Richard F. Ambinder, M.D., Ph.D., Professor
Virology and human cancer; antiviral therapy; antitumor therapy; lymphoma pathogenesis and treatment; immunological approaches to virus-associated malignancies.
Samuel R. Denmeade, M.D., Professor
Targeted therapies for cancer; prodrugs; proteases; peptide libraries.
Phillip A. Dennis, M.D., Ph.D., Professor
Activation of the PI3K/Akt pathway and the biology of lung cancer.
Kelly E. Dooley, M.D., Ph.D., Assistant Professor
Clinical pharmacology of anti-infective agents; Evaluation of new drug regimens for the treatment of tuberculosis and co-treatment of TB and HIV.
Charles W. Flexner, M.D., Professor
Basic and clinical pharmacology of antiretroviral drugs; HIV protease inhibitors and entry inhibitors.
Gary S. Hayward, Ph.D., Professor
Pathways of herpesvirus gene regulation and latency; cis-acting DNA elements that modulate gene expression; mechanisms of positive and negative transcriptional regulation; interaction of viral immediate-early transactivators with nuclear domains; molecular piracy by Kaposi's sarcoma herpesvirus.
S. Diane Hayward, Ph.D., Professor
Epstein-Barr virus and Kaposi's sarcoma virus; viral latency and tumorigenesis; mechanisms of virus-induced cell proliferation; viral mediated epigenetic modification of cell gene expression; notch and wnt pathways.
Craig W. Hendrix, M.D., Professor
Anti-infective drugs; chemoprevention of infectious diseases.
Takanari Inoue, Ph.D., Associate Professor
Synthetic cell biology, neutrophil chemotaxis, spatio-temporal signal compartmentalization, confocal fluorescence imaging, technology development.
Daniel J. Leahy, Ph.D., Professor
Molecular studies of signal transduction.
William G. Nelson, M.D., Ph.D., Professor
Molecular mechanisms of prostatic carcinogenesis; epigenetic alterations in cancer; new approaches to prostate cancer prevention and treatment.
Duojia Pan, Ph.D., Professor
Growth control in normal development and cancer; signal transduction; animal models of cancer.
Brent Petty, M.D., Associate Professor
Antimicrobial chemotherapy; hospital-based medical practices; internal medicine collaboration with ophthalmologic clinical trials.
Kenneth J. Pienta, M.D., Professor
The ecology of cancer, tumor microenvironment, metastasis, biomarker development, novel therapeutic development.
Martin G. Pomper, M.D., Ph.D., Professor
In Vivo molecular and cellular imaging; radiopharmaceutical development; targeted cancer imaging and therapy; functional brain imaging.
Jonathan D. Powell, M.D., Ph.D., Associate Professor
Mechanisms of T cell activation and tolerance.
Douglas N. Robinson, Ph.D., Professor
Understanding cytokinesis and cell shape control.
Christopher A. Ross, M.D., Ph.D., Professor
Theresa A. Shapiro, M.D., Ph.D., Professor
Clinical pharmacology; molecular mechanisms of antiparasitic drug action; effects of topoisomerase inhibitors on DNA of trypanosomes; structure-activity of synthetic antimalarial trioxanes.
Robert F. Siliciano, M.D., Ph.D., Professor
HIV latency, evolution, and persistence; HIV treatment and drug resistance; pharmacology of HIV drugs.
Solomon H. Snyder, M.D., Professor
Molecular basis of neural signal transduction.