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David Pearse, MD

David Bennett Pearse, MD
Medical Director, Johns Hopkins Bayview Hospital MICU
Professor of Medicine

See Research on Pubmed

Male
Appointment Phone

410-550-5864

Main Location

Johns Hopkins Bayview Medical Center

View All Locations
Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Medical Director, Johns Hopkins Bayview Hospital MICU
  • Professor of Medicine

Expertise

Critical Care Medicine, Pulmonary Disease and Critical Care Medicine, Pulmonary Medicine

Research Interests

Pulmonary endothelial barrier function; Acute lung injury; Pulmonary thromboembolism

Languages

  • English
Additional Resources +
  • Education +

    Training

    • University of Florida College of Medicine (Gainesville FL) (1980)

    Residencies

    • Johns Hopkins University School of Medicine / Medicine (Baltimore MD) (1983)

    Fellowships

    • Johns Hopkins University School of Medicine / Critical Care Medicine (Baltimore MD) (1988)
    • Johns Hopkins University School of Medicine / Pulmonary Medicine (Baltimore MD) (1984)

    Certifications

    • American Board of Internal Medicine / Pulmonary Disease (1986)
    • American Board of Internal Medicine / Internal Medicine (1983)
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Stephens RS, Servinsky LE, Rentsendorj O, Kolb TM, Pfeifer A, and Pearse DB. Protein kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase. Am J Physiol Cell Physiol. 2014; 306(6); C559-C569. PMID: 24401847 [PubMed - in process]

    2. Kolb TM, King LS, Pearse DB. A 32-year-old woman with dyspnea, lung cysts, and previous pneumothoraces. Chest. 2013 Dec 1;144(6):1964-8. doi: 10.1378/chest.13-0902. PMID: 24297131 [PubMed - in process]

    3. Anidi IU, Servinsky LE, Rentsendorj O, Stephens RS, Scott AL, Pearse DB. CD36 and Fyn kinase mediate malaria-induced lung endothelial barrier dysfunction in mice infected with Plasmodium berghei. PLoS One. 2013 Aug 15;8(8):e71010. doi: 10.1371/journal.pone.0071010. eCollection 2013. PMID: 23967147 [PubMed - in process]

    4. D'Alessio FR, Tsushima K, Aggarwal NR, Mock JR, Eto Y, Garibaldi BT, Files DC, Avalos CR, Rodriguez JV, Waickman AT, Reddy SP, Pearse DB, Sidhaye VK, Hassoun PM, Crow MT, King LS. Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase. J Immunol. 2012 Sep 1;189(5):2234-45. doi: 10.4049/jimmunol.1102606. Epub 2012 Jul 27. PMID: 22844117 

    5. Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, Douglas IS, Pearse DB, Tuder RM. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nat Med. 2012 Aug;18(8):1217-23. doi: 10.1038/nm.2843. Epub 2012 Jul 22. PMID: 22820644 

    6. Eberlein M, Reed RM, Permutt S, Chahla MF, Bolukbas S, Nathan SD, Iacono A, Pearse DB, Fessler HE, Shah AS, Orens JB, Brower RG. Parameters of donor-recipient size mismatch and survival after bilateral lung transplantation. J Heart Lung Transplant. 2012 Nov;31(11):1207-1213.e7. doi: 10.1016/j.healun.2011.07.015. Epub 2011 Oct 28. PMID: 22036314

    7. Eberlein M, Permutt S, Chahla MF, Bolukbas S, Nathan SD, Shlobin OA, Shelhamer JH, Reed RM, Pearse DB, Orens JB, Brower RG. Lung size mismatch in bilateral lung transplantation is associated with allograft function and bronchiolitis obliterans syndrome. Chest. 2012 Feb;141(2):451-60. doi: 10.1378/chest.11-0767. Epub 2011 Jul 28. PMID: 21799025 

    8. Rentsendorj O, Damarla M, Aggarwal NR, Choi JY, Johnston L, D'Alessio FR, Crow MT, Pearse DB. Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L161-70. doi: 10.1152/ajplung.00073.2011. Epub 2011 May 13. PMID: 21571906 

    9. Eberlein M, Permutt S, Brown RH, Brooker A, Chahla MF, Bolukbas S, Nathan SD, Pearse DB, Orens JB, Brower RG. Supranormal expiratory airflow after bilateral lung transplantation is associated with improved survival. Am J Respir Crit Care Med. 2011 Jan 1;183(1):79-87. doi: 10.1164/rccm.201004-0593OC. Epub 2010 Aug 6. PMID: 20693376

  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +
  • Events +
  • Contact & Locations +

    Locations

    Johns Hopkins Bayview Medical Center
    5501 Hopkins Bayview Circle
    Asthma and Allergy Center
    Baltimore, MD 21224
    Appointment Phone: 410-550-5864
    Location Map
    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410-955-3467
    Appointment Phone: 410-550-5864
    Location Map
    Johns Hopkins Outpatient Center
    601 N. Caroline Street
    Baltimore, MD 21287
    Appointment Phone: 410-955-3467
    Location Map

    Department/Division

    • Medicine - Pulmonary and Critical Care Medicine

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