD, Fallon JH, Golay X, Gillen JS, Simmonds DJ, van 
    14. Zijl PC, Zee DS, Pekar JJ. fMRI evidence for multisensory recruitment associated with rapid eye movements during sleep.Hum Brain Mapp. 2009 Oct 28. [Epub ahead of print]
    15. Books, Series Editorships, and Monthly Commentaries
    16. Harris J. (1998). Developmental neuropsychiatry. Volume 1: Fundamentals of developmental neuropsychiatry. Volume 2: Assessment, diagnosis and treatment of the developmental disorders. Oxford University Press, New York. (Medical Book of the Year, 1995)
    17. Harris, J. (2006). Intellectual Disability: Understanding Its Development, Causes, Classification, Evaluation, and Treatment. Oxford University Press, New York.
    18. Harris, J. Book Series Editor, Developmental Perspectives in Psychiatry. Oxford University Press.
    19. Harris, J. Art and Images Editor. Archives of General Psychiatry. Monthly Commentaries on Art and Science.. (75 commentaries published 2002-January 2009 in 10 topic areas)



    C. RESEARCH SUPPORT

    Recently Completed Research Support
    R01 HD33095 (Harris, PI) 4/8/973/31/01
    NIH/NICHD
    Behavior and Neurobiological Correlates of HPRT Deficiency
    This study aimed to quantify behavioral, cognitive, and neuroanatomic aspects of HPRT deficiency

    (Harris, PI) 11/6/972/1/06
    Lesch-Nyhan Syndrome Childrens Research
    MRI and PET studies of Lesch-Nyhan disease

    Current Research Support.

    Lesch-Nyhan Disease: Neuroanatomical and Biochemical
    Bases of the Phenotype 1 R01 HD053312-01A2 2008-2012
    Schrelen (PI.) Harris (co-investigator)

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Honors
    Outstanding Teacher Award (1989, 1996, 1998, 1999); Sabbatical Year (Full-Time) (1992-93)
    Whos Who in America 2002-,. Whos Who in the World, 2002-, Medical Book of the Year (1995): Developmental Neuropsychiatry (2 vols. Single Author), Fellow, American College of Neuropsychopharmacology (2002-). 2003-American College of Psychiatrists.2007 APA Agnes Purcell McGavin Award for Distinguished Career Achievement in Child and Adolescent Psychiatry.

    Professional Activities

    Honors
    Outstanding Teacher Award (1989, 1996, 1998, 1999); Sabbatical Year (Full-Time) (1992-93)
    Whos Who in America 2002-,. Whos Who in the World, 2002-, Medical Book of the Year (1995): Developmental Neuropsychiatry (2 vols. Single Author), Fellow, American College of Neuropsychopharmacology (2002-). 2003-American College of Psychiatrists.2007 APA Agnes Purcell McGavin Award for Distinguished Career Achievement in Child and Adolescent Psychiatry.
    Board Certification
    American Board of Pediatrics (1974); American Board of Psychiatry and Neurology (Psychiatry, 1980);
    American Board of Psychiatry and Neurology (Child Psychiatry, 1981)
    Editorial Boards
    Archives of General Psychiatry (Art and Images editor-2002-present), Journal of Child Neurology (2001-2007)
  • Videos & Media +
  • Upcoming Events +
  • Contact & Locations +

    Locations

    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-614-2401
    Appointment Phone: 410-614-2401
    Fax: 410-955-8691
    Location Map

    Department/Division

    • Psychiatry and Behavioral Sciences - Developmental Neuropsychiatry

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