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Susan B Bressler, M.D.

Photo of Dr. Susan B Bressler, M.D.

Professor of Ophthalmology

Female

Expertise: Arterial Occlusive Disease, Diabetic Retinopathy, Macular Degeneration, Age-Related, Macular Disorders, Ophthalmology, Retina, Medical Diseases, Venous Occlusive Disease ...read more

Research Interests: Clinical trials; Age-Related Macular Degeneration; Diabetic Retinopathy; Venous Occlusive Disease; Ocular Imaging

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Locations

Johns Hopkins Wilmer Eye Institute
Appointment Phone: 410-955-3518

600 N. Wolfe Street
Baltimore, MD 21287 map
Phone: 410-955-3648
Fax: 410-614-3011

Background

Dr. Susan Bressler is the Julia G. Levy, Ph.D. Professor of Ophthalmology at the Wilmer Eye Institute. She is a board-certified ophthalmologist and has subspecialty training in medical retinal disorders, vitreoretinal disease, and retinal surgery. Her main research interest has been collaborative efforts in clinical trials - serving as principal investigator of an image reading center that has served as a central unit for many clinical trials and epidemiologic investigations, as Vice Chair of the Diabetic Retinopathy Clinical Research Network and as principal investigator of a participating clinical center in several major clinical trials. Most studies have specific emphasis on the treatment of both non-neovascular and neovascular age-related macular degeneration and all aspects of diabetic retinopathy. 

Dr. Bressler has a large national and international referral practice. In addition, she has published 223 peer reviewed articles and 55 book chapters. Editorial Board positions have included American Journal of Ophthalmology, Survey of Ophthalmology, Retina, EyeNet Magazine, Health After 50: The Johns Hopkins Medical Letter and the Wilmer Retina Update.

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Titles

  • Professor of Ophthalmology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Medicine, Johns Hopkins University School of Medicine (1982)

Residencies

  • Harvard Medical School / Ophthalmology (1986)

Fellowships

  • Johns Hopkins University School of Medicine (1987)

Board Certifications

  • American Board of Ophthalmology / Ophthalmology (1987)

Research & Publications

Technology Expertise Keywords

Age-related Macular Degeneration (Non-neovascular [Dry, Atrophic] and Neovascular AMD; Diabetic Retinopathy (Diabetic Macular Edema, Non-proliferative and Proliferative Retinopathy; Venous Occlusive Disease (Central and Branch Retinal Vein Occlusion); Other macular disorders (Epiretinal membrane, Macular Holes, Central Serous Retinopathy, Pattern Dystrophy, Pathologic Myopia; Choroidal Neovascularization; Arterial Occlusive Disease

Clinical Trial Keywords

Diabetic Retinopathy, Age-Related Macular Degeneration

Selected Publications

View all on Pubmed

Bressler SB, Bressler NM. Dick Green Tribute. Retina 2005;25:S1-S28.

VIP Report No. 5 Writing Committee. Letter to Editor. Verteporfin in Photodynamic Therapy: report no. 5 (Dr. Bressler is a member of the VIP study group.) Ophthalmology 2004;111:2144.

Cukras C, Agron E, Klein M, Ferris FL, et. al for the Age-Related Eye Disease Study Research Group. Natural History of Drusenoid Pigment Epithelial Detachment in Age-Related Macular Degeneration: Age-Related Eye Disease Study Report No, 28: Ophthalmology 2010; 117(3):489-499. (Dr. Susan Bressler is a member of the AREDS research group.)

The Diabetic Retinopathy Clinical Research Network, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, et al. Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema. Ophthalmology. 2010 Jun;117(6):1064-1077.

Diabetic Retinopathy Clinical Research Network Writing Committee on behalf of the DRCR.net. Vitrectomy Outcomes in Eyes with Diabetic Macular Edema and Vitreomacular Traction. (Dr. Bressler is a Vice Chair of the DRCR.net) Ophthalmology. 2010 Jun;117(6):1087-1093.

Chang MA, Do DV, Bressler SB, Cassard SD, Gower EW and Bressler NM: Prospective 1-Year Study of Ranibizumab for Predominantly Hemorrhagic Chorodial Neovascular Lesions in Age-Related Macular Degeneration. Retina 2010 Sep; 30 (8):1171-1176.

Flaxel CJ, Edwards AR, Aiello LP, Arrigg PA, Beck RW, Bressler NM, Bressler SB, et al: Factors Associated with Visual Acuity Outcomes after Vitrectomy for Diabetic Macular Edema. Retina 2010: 30:1488–1495.

Flaxel CJ, Edwards AR, Aiello LP, Arrigg PA, Beck RW, Bressler NM, Bressler SB, et al: Factors Associated with Visual Acuity Outcomes after Vitrectomy for Diabetic Macular Edema. Retina 2010: 30:1488–1495

Swenor BK, Bressler SB, Caulfield L, West SK: The Impact of Fish and Shellfish Consumption on Age-Related Macular Degeneration. Ophthalmology. 2010 Dec;117(12):2395-401.

Danis RP, Scott IU, Bressler SB, Bressler NM, Browning DJ and the Diabetic Retinopathy Clinical Research Network Study Group: Association of Fluorescein Angiographic Features with Visual Acuity and with Optical Coherence Tomographic and Stereoscopic Color Fundus Photographic Features of Diabetic Macular Edema in a Randomized Clinical Trial. Retina. Nov-Dec 2010;30(10):1627-37.

Diabetic Retinopathy Clinical Research Network Writing Committee on behalf of the DRCR.net. Expanded 2-Year Follow-up of Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema. (Dr. Bressler is a Vice Chair of the DRCR.net.) Ophthalmology 2011 April: 118(4): 609-614.

Googe J, Brucker AJ, Bressler NM, Qin H, Aiello LP, Anroszyk A, Beck RW, Bressler SB, et al: Randomized Trial Evaluating Short-Term Effects of Intravitreal Ranibizumab or Triamcinolone Acetonide on Macular Edema After Focal/Grid Laser For Diabetic Macular Edema in Eyes Also Receiving Panretinal Photocoagulation, Retina 2011 31(6)1009-27.

Gangaputra S, Almukhtar T, Glassman A, Aiello LP, Bressler NM, Bressler SB, et al: Comparison of Film and Digital Fundus Photographs in Eyes of Individuals with Diabetes Mellitus. IOVS 2011 Aug; 52:6168-73.

Lopes M, Bressler NM, Zayit-Soudry S, Moshiri A, Bressler SB: Understanding and Reporting Visual Acuity Measurements in Publications of Clinical Research, Arch of Ophthal Sep 2011;129:1228-1229.

Diabetic Retinopathy Clinical Research Network Writing Committee on behalf of the DRCR.net (Dr. Bressler served as a Vice Chair of the DRCR.net during this project): Rationale for the Diabetic Retinopathy Clinical Research Network Treatment Protocol for Center-Involved Diabetic Macular Edema. Ophthalmology 2011 Dec; 118 (12): e5-e14.

Sun JK, Qin H, Aiello LP, et al for the Diabetic Retinopathy Clinical Research Network: Evaluation of Visual Acuity Measurements After Autorefraction vs Manual Refraction in Eyes With and Without Diabetic Macular Edema. (Dr. Bressler served as a Vice Chair of the DRCR.net during this project) Arch Ophthal 2012; 130: 470-479.

Do DV, Gower EW, Boyer D, Bressler N, Bressler S, et al for the AMD DOC Study Group: Detection of New Onset Choroidal Neovascularization using Optical Coherence Tomography: the AMD DOC Study. Ophthalmology 2012 Apr; 119 (4): 771-778.

Bressler SB, Qin H, Beck RW, et al for the Diabetic Retinopathy Clinical Research Network: Factors Associated With Changes in Visual Acuity and Central Subfield Thickness at 1 Year After Treatment for Diabetic Macular Edema With Ranibizumab. Arch Ophthal 2012; 130(9): 1153-61.

Bressler NM, Miller KM, Beck RW, Bressler SB, et al for the Diabetic Retinopathy Clinical Research Network: Observational study of subclinical diabetic macular edema. Eye (London) 2012; 26: 833-840.

Campbell JP, Bressler SB, Bressler NM: Impact of Availability of Anti-VEGF Therapy on Vision Impairment and Blindness due to Neovascular AMD. Arch Ophthal 2012; 130(6): 794-795.

The Age-Related Eye Disease Study 2 (AREDS2) Research Group: Study Design and Baseline Characteristics. AREDS2 Report Number 1. (Dr. Bressler is a Principal Investigator within the AREDS2 Research Group) Ophthalmology 2012 Nov; 119 (11): 2282-89.

Diabetic Retinopathy Clinical Research Network (Dr. Bressler served as Vice Chair of the DRCR.net during this trial): Three-Year Follow-up of a Randomized Trial Evaluating Ranibizumab Plus Prompt versus Deferred Laser for Diabetic Macular Edema. Ophthalmology 2012 Dec; 119(11): 2312-18.

Diabetic Retinopathy Clinical Research Network. (Writing Committee: Chalam KV, Bressler SB, Edwards AR, et al) Retinal Thickness in People with Diabetes and Minimal or No Diabetic Retinopathy: Heidelberg Spectralis Optical Coherence Tomography. IOVS Dec 2012; 53(13): 8154-61.

Diabetic Retinopathy Clinical Research Network (Dr. Bressler served as Vice Chair of the DRCR.net during this trial): Randomized Clinical Trial Evaluating Intravitreal Ranibizumab or Saline for Vitreous Hemorrhage From Proliferative Diabetic Retinopathy. JAMA Ophthalmol. 2013; 131(3):283-293.

Bressler SB, Almukhtar T, Aiello LP, et al, for the Diabetic Retinopathy Clinical Research Network: Green or Yellow Laser Treatment for Diabetic Macular Edema: Exploratory Assessment within the Diabetic Retinopathy Clinical Research Network. Retina 2013: 10: 2080-2088.

Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration. The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial. (Dr. Bressler is a Principal Investigator within the AREDS2 Research Group and served on the writing committee for this paper.) JAMA. May 2013; 309(19): 2005-15.

The Age-Related Eye Disease Study 2 (AREDS2) Research Group: Lutein/Zeaxanthin for the Treatment of Age-Related Cataract: AREDS2 Randomized Trial Report No. 4. (Dr. Bressler is Principal Investigator within the AREDS2 Research Group and is a member of the writing committee for this paper). JAMA Ophthalmol. 2013; 131(7):843-50.

Diabetic Retinopathy Clinical Research Network (Dr. Bressler served as Vice Chair of the DRCR.net during this project): Macular Edema After Cataract Surgery in Eyes Without Pre-operative Central-involved Diabetic Macular Edema. JAMA Ophthalmol. 2013; 131(7): 870-879.

Bressler SB, Qin H, Melia M, Bressler NM, Beck RW, et al for the Diabetic Retinopathy Clinical Research Network: Exploratory Analysis of Effect of Intravitreal Ranibizumab or Triamcinolone on Worsening of Diabetic Retinopathy in a Randomized Clinical Trial. JAMA Ophthalmol 2013;131(8):1033-40.

The Age-Related Eye Disease Study 2 (AREDS2) Research Group: Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). (Dr. Bressler is a member of the writing committee for this paper and Principal Investigator within the AREDS2 Research Group). Invest Ophthalmol Vis Sci. 2013;54(7):4548-54.

AREDS2-HOME Study Research Group: Randomized Trial of a Home Monitoring System for Early Detection of Choroidal Neovascularization Home Monitoring of the Eye (HOME) Study. (Writing Committee: Chew E, Clemons TE, Bressler SB, Elman, MJ; Danis RP, et al.). Ophthalmology Feb 2014; 12(2), 535-544.

The Age-Related Eye Disease Study 2 (AREDS2) Research Group: Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression. AREDS2 Report No. 3. (Dr. Bressler is a member of the writing committee for this paper and Principal Investigator within the AREDS2 Research Group). JAMA Ophthal 2014; 132(2): 142-149.

Diabetic Retinopathy Clinical Research Network. (Writing Committee: Bressler SB, Baker CW, Almukhtar T, Bressler NM, Glassman AR et al): A Pilot Study of Individuals with Diabetic Macular Edema undergoing Cataract Surgery. JAMA Ophthalmol. 2014; 132(2): 224-226.

AREDS2-HOME Study Research Group. Randomized Trial of the ForeseeHome Monitoring Device for Early Detection of Neovascular Age-Related Macular Degeneration.The HOme Monitoring of the Eye (HOME) Study Design- HOME Study Report Number 1 (Writing Committee: Chew E, Clemons TE, Bressler SB, Elman, MJ; Danis RP, et al.) Contemp Clin Trials. 2014 Feb 13;37(2):294-300.

Liu M, Wolfson Y, Bressler S, Do D, Ying H, Bressler N: Comparison of Time- and Spectral-Domain Optical Coherence Tomography in Management of Diabetic Macular Edema. Invest Ophthalmol Vis Sci March 2014 55:1370-1377.

Do D, Bressler S, Cassarde S, Gower E, Tabandeh H, et al: Ranibizumab for Macular Telangiectasia Type 2 in the Absence of Subretinal Neovascularization. Retina Oct 2014;(34)10:2063-2071.

The Age-Related Eye Disease Study 2 Research Group: Visual Acuity after Cataract Surgery in Patients with Age-Related Macular Degeneration. Age-Related Eye Disease Study 2 Report No. 5. (Dr. Bressler is a member of the writing committee for this paper and Principal Investigator within the AREDS2 Research Group). Ophthalmology June 2014:121(6) 1229-1236.

Bhavsar AR, Torres K, Bressler NM, Glassman AR, Jampol LM, Kinyoun JL, for the Diabetic Retinopathy Clinical Research Network (Dr. Bressler served as Vice Chair of the DRCR.net during this project). One Year Results Evaluation Following Short Term Use of Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy. JAMA Ophthalmol. July 2014;132(7):889-890.

The Diabetic Retinopathy Clinical Research Network. Reproducibility of Spectral Domain Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Time Domain Metrics in Diabetic Macular Edema. (Writing Committee: Bressler SB, Edwards AR, Chalam KV, Bressler NM, Glassman AR, et al.) JAMA Ophthalmol 2014; 132(9):1113-1122.

Chaikitmongkol V, Bressler NM, Bressler SB. Early detection of choroidal neovascularization facilitated with a home monitoring program in age-related macular degeneration. Retin Cases Brief Rep. 2015;9(1):33-7.

Tanaka E, Chaikitmongkol V, Bressler SB, Bressler NM. Vision-threatening lesions developing with longer-term follow-up after treatment of neovascular age-related macular degeneration. Ophthalmology. 2015;122(1):153-61.

Elman M, Ayala A, Bressler N, Browning D, Flaxel C, et al for the Diabetic Retinopathy Clinical Research Network. Intravitreal Ranibizumab for Diabetic Macular Edema with Prompt versus Deferred Laser Treatment: 5-Year Randomized Trial Results (Dr. Bressler served as Vice Chair for the DRCR.net during this trial). Ophthalmology 2015; 122(2):375-81.

The Diabetic Retinopathy Clinical Research Network. Reproducibility of Optovue RTVue Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Zeiss Stratus Metrics in Diabetic Macular Edema. (Writing Committee: Bressler SB, Edwards AR, Andreoli CM, Edwards PA, Glassman AR) Trans Vis Sci Tech Jan/Feb 2015; 4(1)5.

Elman M, Ayala A, Bressler N, Browning D, Flaxel C, et al for the Diabetic Retinopathy Clinical Research Network. Topical Nepafenec in Eyes with Non-Central Diabetic Macular Edema. (Dr. Bressler served as a Vice Chair for the DRCR.net during this trial). Retina, Feb 2015; 35(5): 944-956.

Bressler S, Melia M, Glassman A, Almukhtar T, Jampol L, et al for the Diabetic Retinopathy Clinical Research Network. Ranibizumab Plus Prompt or Deferred Laser for Diabetic Macular Edema in Eyes with Vitrectomy Prior to Anti-Vascular Endothelial Growth Factor Therapy. Retina, May 2015. DOI: 10.1097/IAE.0000000000000617.

The Diabetic Retinopathy Clinical Research Network. Repeated Intravitreous Ranibizumab Injections for Diabetic Macular Edema and the Risk of Sustained IOP Elevation or Ocular Hypotensive Treatment. (Writing Committee: Bressler SB, Almukhtar T, Bhorade A, Bressler NM, Glassman AR, et al). JAMA Ophthalmol. 2015;133(5):589-597.

Thomas M, Wolfson Y, Zayit-Soudry S, Bressler S, Bressler N: Qualifying to Use a Home Device to Monitor for Detection of Neovascular Age-related Macular Degeneration. In press JAMA Ophthmol 2015.

Mitchell P, Massin P, Bressler SB, Coon C, Petrillo J, et al. Three-Year Patient-Reported Visual Function Outcomes in Diabetic Macular Edema Managed with Ranibizumab: The RESTORE Extension Study. In press Curr Med Res Opin, 2015.

Bressler SB, Ayala A, Bressler NM, Melia M, Qin H, et al. for the Diabetic Retinopathy Clinical Research Network. An Exploratory Analysis of Persistent Macular Thickening Following Intravitreous Ranibizumab for Center-involved Diabetic Macular Edema with Vision Impairment. Submitted to JAMA Ophthalmol 2015.

Bressler SB, Bressler NM, Fine SL et al: Natural course of choroidal neovascular membranes within the foveal avascular zone in senile macular degeneration. Am JOphthalmol 1982;93:157‑163.

Fine SL, Bressler NM, Bressler SB, Murphy RP: Macular degeneration update 1983. Trans Pac Coast Oto‑Ophthalmol Soc 1982;63: 35‑40.

Fine SL, Bressler NM, Bressler SB, Murphy RP: Macular degeneration update 1983. Trans Pac Coast Oto‑Ophthalmol Soc 1982;63: 35‑40

Bressler SB, Bressler NM, Fine SL et al: Subfoveal neovascular membranes in senile macular degeneration: Relationship between membrane size and visual prognosis. Retina 1983;3:7‑11.

Weiss JS, Bressler SB, Jacobs EF Jr et al: Maxillary amelioblastoma with orbital invasion. Ophthalmology 1985;92:710‑713.

Bressler NM, Bressler SB, Gragoudas EG: Clinical characteristics of choroidal neovascular membranes. Arch Ophthalmol 1987;105:209‑213.

Bressler NM, Bressler SB, Fine SL: Age‑related macular degeneration. Surv Ophthalmol 1988;32:375‑413.

Bressler SB, Bressler NM, Seddon JS, et al: Interobserver and intraobserver reliability in the clinical classification of drusen. Retina 1988;8:102‑108.

Bressler NM, Bressler SB, Seddon JS et al: Drusen characteristics in patients with exudative versus non‑exudative age‑related macular degeneration. Retina 1988;8:109‑114.

Bressler NM, Frost L, Bressler SB, Fine SL: Natural course of poorly defined choroidal neovascularization in macular degeneration. Arch Ophthalmol, 1988;106:1537‑1542.

Bressler NM, Bressler SB, West S et al: The grading and prevalence of macular degeneration in Chesapeake Bay watermen. Arch Ophthalmol, 1989;107:847‑852.

Sunness JS, Massof RW, Bressler NM, Bressler SB: Diminished foveal sensitivity may predict the development of advanced age‑related macular degeneration. Ophthalmology 1989;96:375‑381.

West S, Bressler NM, Bressler SB et al: Exposure to sunlight and other risk factors associated with age‑related macular degeneration. Arch Ophthalmol 1989;107:875‑879.

Sunness JS, Massof RW, Bressler NM, Bressler SB: S cone pathway sensitivity in eyes with high risk and low risk drusen characteristics. Applied Optics 1989;28:1158‑1164.

Macular Photocoagulation Study Group: Persistent and recurrent neovascularization after krypton laser photocoagulation for neovascular lesions of ocular histoplasmosis. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1989;107:344‑352.

Chamberlin JA, Bressler NM, Bressler SB, et al: The use of fundus photographs and fluorescein angiograms in the identification and treatment of choroidal neovascularization in the Macular Photocoagulation Study. Ophthalmology 1989;1526‑1534.

Maguire MG, Folk JC, Singerman LJ, Schachat AP, Blackhurst DW, Chamberlin JA, Bressler NM, Fine SL, Hawkins BS, Elman MJ, Macular Photocoagulation Study Group: Response to: Partial ablation of neovascular membranes involving the fovea. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1989;107:955-956.

Macular Photocoagulation Study Group: Krypton laser photocoagulation for neovascular lesions of age‑related macular degeneration: results of a randomized clinical trial. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1990;108:816‑824.

Macular Photocoagulation Study Group: Krypton laser photocoagulation for idiopathic neovascular lesions: results of a randomized clinical trial. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1990;108:832‑837.

Macular Photocoagulation Study Group: Persistent and recurrent neovascularization after krypton laser photocoagulation for neovascular lesions of age‑related macular degeneration. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1990;108:825‑831.

Bressler SB, Maguire MG, Bressler NM et al: Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. Arch Ophthalmol 1990;108:1442‑1447.

Taylor HR, Munoz B, West S, Bressler NM, Rosenthal FS, Bressler SB: Visible light and risk of age-related macular degeneration. Tr Am Ophth Soc 1990; 88:163-178.

Bressler NM, Bressler SB, Alexander J, et al: Loculated fluid: A previously undescribed angiographic finding in macular degeneration. Arch Ophthalmol 1991;109:211-215. (Although listed as second author, the concept, execution, analysis, and manuscript preparation of this project was equally shared by the first and second author).

Kwiterovich KA, Fine SL, Maguire MG, Bressler NM, Bressler SB, Murphy RP: Fluorescein angiography: frequency of adverse reactions. Ophthalmology 1991;98:1139-1142.

Macular Photocoagulation Study Group: Argon laser photocoagulation for neovascular maculopathy after five years. Results from randomized clinical trials. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1991;109:1109-1114.

Macular Photocoagulation Study Group: Laser photocoagulation of subfoveal neovascular lesions in age-related macular degeneration: Results of a randomized clinical trial. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1991;109:1219-1230.

Macular Photocoagulation Study Group: Laser photocoagulation of subfoveal recurrent neovascular lesions in age-related macular degeneration: Results of a randomized clinical trial. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1991;109:1232-1241.

Bressler NM, Alexander JA, Bressler SB et al: Subfoveal neovascular lesions in age-related macular degeneration: Guidelines for evaluation and treatment in the Macular Photocoagulation Study. Arch Ophthalmol 1991;109:1242-1257.

Folk JC, Blackhurst DW, Alexander J, Elman MJ, Phillips DA, Macular Photocoagulation Study Group: Pretreatment fundus characteristics as predictors of recurrent choroidal neovascularization. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1991;109:1193-1194.

Taylor HR, West S, Munoz B, Rosenthal FS, Bressler SB, Bressler NB: The long-term effects of visible light on the eye. Arch Ophthalmol 1992;110:99-106.

Bressler SB, Silva JC, Bressler NM, Alexander JA, Green WR: Clinicopathologic correlation of occult choroidal neovascularization in age-related macular degeneration. Arch Ophthalmol, 1992;110:827-832.

Lim JI, Bressler NM, Marsh MJ, Bressler SB: Laser treatment of choroidal neovascularization in patients with angioid streaks. Am J Ophthalmol 1993 Oct;116:414-423.

Bressler NM, Alexander J, Hawkins BS, Maguire MG, Fine SL, Macular Photocoagulation Study Group: Response to: Subfoveal neovascular lesions in age-related macular degeneration. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1993;111:901.

Burgess DB, Hawkins BS, Jefferys J, Bressler NM, Bressler SB: Macular Photocoagulation Study Group: Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Arch Ophthalmol 1993;111:1189-1199.

Macular Photocoagulation Study Group: Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration: Updated findings from two clinical trials. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1993;111:1200-1209.

Dastgheib K, Bressler SB, Green WR: Clinicopathologic correlation of laser lesion expansion following treatment of choroidal neovascularization. Retina 1993;13:345-352.

West S, Vitale S, Hallfrisch J, Munoz B, Muller D, Bressler SB, Bressler NM: Are antioxidants or supplements protective for age-related macular degeneration. Arch Ophthalmol 1994;112:222-227.

Bressler NM, Silva J, Bressler SB, Fine SL, Green WR: Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration. Retina 1994;14:130-142.

Macular Photocoagulation Study Group: Laser photocoagulation of juxtafoveal choroidal neovascularization: Five-year results from randomized clinical trials. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1994;111:500-509.

Maguire MG, Fine SL, Folk JC, Bressler NM, et al. for the Macular Photocoagulation Study Group: Visual outcome after laser photocoagulation for subfoveal choroidal neovascularization secondary to age-related macular degeneration: The influence of initial lesion size and initial visual acuity. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1994;112:480-488

Macular Photocoagulation Study Group: Persistent and recurrent choroidal neovascularization after laser photocoagulation for subfoveal choroidal neovascularization of age-related macular degeneration. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1994;112:489-499

Pieramici DJ, Bressler NM, Bressler SB, Schachat AP: Choroidal neovascularization in black patients. Arch Ophthalmol 1994;112:1043-1046.

Bressler SB, Jefferys JL, Bressler NM, Alexander J, et al, for the Macular Photocoagulation Study Group: Evaluation of argon green versus krypton red laser for photocoagulation of subfoveal choroidal neovascularization in the Macular Photocoagulation Study. Arch Ophthalmol 1994;112:1176-1184.

Sykes SO, Bressler NM, Maguire MG, Schachat AP, Bressler SB: Detecting recurrent choroidal neovascularization: Comparison of clinical examination with and without fluorescein angiography. Arch Ophthalmol 1994;112:1561-1566.

Edwards MG, Schachat AP, Bressler SB, Bressler NM: Outcome of cataract surgery performed to permit diagnosis, determine eligibility for laser therapy, or perform laser therapy of retinal disorders. Am J Ophthalmol, 1994;118(4):440-444.

Macular Photocoagulation Study Group: Laser photocoagulation for neovascular lesions nasal to the fovea associated with ocular histoplasmosis or idiopathic causes. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1995;113:56-61.

Macular Photocoagulation Study Group: The influence of treatment coverage on the visual acuity of eyes treated with krypton laser for juxtafoveal choroidal neovascularization. (Dr. Bressler is a member of the MPS Group). Arch Ophthalmol 1995;113:190-194.

Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, et al: An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International AMD Epidemiological Study Group. Surv Ophthalmol 1995;39:5:367-374.

Bressler NM and Bressler SB: Preventive Ophthalmology: Age-related macular degeneration. Ophthalmology 1995;102:1206-1211.

Dyer DS, Brant AM, Schachat AP, Bressler SB, Bressler NM: Angiographic features and outcome of questionable recurrent choroidal neovascularization. Am J Ophthalmol 1995;120(4):497-505.

Duncan DD, Schneider W, West KJ, Kirkpatrick SJ, West SK, and the Salisbury Eye Evaluation Project Team: The development of personal dosimeters for use in the visible and ultraviolet wavelength regions. (Dr. Bressler is a member of The SEE Project Team). Photochem Photbiol 1995;62:94-100.

Bressler NM, Marsh MJ, Maguire MG, Alexander J, Phillips DA, Javornik NB, Heiner CJ, Bressler SB et al for the MPS Group: Occult choroidal neovascularization: Influence on visual outcome in patients with age-related macular degeneration. Arch Ophthalmol 1996;114:400-412.

Wilkinson CP, Hawkins BS, Javornik NB, Newhouse MM, Bressler NM, Bressler SB et al for the MPS Group: Five-year follow-up of fellow eyes of individuals with ocular histoplasmosis and unilateral extrafoveal or juxtafoveal choroidal neovascularization. Arch Ophthalmol 1996;114:677-688.

Kiri A, Dyer DS, Bressler NM, Bressler SB, Schachat AP: Detection of diabetic macular edema: Nidek 3Dx stereo photography compared with fundus biomicroscopy. Am J Ophthalmol 1996;122:5:654-662.

Bressler NM, Maguire MG, Murphy PL, Alexander J, Margherio R, Schachat AS, Fine SL, Stevens TS, Bressler SB: Macular scatter ('grid') laser treatment of poorly demarcated subfoveal choroidal neovascularization in age-related macular degeneration: Results of a randomized pilot trial. Arch Ophthalmol 1996;114:1456-1464.

Stevens TS, Bressler NM, Maguire MG, Bressler SB, Fine SL, et al: Occult choroidal neovascularization in age-related macular degeneration: A natural history study of morphologic changes. Arch Ophthalmol 1997;115:345-350.

West SK, Munoz B, Rubin GS, Schein O, Bandeen-Roche K, Zeger S, German P, Fried L, and the SEE Project Team: Function and vision impairment in a population-based study of older adults. (Dr. Bressler is a member of The SEE Project Team). Invest Ophthalmol Vis Sci 1997;38:72-82.

Duncan DD, Munoz B, Bandeen-Roche K, West SK, and the Salisbury Eye Evaluation Project Team: Visible and ultraviolet-B ocular-ambient exposure ratios for a general population. (Dr. Bressler is a member of The SEE Project Team). Invest Ophthalmol Vis Sci 1997;38:5:1003-1011.

West S, Rubin G, Munoz B, Abraham D, Fried LP, and Salisbury Eye Evaluation Project Team: Assessing functional status: Correlation between performance on tasks conducted in a clinic setting and performance on the same task conducted at home. (Dr. Bressler is a member of The SEE Project Team). J Gerontol 1997;52a:4:M209-M217.

Pharmacological Therapy for Macular Degeneration Study Group: Interferon Alfa-2a is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration: results of a prospective randomized placebo-controlled clinical trial. (Dr. Bressler is a member of the Pharmacological Therapy for Macular Degeneration Study Group). Arch Ophthalmol 1997;115:865-72.

Rubin GS, West SK, Munoz B, Bandeen-Roche K, et al., for the SEE Project Team: A comprehensive assessment of visual impairment in an older American population: SEE Study. (Dr. Bressler is a member of The SEE Project Team). Invest Ophthalmol Vis Sci 1997;38:557-568.

Maguire MG, Bressler SB, Bressler NM, Alexander J, et al for the Macular Photocoagulation Study Group: Risk factors for choroidal neovascularization in the second eye of patients with juxtafoveal or subfoveal choroidal neovascularization secondary to age-related macular degeneration. Arch Ophthalmol 1997;15:741-747.

Duncan DD, Munoz B, Bandeen-Roche K, West SK, and Salisbury Eye valuation Project Team: Assessment of ocular exposure to ultraviolet-B for population studies. (Dr. Bressler is a member of The SEE Project Team). Photochem and Photobiol 1997;66[5]:701-709.

Grossniklaus HE, Green WR for the Submacular Surgery Trials Research Group: Histopathologic and ultrastructural findings of surgically excised choroidal neovascularization. Arch Ophthalmol 1998;116:745-749.

Rosberger DF, Schachat AP, Bressler SB, Bressler NM: Availability of color fundus photographs from previous visit affects practice patterns for patients with diabetes mellitus. Arch Ophthalmol 1998;116:1607-1610.

Weisz JM, Bressler NM, Bressler SB, Schachat AS: Ketorolac treatment of pseudophakic cystoid macular edema identified more than 24 months after cataract surgery. Ophthalmology 1999;106:1656-1659.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group: Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of two randomized clinical trials -- TAP Report No. 1. (Dr. Bressler is a member of the Writing Committee for this paper). Arch Ophthalmol 1999; 117;1329-1345.

Age-Related Eye Disease Study Research Group: The Age-Related Eye Disease Study (AREDS): Design implications. AREDS Report No. 1. (Dr. Bressler is a member of this manuscript's editorial committee). Controlled Clinical Trials 1999;20:573-600.

Age-Related Eye Disease Study Research Group: The Age-Related Eye Disease Study: A clinical trial of zinc and antioxidants -- AREDS Report No. 2. (Dr. Bressler is a member of this manuscript's editorial committee). J Nutr 2000;130:1516S-1519S.

Age-Related Eye Disease Study Research Group: Risk factors associated with age-related macular degeneration: A case-control study in the Age-Related Eye Disease Study: AREDS Report No. 3. Writing team: Anand R, Bressler SB, Davis MD, Ferris FL, Klein R, Lindblad AS, Milton RC, Sperduto RD. Ophthalmology 2000;107:2224-2232.

Bressler NM, Bressler SB: Photodynamic therapy with Verteporfin (Visudyne): Impact on Ophthalmology and Visual Sciences. Investigative Ophthalmology and Visual Sciences 2000;41:3;624-628.

Munoz B, West SK, Rubin GS, Schein OD, Quigley HQ, Bressler SB, Fried L, Bandeen-Roche, K, and SEE Study Team: Causes of blindness and visual impairment in a population of older Americans: The SEE Study. Arch Ophthalmol 2000;118:819-825.

Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group: Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with Verteporfin: Two-year results of two randomized clinical trials -- TAP Report No. 2. (Dr. S. Bressler was a member of the Writing Committee for this paper). Arch Ophthalmol 2000;119:198-207.

Bressler NM, Bressler SB, Cotch MF, Hawkins BS, Marsh MJ, et al for The Submacular Surgery Trials Pilot Study Investigators: Submacular Surgery Trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration. I. Ophthalmic outcomes. SST Pilot Study Report No. 1. (Dr. Bressler was a member of this manuscript's writing team). Am J Ophthalmol 2000;130:4:387-407.

Submacular Surgery Trials Pilot Study Investigators: Submacular Surgery Trials randomized pilot trial of laser versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration. II. Quality of life outcomes. SST Pilot Study Report No. 2. (Dr. Bressler is a member of this manuscript's writing team). Am J Ophthalmol 2000;130:4:408-418.

Age-Related Eye Disease Study Research Group: The Age-Related Eye Disease Study (AREDS) system for classifying cataracts from photographs: AREDS Report No. 4. (Dr. S. Bressler is a member of this manuscript's editorial committee). Am J Ophthalmol 2001;131:167-175.

Age-Related Eye Disease Study Research Group: Risk factors associated with age-related nuclear and cortical cataract: A case control study in the Age-Related Eye Disease Study. AREDS Report No. 5. (Dr. S. Bressler is a member of the Editorial Committee for this paper). Ophthalmology 2001;108:1400-1408.

Age-Related Eye Disease Study Research Group: The AREDS system for classifying age-related macular degeneration from photographs. AREDS Report No. 6. (Dr. S. Bressler was a member of the Writing Committee for this report). Am J Ophthalmol 2001;132:668-681.

Age-Related Eye Disease Study Research Group: A randomized, placebo-controlled clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS Report No. 8. (Dr. Bressler is a member of the writing team of this paper). Arch Ophthalmol 2001;119:1417-1436.

The Age-Related Eye Disease Study Research Group: A randomized, placebo-controlled clinical trial of high-dose antioxidant supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss. AREDS Report No. 9. (Dr. Bressler is a member of the writing team of this paper). Arch Ophthalmol 2001;119:1439-1452.

Verteporfin in Photodynamic Therapy (VIP) Study Group: Photodynamic therapy of subfoveal choroidal neovascularization and pathologic myopia with Verteporfin: One-year results of a randomized clinical trial -- VIP Report No. 1. (Dr. S. Bressler was a member of this writing team). Ophthalmology 2001;108:841-852.

Verteporfin In Photodynamic Therapy (VIP) Study Group: Verteporfin Therapy of Subfoveal Choroidal Neovascularization in Age-Related Macular Degeneration: Two-Year Results of a Randomized Clinical Trial Including Lesions with Occult with No Classic Choroidal Neovascularization -- VIP Report No. 2. (Dr. S. Bressler is a critical member of this writing team). Am J Ophthalmol 2001;131:5:541-560.

Verteporfin Roundtable 2000 and 2001 Participants, Treatment of Age-related macular degeneration with Photodynamic therapy (TAP) Study Group Principal Investigators, and Verteporfin in Photodynamic therapy (VIP) Study Group Principal Investigators: Guidelines for using Verteporfin (Visudyne™) in photodynamic therapy to treat choroidal neovascularization due to age-related macular degeneration and other causes. (Dr. S. Bressler is a member of the Verteporfin Roundtable 2000 and 2001 and a TAP and VIP Principal Investigator). Retina 2002;22:6-18.

The Age-Related Eye Disease Study Research Group: The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the Age-Related Eye Disease Study: AREDS Report No. 7. (Dr. S. Bressler is a member of the editorial committee for this paper). J. Nutr. 2002;132:697-702.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group: Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: Three-year results of an open-label extension of 2 randomized clinical trials -- TAP Report No. 5. (Dr. S. Bressler is a member of the writing team for this publication). Arch Ophthalmol 2002;120:1307-1314.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group: Verteporfin Visudyne therapy of additional choroidal neovascularization in age-related macular degeneration: Additional information regarding baseline lesion composition's impact on vision outcomes -- TAP Report No. 3. (Dr. S. Bressler is a member of the writing committee for this manuscript). Arch Ophthalmol 2002;120:1443-1454.

Rubin GS, Bressler NM and the Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group: Effects of verteporfin therapy on contrast sensitivity: Results from the treatment of age-related macular degeneration with photodynamic therapy (TAP) investigation-- TAP Report No. 4. (Dr. S. Bressler is a member of the TAP Group). Retina 2002;22:536-544.

Saperstein DA, Rosenfeld PJ, Bressler NM, et al. Photodynamic therapy of subfoveal choroidal neovascularization with verteporfin in the ocular histoplasmosis syndrome: one-year results of an uncontrolled, prospective case series. (Dr. S. Bressler is PI of the Reading Center for this study and a member of the study group). Ophthalmol 2002;109:1499-1505.

Clemens TE, Chew EY, Bressler SB, McBee W for the AREDS Research Group: National Eye Institute Visual Function Questionnaire in the Age-Related Eye Disease Study (AREDS). Report No. 10. Arch Ophthalmol 2003;121:211-217.

Ladd BS, Solomon SS, Bressler NM, Bressler SB: Photodynamic therapy with verteporfin for choroidal neovascularization in patients with diabetic retinopathy. Am J Ophthalmol 2003;132:5:659-667.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group and Verteporfin in Photodynamic Therapy (VIP) Study Groups: Effect of baseline lesion size, visual acuity, and lesion composition on visual acuity change with and without Verteporfin therapy for choroidal neovascularization secondary to age-related macular degeneration: TAP and VIP Report No. 1. (Dr. S. Bressler is a member of the writing team for this publication). Am J Ophthalmol 2003;136:407-418.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group and Verteporfin in Photodynamic Therapy (VIP) Study Groups: Photodynamic therapy of subfoveal choroidal neovascularization with verteporfin: Fluorescein angiographic guidelines for evaluation and treatment. TAP and VIP Report No. 2. (Dr. Bressler chaired the Writing Committee for this manuscript). Arch Ophthalmol 2003;121:1253-1268.

Mimouni KF, Bressler SB, Bressler NM: Photodynamic therapy for Subfoveal choroidal neovascularization in children. Am J Ophthalmol 2003; 135(6):900-2.

Verteporfin in Photodynamic Therapy (VIP) Study Group: Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: Two-year results of a randomized clinical trial -- VIP Report No. 3. (Dr. S. Bressler was a member of the Writing Committee for this report). Ophthalmology 2003;110(4): 667-73.

DiLoreto DA, Bressler, NM, Bressler SB, Schachat AP: Best and final visual acuity in ophthalmologic research. Arch Ophthalmol 2003;121:1586-1590.

Age-Related Eye Disease Study Research Group: Potential public health impact of AREDS Results: AREDS report No. 11. (Dr. Bressler is a member of the writing team of this paper). Arch Ophthalmol 2003;121:1621-1624.

Japanese Age-Related Macular Degeneration Trial (JAT) Study Group: Japanese Age-related macular degeneration Trial (JAT): One-year results of photodynamic therapy with verteporfin in Japanese patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. (Dr. S. Bressler is a member of the writing team for this publication). Am J Ophthalmol 2003;136:1049-1061.

The Submacular Surgery Trials Research Group: Responsiveness of the National Eye Institute Visual Function Questionnaire to Changes in Visual Acuity: Findings in patients with subfoveal choroidal neovascularization: SST Report No. 1(Dr. S. Bressler is a member of the SST Research Group). Arch Ophthalmol 2003;121: 531 – 539.

Childs AL and the Submacular Surgery Trials Patient-Centered Outcomes Subcommittee for the Submacular Surgery Trials Pilot Study Investigators: Responsiveness of the SF-36 Health Survey to changes in visual acuity among patients with subfoveal choroidal neovascularization. (Dr. S. Bressler is an SST Pilot Study Investigator). Am J Ophthalmol 2004;173:373 - 375.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) and Verteporfin in Photodynamic Therapy (VIP) Study Groups: Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: Meta-analysis of 2-year safety results in three randomized clinical trials: TAP and VIP Report No. 4. (Dr. Bressler is a member of the writing team of this paper). Retina 2004;24:1-12.

Do DV, Bressler NM, Bressler SB: Large Submacular hemorrhages after verteporfin therapy. Am J Ophthalmol 2004;137: 558-560.

Brown JC, Solomon SD, Bressler SB, Schachat AP, DiBernardo C, and Bressler NM: Detection of diabetic foveal edema: Contact lens biomicroscopy compared with optical coherence tomography. Arch Ophthalmol 2004;122;330-335.

Bressler SB, Pieramici DJ, Koester MS, Bressler NM for the Treatment of Age-related Macular Degeneration with Photodynamic Therapy (TAP) Study Group: Natural history of minimally classic subfoveal choroidal neovascular lesions in the treatment of age-related macular degeneration with photodynamic therapy (TAP) investigation: Outcomes potentially relevant to management. TAP Report No. 6. (Dr. S. Bressler chaired this writing committee). Arch Ophthalmol 2004;122;325-329.

Age-Related Eye Disease Study Research Group: Mortality in the Age-Related Eye Disease Study: Associations with ocular disorders and an intervention of high-dose antioxidants and zinc. AREDS Report No. 13. (Dr. S. Bressler is a member of the writing team of this report). Arch Ophthalmol 2004;122;716-726.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) and Verteporfin in Photodynamic Therapy (VIP) Study Groups: Acute severe visual acuity decrease after photodynamic therapy with verteporfin: Case reports from randomized clinical trials. TAP and VIP Report No. 3. (Dr. Bressler is a member of the writing team of this paper.) Am J Ophthalmol 2004;137;683-696.

Blair MP, Apte R, Bressler NM, Miskala P, Schachat AP, Bressler SB, Goldberg MF: A retrospective case series of juxtafoveal choroidal neovascularization treated with photodynamic therapy with Verteporfin. Retina 2004;24;501-506.

Verteporfin in AMD (VAM) Study Group. Verteporfin therapy in age-related macular degeneration (VAM): an open-label multicenter photodynamic therapy study of 4435 patients. (Dr. S. Bressler is a member of the VAM Study Group). Retina 2004;24:512-520.

The Submacular Surgery Trials Research Group: Health- and vision-related quality of life among patients with choroidal neovascularization secondary to age-related macular degeneration at enrollment in randomized trials of Submacular surgery: SST Report No. 4. (Dr. S. Bressler is a member of the SST Research Group). Am J Ophthalmol 2004;138:91-108.

The Submacular Surgery Trials Research Group: Surgical removal versus observation for subfoveal choroidal neovascularization, either associated with the ocular histoplasmosis syndrome or idiopathic. I. Ophthalmic findings from a randomized clinical trial: Submacular Surgery Trials (SST) Group H Trial. SST Report No. 9. (Dr. S Bressler is a member of the writing team of this report). Arch Ophthalmol 2004;122:1597-1611.

The Submacular Surgery Trials Research Group: Surgical removal vs observation for subfoveal choroidal neovascularization, either associated with the ocular histoplasmosis syndrome or idiopathic. II. Quality-of-life findings from a randomized clinical trial: SST Group H Trial: SST Report No. 10. (Dr. S Bressler is a member of the SST Research Group). Arch Ophthalmol, 2004;122:1616-1628.

The Submacular Surgery Trials (SST) Research Group: Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: Ophthalmic findings: SST Report No. 11. (Dr. S Bressler is a member of the writing team of this report). Ophthalmol 2004;111:1967-1980.

The Submacular Surgery Trials (SST) Research Group: Surgery for subfoveal choroidal neovascularization in Age-Related Macular Degeneration: Quality-of-Life findings: SST Report No. 12. (Dr. S Bressler is a member of the SST Research Group). Ophthalmol 2004;111:1981-1992.

The Submacular Surgery Trials (SST) Research Group: Surgery for hemorrhagic choroidal neovascular lesions of Age-Related Macular Degeneration: Ophthalmic findings: SST Report No. 13. (Dr. S Bressler is a member of the writing team of this report). Ophthalmol 2004;111:1993-2006.

Submacular Surgery Trials (SST) Research Group: Surgery for hemorrhagic choroidal neovascular lesions of Age-Related Macular Degeneration: Quality of Life findings: SST Report No. 14. (Dr. S Bressler is a member of the SST Research Group). Ophthalmol 2004;111:2007-2014.

Sadda S, Pieramici D, Marsh M, Bressler SB, Bressler NB, et al: Changes in Lesion Size After Submacular Surgery for Subfoveal Neovascularization: Pilot Study. Retina 2004;24:888-899.

Rosenfeld PJ, Saperstein DA, Bressler NM, et al for the VOHS Study Group (Dr. S Bressler is a member of the VOHS Study Group) Photodynamic therapy of subfoveal choroidal neovascularization with verteporfin in the ocular histoplasmosis syndrome: two-year results of an uncontrolled, open-label clinical study. Ophthalmology 2004;111:1725-1733.

Submacular Surgery Trials (SST) Research Group: Patients' perceptions of the value of current vision: Findings from the Submacular Surgery Trials (SST) Vision Preference Value Scale (SST-VPVS): SST Report No. 6. (Dr. Bressler is a member of the SST Research Group.) Arch Ophthalmol 2004; 122:1856-1867.

The Age-Related Eye Disease Study Research Group: Impact of antioxidants, zinc, and copper on cognition in the elderly. A randomized, controlled clinical trial. AREDS Report No. 12. (Dr. S Bressler is a member of the AREDS Research Group). Neurology 2004;63:1705-1707.

The Age-Related Eye Disease Study Research Group: Responsiveness of the NEI-VFQ to progression to advanced AMD, vision loss, lens opacity, and cataract surgery. (Dr. S. Bressler is a member of the editorial committee on this paper). AREDS report No. 14. Ophthalmol 2004; 111:2007-2014.

Submacular Surgery Trials (SST) Research Group: Health and vision-related quality of lie among patients with ocular histoplasmosis or idiopathic choroidal neovascularization at time of enrollment in a randomized trial of Submacular surgery. SST Report No. 5. (Dr. Bressler is a member of the SST Research Group.) Arch Ophthalmol 2005;123:78-88.

The Age-Related Eye Disease Study Research Group: Risk factors for the incidence of advanced age-related macular degeneration in the Age-Related Eye Disease Study (AREDS). AREDS Report No. 19. (Dr. S. Bressler is a member of the editorial committee on this paper). Ophthalmology 2005;112:533-539.

Visudyne in Minimally Classic CNV (VIM) Study Group: Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: Two-year results of a randomized clinical trial. (Dr. S. Bressler is a member of the writing team of this paper). Arch Ophthalmol 2005;123:448-457.

Freeman EE, Munoz B, Bressler SB, West SK: Hormone replacement therapy, reproductive factors, and age-related macular degeneration: The Salisbury Eye Evaluation Project. Ophthalmic Epidemiology 2005;12(1):37-46.

Gass JDM, Bressler SB, Akduman L, Olk J, Caskey PJ, Zimmerman LE: Bilateral idiopathic multifocal retinal pigment epithelium detachments in otherwise healthy middle-aged adults. A clinicopathologic study. Retina 2005;25:304-310.

The Submacular Surgery Trials Research Group: Guidelines for interpreting retinal photographs and coding findings in the Submacular Surgery Trials (SST). SST Report No. 8. (Dr. S. Bressler served as co-chair of this writing committee). Retina 2005;25:253-268.

The Age-Related Eye Disease Study Research Group: The Age-Related Eye Disease Study Severity Scale for age-related macular degeneration. AREDS Report No. 17. (Dr. S. Bressler is a member of the writing team of this report). Arch Ophthalmol 2005;123:1484-1498.

The Age-Related Eye Disease Study Research Group: A simplified severity scale for age-related macular degeneration. (Dr. S. Bressler is a member of the writing team of this report.) AREDS Report No. 18. Arch Ophthalmol 2005;123:1570-1574.

Moriarty-Craige SE, Adkison J, Lynn M, Gensler G, Bressler S, Jones D, Sternberg P: Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration. Am J Ophthalmol 2005;140:1020-1026.

The Submacular Surgery Trials Research Group: Histopathological and ultrastructural features of surgically-excised subfoveal choroidal neovascular lesions: SST Report No. 7. (Dr. S. Bressler is a member of the writing team of this report). Arch Ophthalmol 2005;123:914-921.

Preferential Hyperacuity Perimeter (PHP) Research Group: Preferential hyperacuity perimeter (PreView PHP) for detecting choroidal neovascularization Study. (Dr. S. Bressler is a member of the writing team of this report). Ophthalmology 2005;112:1758-1765.

Preferential Hyperacuity Perimeter (PHP) Research Group: Results of a multicenter clinical trial to evaluate the preferential hyperacuity perimeter for detection of age- related macular degeneration. (Dr. S. Bressler is a member of the PHP Research Group). Retina 2005; 25:296-303.

The Submacular Surgery Trials Research Group: Effect of order of administration of health-related quality of life interview instruments on responses - Submacular Surgery Trials Report No. 3. (Dr. S. Bressler is a member of the SST Research Group). Qual Life Res 2005;14:493-500.

Lai MM, Bressler SB, Haller JA: Spontaneous resolution of macular microhole. Am J Ophthalmol 2006;141:210-212.

The Submacular Surgery Trials Research Group: Comparison of 2-dimensional reconstructions of surgically-excised choroidal neovascularization with fluorescein angiographic features: SST Report No. 15. (Dr. S. Bressler is a member of the writing team of this report). Ophthalmology 2006;113:267-279.

Grossniklaus HE, Wilson DJ, Bressler SB, Bressler NM, Toth CA, Green WR, Miskala P, for the Submacular Surgery Trials Research Group: Clinicopathologic studies of eyes that were obtained postmortem from four patients who were enrolled in the Submacular Surgery Trials: SST Report No. 16. Am J Ophthalmol 2006;141:93-104.

The Age-Related Eye Disease Study Research Group: Centrum use and progression of age-related cataract in the Age-Related Eye Disease Study (AREDS): A propensity score approach. AREDS Report No 21 (Dr. S. Bressler is a member of the writing team for this paper). Ophthalmology 2006;113:1264-1270.

Do DV, Nguyen QD, Bressler NM, Schachat AP, Solomon SD, Melia M, Bressler SB: Hemoglobin a1c awareness among patients receiving eye care at a tertiary ophthalmic center. Am J Ophthalmol 2006;141(5):951-953.

Complications of Age-Related Macular Degeneration Prevention Trial Research Group: The Complications of Age-Related Macular Degeneration Prevention Trial: Laser treatment in patients with bilateral large drusen. (Dr. S. Brssler is a member of the CAPT Research Group). Ophthalmol 2006;113:1974-1986.

Diabetic Retinopathy Clinical Research Network: Diurnal Variation in Retinal Thickening Measurement by Optical Coherence Tomography in Center-Involved Diabetic Macular Edema. (Dr. S Bressler is a co-investigator in the DRCR.net) Arch Ophthalmol 2006 Dec;124(12):1701-7.

Writing Committee for the VIP Study Group Occult With No Classic Subfoveal Choroidal Neovascular Lesions in Age-Related Macular Degeneration: Clinically relevant natural history information in larger lesions with good vision from the Verteporfin in photodynamic therapy (VIP) Trial -VIP Report No. 4. (Dr. S. Bressler was a member of the Writing Committee for this report). Arch Ophthalmol 2006;124:660-664.

Diabetic Retinopathy Clinical Research Network: Comparison of the modified-ETDRS and mild macular grid laser photocoagulation strategies for diabetic macular edema. (Dr. S Bressler is a co-investigator in the DRCR.net) Arch Ophthalmol 2007;125:469-480.

Moriarty-Craige SE, Khoi-Nguyen HA, Sternberg P, Lynn M, Bressler SB, Gensler G, Jones DP: Effects of long-term zinc supplementation on plasma thiol metabolites and redox status in patients with age-related macular degeneration. Am J Ophthalmol 2007;143:206-211.

Diabetic Retinopathy Clinical Research Network: Relationship between Optical Coherence tomography-measured Central Retinal Thickness and Visual Acuity in Diabetic Macular Edema. (Dr. S. Bressler is a member of the writing team for this report). Ophthalmology 2007;114:525-536.

Age-Related Eye Disease Study Research Group: The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20. (Dr. S. Bressler is a member of the AREDS group). Arch Ophthalmol 2007;125:671-679.

The Submacular Surgery Trials Research Group: Comparison of methods to identify incident cataract in eyes of patients with neovascular maculopathy: SST Report No. 18. (Dr. S. Bressler is a member of the writing team for this report). Ophthalmology 2007;115:127-133.

Submacular Surgery Trials Research Group: Incident Choroidal Neovascularization in Fellow Eyes of Patients with Unilateral Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration: SST Report No. 20. (Dr. S. Bressler is a member of the writing team for this report). Arch Ophthalmol 2007;125(10):1323-1330.

Diabetic Retinopathy Clinical Research Network: Randomized Trial of Peribulbar Triamcinolone Acetonide with and without Focal Photocoagulation for Mild Diabetic Macular Edema: A Pilot Study. (Dr. S Bressler is a co-investigator in the DRCR.net) Ophthalmology 2007 Jun;114(6):1190-6.

Diabetic Retinopathy Clinical Research Network: Reproducibility of Macular Thickness and Volume Using Zeiss Optical Coherence Tomography in Patients with Diabetic Macular Edema. (Dr. S Bressler is a co-investigator in the DRCR.net) Ophthalmology 2007 Aug;114(8):1520-5.

Diabetic Retinopathy Clinical Research Network: A Phase 2 Randomized Clinical Trial of Intravitreal Bevacizumab for Diabetic Macular Edema. (Dr. S Bressler is a co-investigator in the DRCR.net) Ophthalmology 2007;114(10):1860-1867.

Bhavsar AR, Ip MS, Glassman AR; DRCRnet and the SCORE Study Groups: The Risk of Endophthalmitis following Intravitreal Triamcinolone Injection in the DRCRnet and SCORE Clinical Trials. (Dr. S Bressler is a co-investigator in the DRCR.net) Am J Ophthalmol 2007 Sep;144(3):454-456.

Chang MA, Fine HF, Bass E, Bressler SB, Schachat AP, Solomon SD, Bressler NM: Patients' preferences in choosing therapy for retinal vein occlusions. Retina 2007 Jul-Aug;27(6):789-97.

Charkoudian LD, Gower EW, Solomon SD, Schachat AP, Bressler NM, Bressler SB: Vitamin Usage Patterns in the Prevention of Advanced Age-Related Macular Degeneration. Ophthalmology 2008;115(6):1032-1038.

Bressler SB, Munoz B, Solomon SD, West SK, and the Salisbury Eye Evaluation (SEE) Study Team: Racial differences in the Prevalence of age-related macular degeneration: The Salisbury Eye Evaluation (SEE) Project. Arch Ophthalmol 2008;126(2):241-245.

Chang MA, Bressler SB, Munoz B, West S: Racial Differences and other Risk Factors for Incidence and Progression of Age-Related Macular Degeneration: Salisbury Eye Evaluation (SEE) Project. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2395-402.

Davis MD, Bressler SB, Aiello LP, Bressler NB et al and the Diabetic Retinopathy Clinical Research Network Study Group: Comparison of Time-Domain OCT and Fundus Photographic Assessments of Retinal Thickening in eyes with Diabetic Macular Edema. Invest Ophthalmol Vis Sci 2008;49:1745-1752.

Bressler NM, Edwards AR, Antoszyk AN, Beck, RW, Browning DJ, et al on behalf of the Diabetic Retinopathy Clinical Research Network: Retinal thickness on Stratus(tm) optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy. Am J Ophthalmol 2008;145:894-901.

Scott IU, Bressler NM, Bressler SB, Browning DJ, Chan CK et al and the Diabetic Retinopathy Clinical Research Network Study Group. Agreement Between Clinician and Reading Center Gradings of Diabetic Retinopathy Severity Level at Baseline in a Phase 2 Study of Intravitreal Bevacizumab for Diabetic Macular Edema. Retina 2008;28(1):36-404

Klein ML, Ferris FL, Armstrong J, Hwang T, Chew E, Bressler SB, Chandra SR and the AREDS Research Group: Retinal precursors and the development of geographic atrophy in age-related macular degeneration. Ophthalmology 2008;115(6):1026-1031.

Ip MS, Bressler SB, Antoszyk AN, Flaxel CJ.Kim JE, Friedman SM, Qin H and the Diabetic Retinopathy Clinical Research Network: A Randomized Trial Comparing Intravitreal Triamcinolone and Focal/Grid Photocoagulation for Diabetic Macular Edema: Baseline Features. Retina 2008:28(7):919-930.

Diabetic Retinopathy Clinical Research Network. Randomized Trial Comparing Intravitreal Triamcinolone Acetonide and Focal/Grid Photocoagulation for Diabetic Macular Edema. (Dr. S Bressler is a co-investigator in the DRCR.net) Ophthalmology 2008 Sep;115(9):1447-1459.e10

AREDS Report No. 23: The Relationship of Dietary w-3 Long-Chain Polyunsaturated Fatty Acid Intake with Incident Age-Related Macular Degeneration. (Dr. Susan Bressler is a member of the AREDS research group). Arch of Ophthal, 2008:126(9):1274-1279.

Browning DJ, Altaweel MM, Bressler NM, Bressler SB, Scott IU and the Diabetic Retinopathy Clinical Research Network: Diabetic Macular Edema: What is focal and what is diffuse? Am J Ophthalmol 2008 Nov;146(5):649-55.

Solomon SD and Bressler SB: Increased Caucasian Prevalence of Medium and Large Drusen, Focal Pigment Abnormalities, and Advanced Age-related Macular Degeneration Relative to other Ethnic Groups. US Ophthalmic Review 2008:(3)57-61.

Browing DJ, Glassman AR, Aiello LP, Bressler NM, Bressler SB etal and the Diabetic Retinopathy Clinical Research Network: Optical Coherence Tomography measurements and analysis methods in Optical Coherence Tomography studies of diabetic macular edema. Ophthalmology, 2008;115(8)1366-1371.

The Complications of Age-related Macular Degeneration Prevention Trial (CAPT) Research Group: Risk Factors for Choroidal Neovascularization and Geographic Atrophy in the Complications of Age-related Macular Degeneration Prevention Trial. (Dr. Susan Bressler was on the writing committee for this paper). Ophthalmology, 2008;115(9)1474-1479.e6

Chew EY, Sperduto RD, Milton RC, Clemmons TE, Gensler GR, Bressler SB et al : Risk of Advanced Age-related Macular Degeneration Following Cataract Surgery in the Age-Related Eye Disease Study. AREDS Report 25. Ophthalmology 2009:116(2)297-303.

Glassman AR, Beck RW, Browning DJ, Danis RP, Kollman C, for theDiabetic Retinopathy Clinical Research Network Study Group: Comparison of Optical Coherence Tomography Retinal Thickness Measurements in Diabetic Macular Edema with and without Reading Center Manual Grading from a Clinical Trials Perspective. (Dr. Susan Bressler is a Vice Chair of the DRCR.net) IOVS, 2009:20(2)560-566.

Diabetic Retinopathy Clinical Research Network: Three-year Followup of a Randomized Trial Comparing Focal/Grid Photocoagulation and Intravitreal Triamcinolone for Diabetic Macular Edema (Dr. Susan Bressler is a Vice Chair of the DRCR.net). Arch Ophthalmol, 2009: 127(3)245-251.

Sun JK, Aiello LP, Stockman M, et al. For the Diabetic Retinopathy Clinical Research Network: Effects of Dilation on Electronic-ETDRS Visual Acuity (EVA) in Diabetic Patients (Dr. S Bressler is a Vice Chair of the DRCR.net). Invest Ophthalmol Vis Sci. 2009: 50(4)1580-4.

Browning DJ, Apte RS, Bressler SB, et al and the Diabetic Retinopathy Clinical Research Network. Association of the Extent of Diabetic Macular Edema as Assessed by Optical Coherence Tomography with Visual Acuity and Retinal Outcome Variables. Retina, 2009;29(3):300-5.

Chang MA, Bressler SB: Photodynamic Therapy for Chronic Pigment Epithelial Detachment in Central Serous Chorioretinopathy. Canadian Journal of Ophthalmology, 2009;44(2)221-222.

Scott IU, Danis RP, Bressler SB Bressler NM, Browning DJ, et al for the Diabetic Retinopathy Clinical Research Network: Effect of Focal/Grid Photocoagulation on Visual Acuity and Retinal Thickening in Eyes with Non-Center Involved Clinically Significant Diabetic Macular Edema. Retina 2009;29(5)613-617.

Bressler, SB: Introduction: Understanding the Role of Angiogenesis and Antiangiogenic Agents in Age-Related Macular Degeneration for Ophthalmology supplement entitled: Update on Treatment of Neovascular Age-Related Macular Degeneration: Focus on Antiangiogenesis in Clinical Practice. Ophthalmology 2009;116(10):S1-S7.

Solomon SD, Jefferys JL, Hawkins BS, Bressler NM and Bressler SB: Risk Factors for Second Eye Progression to Advanced Age-Related Macular Degeneration: SST Report No. 21 Submacular Surgery Trials Research Group. Retina, 2009;29(8):1080 - 1090.

Dong LM, Stark WJ, Jefferys JL, Al-Hazzaa S, Bressler SB, Solomon SD, Bressler NM: Progression of Age-related Macular Degeneration after Cataract Surgery. Arch Ophthalmol, 2009;127(11):1412-1419.

Scott A and Bressler SB: Retinal Angiomatous Proliferation or Retinal Anastomosis to the Lesion. Nature/Eye 2010 24, 491-436.

Activities & Honors

Honors

  • Dean's List, Smith College, 1975 - 1978
  • First Group Scholar, Smith College, 1976
  • Phi Beta Kappa, 1977
  • Summa Cum Laude, Smith College, 1978
  • Alpha Omega Alpha, Johns Hopkins University School of Medicine, 1981
  • Paul Ehrlich Award in Clinical Investigation, Johns Hopkins University School of Medicine, 1982
  • Citation for Scholastic Achievement, American Medical Women's Association, 1982
  • Heed Fellowship, 1986
  • Heed/Knapp Fellowship, 1987
  • Honor Award, American Academy of Ophthalmology, 1995
  • Faculty Croupier, Monte Carlo Night, Johns Hopkins University School of Medicine, 1995 - 2003
  • M. K. Humphries, Jr. Lecturer, University of Virginia Health Sciences Center, 1996
  • Olga Keith Weiss Scholar, Research to Prevent Blindness, 1998
  • Election to membership, Club Jules Gonin Society, 1998
  • The Paul Sternberg, Jr. Lectureship, Emory University, Atlanta, Georgia, 2002
  • Rosenthal Award, (Macula Society), 2002
  • The Krill Lecture, Chicago Ophthalmological Society, Chicago, Illinois, 2003
  • First Louisville Academy of Ophthalmology Memorial Lectureship, First Louisville Academy of Ophthalmology, Louisville, Kentucky, 2003
  • The Helen Keller Lecture, University of Alabama at Birmingham, 2004
  • Honor Award, The American Society of Retina Specialists, 2004
  • The American Academy of Ophthalmology Senior Achievement Award, 2004
  • Inaugural Recipient: The Julia G. Levy, PhD. Professor of Ophthalmology, Johns Hopkins University School of Medicine, 2004
  • Dr. G.V. Simpson Lectureship in Ophthalmology, Annual Clinical Day in Ophthalmology, London, Ontario, Canada, 2005
  • Twelfth Irving H. Leopold Lecture, Sinai Hospital, New York, 2007
  • Gertrude D. Pyron Award for Lifetime Achievement of Outstanding Research, American Society of Retina Specialists (ASRS), 2008
  • Goodwin M. Breinin, MD Visiting Professorship, New York University Medical Center, New York, NY, 2008
  • Senior Honor Award, The American Society of Retina Specialists, 2008
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