Brigitte Maria Ronnett, M.D.

Headshot of Brigitte Maria Ronnett
  • Co-director, Johns Hopkins Gynecologic Pathology Consultation Service
  • Professor Emerita of Pathology
Female

Expertise

Pathology

Research Interests

Gynecologic pathology; molecular diagnosis of molar pregnancy; pathology of ovarian mucinous neoplasms; clinicopathological characterization of gynecologic neoplasms ...read more

Locations

The Johns Hopkins Hospital

401 North Broadway
Pathology, Weinberg Building, Suite 2242
Baltimore, MD 21231-2410
Phone: 410-614-2971
The Johns Hopkins Hospital - Google Maps

Background

Dr. Brigitte M. Ronnett is Professor of Pathology and Gynecology & Obstetrics at The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD. She is a diagnostic pathologist and clinical researcher whose accomplishments in clinical service, education and research have established her as a nationally and internationally recognized expert in gynecologic pathology. Dr. Ronnett graduated from Northwestern University, Evanston, IL (B.A. chemistry, 1982). She received her medical degree from the University Of Chicago Pritzker School Of Medicine, Chicago, IL (M.D., 1986). She completed residency training in anatomic and clinical pathology at The Johns Hopkins Hospital, Baltimore, MD, (anatomic: 1986-1989; clinical: 1991-1993). She also completed a 1-year surgical pathology fellowship at Memorial Sloan-Kettering Cancer Center, New York, NY (1989-1990) and a 1-year surgical pathology fellowship/chief residency at The Johns Hopkins Hospital, Baltimore, MD (1990-1991). She then completed a 2-year subspecialty fellowship in gynecologic pathology at The Johns Hopkins Hospital, Baltimore, MD (1993-1995). She joined the faculty of the Department of Pathology at The Johns Hopkins Hospital in 1995 and achieved the rank of Full Professor in 2007. Her clinical efforts are focused on a large gynecologic pathology consultation practice at The Johns Hopkins Hospital. Her research efforts have focused on the following topics: 1. Ovarian mucinous tumors, with emphasis on distinction of primary and metastatic mucinous tumors in the ovaries and clarifying the origin of pseudomyxoma peritonei in women. 2. Clinicopathologic studies on various gynecologic tract tumors, with emphasis on utility of ancillary techniques for diagnosis. 3. Hydatidiform moles and gestational trophoblastic tumors, with emphasis on molecular analysis for refined diagnosis. 4. Collaborative funded studies on HPV-associated cervical/anogenital lesions, functioning as a nationally recognized expert for adjudicating anogenital biopsy diagnoses.

...read more

Titles

  • Co-director, Johns Hopkins Gynecologic Pathology Consultation Service
  • Professor Emerita of Pathology
  • Professor Emerita of Gynecology and Obstetrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Medicine; University of Chicago Pritzker School of Medicine (1986)

Residencies

  • Anatomic Pathology; Johns Hopkins University School of Medicine (1989)
  • Pathology Laboratory Medicine; Johns Hopkins University School of Medicine (1993)

Fellowships

  • Surgical Pathology; Johns Hopkins University School of Medicine (1990)
  • Gynecologic Pathology; Johns Hopkins University School of Medicine (1995)
  • Pathology; Memorial Sloan Kettering Cancer Center (1990)

Board Certifications

  • American Board of Pathology (Anatomic Pathology) (1991)
  • American Board of Pathology (Clinical Pathology) (1993)

Research & Publications

Research Summary

Dr. Ronnett is a diagnostic pathologist and clinical researcher whose accomplishments in clinical service, education, and research have established her as a nationally and internationally recognized expert in gynecologic pathology. As a clinical researcher, her work has addressed a wide variety of topics in gynecologic pathology. Within this specialty, her research efforts have focused on the following topics:

  1. Ovarian mucinous tumors, with emphasis on distinction of primary and metastatic mucinous tumors in the ovaries.
  2. Clinicopathologic studies on various gynecologic tract tumors, with emphasis on utility of ancillary techniques for diagnosis.
  3. Hydatidiform moles and gestational trophoblastic tumors, with emphasis on molecular analysis for refined diagnosis.
  4. Collaborative funded studies on HPV-related cervical/anogenital lesions, functioning as a nationally recognized expert for adjudicating anogenital biopsy diagnoses.

Studies on ovarian mucinous tumors have contributed to refined diagnosis of these tumors, clarification of their behavior and relationship to pseudomyxoma peritonei,and improved recognition of metastatic tumors in the ovary that simulate primary ovarian tumors. Studies on hydatidiform moles have highlighted the persistent problem of imperfect diagnostic reproducibility, demonstrated the value of ancillary techniques (p57 immunohistochemistry and DNA genotyping) for refining diagnosis, and characterized interesting and unusual molar entities.

Selected Publications

View all on PubMed

Ronnett BM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to pseudomyxoma peritonei. Am J Surg Pathol 1995;19(12):1390-1408. PMID: 7503361

Ronnett BM. Endocervical adenocarcinoma: selected diagnostic challenges. Mod Pathol 2016;29(Suppl 1):S12-28. PMID: 26715171

Ronnett BM. Hydatidiform moles: ancillary techniques to refine diagnosis. Arch Pathol Lab Med 2018;142(12):1485-1502. PMID: 30500280

Kurman RJ, Ellenson LH, Ronnett BM (eds), Blaustein's Pathology of the Female Genital Tract, 7th ed., New York, NY: Springer Verlag, 2019.

Xing D, Adams E, Huang J, Ronnett BM. Refined diagnosis of hydatidiform moles with p57 immunohistochemistry and molecular genotyping: updated analysis of a prospective series of 2,217 cases. Mod Pathol 2021;34(5):961-982. PMID: 33024305

Activities & Honors

Memberships

  • United States and Canadian Academy of Pathology
  • International Society of Gynecological Pathologists
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