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Bruce Jeffrey Trock, M.P.H., Ph.D.

Photo of Dr. Bruce Jeffrey Trock, M.P.H., Ph.D.

Director, Division of Epidemiology, Brady Urological Institute at Johns Hopkins

Professor of Urology

Research Interests: Breast cancer; Prostate cancer; Biomarkers of age-related change in the prostate; Biological mechanisms of aging

Contact for Research Inquiries

600 N. Wolfe St.
Jefferson Street. Building, Rm. 149
Baltimore, MD 21287-8915 map

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Background

Dr. Bruce Jeffery Trock is a professor of urology, epidemiology, oncology and environmental health sciences at the Johns Hopkins School of Medicine. He serves as the Director of the Division of Epidemiology in the Brady Urological Institute at Johns Hopkins. His research focuses on breast and prostate cancers.

Dr. Trock received undergraduate degrees in mathematics and physiology at the University of Michigan and Michigan State University, respectively. He returned to the University of Michigan for a master’s in public health with an emphasis in epidemiology, and then completed a Ph.D. in epidemiology at the Johns Hopkins University School of Public Health.

In addition to his faculty appointments at Johns Hopkins, Dr. Trock acts as the Director of the Prostate Cancer Biorepository Network, a collaboration between the Johns Hopkins University School of Medicine, the New York University School of Medicine and the United States Department of Defense that works to acquire high quality, well-annotated biological specimens of advanced stage prostate cancer in order to develop more targeted research investigations that can aid in understanding, treating and ultimately curing the disease.

Dr. Trock has authored or co-authored more than 130 published articles and has been principal or co-principal investigator on numerous research grants. He is a member of the Society for Epidemiologic Research, the American Society of Preventive Oncology and the American Association for Cancer Research.

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Titles

  • Director, Division of Epidemiology, Brady Urological Institute at Johns Hopkins
  • Professor of Urology
  • Professor of Oncology

Education

Degrees

  • B.S., University of Michigan (Michigan) (1974)
  • B.S., Michigan State University (Michigan) (1976)
  • M.P.H., University of Michigan (Michigan) (1979)
  • Ph.D., Johns Hopkins Bloomberg School of Public Health (Maryland) (1986)

Research & Publications

Research Summary

Dr. Trock’s research focuses on biomarkers for the early detection and prognosis of prostate and breast cancer, comparative effectiveness of prostate cancer treatments and etiologic mechanisms (e.g., oxidative stress, senescence pathways, inflammation and diet). He is also interested in statistical issues involving biomarkers and statistical models to explore the relationship between aging and prostate cancer, as well as common pathways linking breast and prostate cancer etiology.

Selected Publications

View all on Pubmed

Tan M, Shao C, Bishop JA, Feng Z, Trock BJ, Westra WH, Ha PK. "Aquaporin-1 Promoter Hypermethylation Is Associated with Improved Prognosis in Salivary Gland Adenoid Cystic Carcinoma." Otolaryngol Head Neck Surg. 2014 Feb 3. [Epub ahead of print]

Inoue LY, Trock BJ, Partin AW, Carter HB, Etzioni R. "Modeling grade progression in an active surveillance study." Stat Med. 2013 Oct 9. doi: 10.1002/sim.6003. [Epub ahead of print].

Darshan M, Zheng Q, Fedor HL, Wyhs N, Yegnasubramanian S, Lee P, Melamed J, Netto GJ, Trock BJ, De Marzo AM, Sfanos KS. "Biobanking of derivatives from radical retropubic and robot-assisted laparoscopic prostatectomy tissues as part of the prostate cancer biorepository network." Prostate. 2014 Jan;74(1):61-9. doi: 10.1002/pros.22730. Epub 2013 Sep 21].

Kaye DR, Hyndman ME, Segal RL, Mettee LZ, Trock BJ, Feng Z, Su LM, Bivalacqua TJ, Pavlovich CP. "Urinary outcomes are significantly affected by nerve sparing quality during radical prostatectomy." Urology. 2013 Dec;82(6):1348-53. doi: 10.1016/j.urology.2013.06.067. Epub 2013 Oct 3

Patel HD, Feng Z, Landis P, Trock BJ, Epstein JI, Carter HB. "Prostate Specific Antigen Velocity Risk Count Predicts Biopsy Reclassification for Men with Very Low Risk Prostate Cancer." J Urol. 2013 Sep 20. pii: S0022-5347(13)05468-2. doi: 10.1016/j.juro.2013.09.029. [Epub ahead of print].

Activities & Honors

Memberships

  • American Association for Cancer Research
  • American Society of Preventive Oncology
  • Society for Epidemiologic Research

Professional Activities

  • Director, Prostate Cancer Biorepository Network
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