Dr. Lederman’s current research laboratory and clinical research focuses on better understanding and treating patients with ataxia-telangiectasia, a devastating neurological disorder for which there is no cure.
Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia
Clinical Trial Keywords:
Immunoglobulin, Gamma globulin, Ataxia- Telangiectasia
McGrath-Morrow S, Lefton-Greif M, Rosquist K, Crawford T, Kelly A, Zeitlin P, Carson K , Lederman HM. "Pulmonary function in adolescents with ataxia-telangiectasia." Pediatr Pulmonol. 2008 Jan;43(1):59-66.
Daniels JA, Maitra A, Lederman HM, and Montgomery E. "Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): A clinicopathologic study and review." Am J Surg Pathol. 2007 Dec;31(12):1800-12.
Alterman N, Fattal-Valevski A, Moyal L, Crawford TO, Lederman HM, Ziv Y, and Shiloh Y. "Ataxia-Telangiectasia: Mild neurological presentation despite null ATM mutation and severe cellular phenotype." Am J Med Genet A. 2007 Aug 15;143A(16):1827-34.
Shreffler WG, Visness CM, Burger M, Cruikshank WW, Lederman HM, de la Morena M, Grindle K, Calatroni A, Sampson HA and Gern JE. "Standardization and performance evaluation of mononuclear cell cytokine secretion assays in a multicenter study." BMC Immunol. 2006 Dec 12;7:29.
Lin, DDM, Crawford TO, Lederman HM, Barker PB. "Proton MR Spectroscopic Imaging in Ataxia-Telangiectasia." Neuropediatrics. 2006 Aug;37(4):241-6.