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Faculty Who Participate In Our Graduate Program

See Faculty Grouped by Areas of Research

Photo of Dr. Richard F Ambinder, MD

Ambinder, Richard F, MD

Expertise, Disease and Conditions: AIDS-Related Cancers, Bone Marrow Transplant, Epstein-Barr Virus and Cancer, Hematologic Malignancies, Kaposi's Sarcoma, Lymphoma, Lymphoma, Hodgkins Disease, Medical Oncology, Non-Hodgkin's Lymphoma
Research Interests: Lymphoma, Epstein-Barr Virus and Cancer, AIDS Associated Cancers, Virology in human cancer, Antiviral therapy, Antitumor therapy, Lymphoma biology, Kaposi's Sarcoma
Photo of Dr. L. Mario Amzel, Ph.D.

Amzel, L. Mario, Ph.D.

Research Interests: Structural enzymology of redox and phosphoryl-transfer enzymes, MICAL, VP14, PI3K, Nudix hydrolases, Selected areas of structural thermodynamics, Three dimensional structure and mechanism of proteins, Redox and phosphoryl transfer enzymes
Photo of Dr. J. Thomas August, M.D.

August, J. Thomas, M.D.

Research Interests: Genetic immunotherapy of infectious diseases and cancer by targeting DNA encoded antigen chimeras to MHC II, HIV-1 peptide vaccine, Bioinformatic analysis of viral and other protein structures
Photo of Dr. James C. Barrow, Ph.D.

Barrow, James C., Ph.D.

Research Interests: Drug discovery for disorders of neurodeveloment
Photo of Dr. Namandje N. Bumpus, Ph.D.

Bumpus, Namandje N., Ph.D.

Research Interests: Drug metabolism and preclinical drug development, Small molecule mass spectrometry, Targeted metabolomics, Antiviral drug-induced toxicity, Modulation of cellular signaling pathways by reactive metabolites
Photo of Dr. Philip Arthur Cole, M.D., Ph.D.

Cole, Philip Arthur, M.D., Ph.D.

Research Interests: Chemical approaches to the study of signal transduction, gene expression and circadian rhythm, Chemical Activity Probes for Identification of Novel Acetyltransferases
Photo of Dr. Ted M. Dawson, M.D., Ph.D.

Dawson, Ted M., M.D., Ph.D.

Expertise, Disease and Conditions: Neurological Disease, Neurology, Parkinson's Disease
Research Interests: Molecular and Cellular Signals Controlling Neurodegeneration, Neuronal Survival and Cell Death
Photo of Dr. Samuel Ray Denmeade, MD

Denmeade, Samuel Ray, MD

Expertise, Disease and Conditions: Bladder Cancer, Clinical Trials, Kidney Cancer, Medical Oncology, Prostate Cancer, Testicular Cancer
Research Interests: Targeted Drug Development, Bladder Cancer, Prostate and Renal Cancer, Targeted therapies for cancer, Prodrugs, Protoxins, Protease biology, Protease inhibitors, Cancer imaging
Photo of Dr. Phillip Andrew Dennis, MD

Dennis, Phillip Andrew, MD

Expertise, Disease and Conditions: Lung Cancer, Medical Oncology, Mesothelioma, Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Thoracic Cancer
Research Interests: Anti-cancer drug development program, Lung Cancer, Activation of the PI3K/Akt pathway and the biology of lung cancer
Photo of Dr. Kelly Elise Dooley, MD PhD

Dooley, Kelly Elise, MD PhD

Expertise, Disease and Conditions: Infectious Disease
Research Interests: Clinical pharmacology of anti-infective agents, Evaluation of new drug regimens for the treatment of tuberculosis and co-treatment of TB and HIV
Photo of Dr. Charles Williams Flexner, MD

Flexner, Charles Williams, MD

Expertise, Disease and Conditions: Infectious Diseases, Internal Medicine
Research Interests: Antiviral chemotherapy, Clinical Pharmacology, Basic and clinical pharmacology of antiretroviral drugs, HIV protease inhibitors and entry inhibitors
Photo of Dr. D. Wade Gibson, Ph.D.

Gibson, D. Wade, Ph.D.

Research Interests: Viral proteins, Herpesvirus proteins, Cytomegalovirus (CMV), Regulatory mechanisms, Virus assembly and maturation, Antiviral drug development, Maturational protease (CMV ORF UL80a), Deubiquitinylating enzyme (CMV ORF UL48), Basic phosphoprotein (CMV ORF UL32)
Photo of Dr. Carol Widney Greider, Ph.D.

Greider, Carol Widney, Ph.D.

Research Interests: Telomeres, Telomerase, Cell division, Cell viability, Stem cells, DNA damage response, Chromosome maintenance, Chromosome replication, Chromosome stability, Cancer, Autosomal dominant dyskeratosis congenita
Photo of Dr. Justin Scot Hanes, Ph.D.

Hanes, Justin Scot, Ph.D.

Research Interests: Nanomedicine, Drug delivery, Nanotechnology for Drug and Nucleic Acid Delivery
Photo of Dr. S. Diane Hayward, Ph.D.

Hayward, S. Diane, Ph.D.

Research Interests: Herpesvirus-Host Cell Interactions
Photo of Dr. Gary S. Hayward, Ph.D.

Hayward, Gary S., Ph.D.

Research Interests: Pathways of human herpesvirus gene regulation, Latency and pathogenesis, Enhancer and silencer elements that modulate gene expression, Mechanisms of positive and negative transcriptional regulation, Interaction with and targeting to subnuclear domains by viral regulatory proteins, Molecular piracy and promotion of angiogenesis by Kaposi's sarcoma herpesvirus, Virus evasion of interferon-mediated innate immunity, Virus evolution and virus hunting
Photo of Dr. Craig Walter Hendrix, M.D.

Hendrix, Craig Walter, M.D.

Research Interests: Chemoprevention of HIV infection, Topical HIV microbicides, Clinical pharmacology of antiviral drugs, Drug interactions
Photo of Dr. Richard L. Huganir, Ph.D.

Huganir, Richard L., Ph.D.

Research Interests: Regulation of neurotransmitter receptors and brain function in health and disease, Glutamate receptors
Photo of Dr. Takanari Inoue, Ph.D.

Inoue, Takanari, Ph.D.

Research Interests: Synthetic cell biology
Photo of Dr. William B. Isaacs, Ph.D.

Isaacs, William B., Ph.D.

Research Interests: Molecular genetics and cell biology of prostate cancer, Hereditary prostate cancer
Photo of Dr. John T. Isaacs, Ph.D.

Isaacs, John T., Ph.D.

Research Interests: Anti-cancer drug development, Normal and malignant stem cell biology
Photo of Dr. Elizabeth Marion Jaffee, MD

Jaffee, Elizabeth Marion, MD

Expertise, Disease and Conditions: Medical Oncology, Pancreatic Cancer
Research Interests: Vaccine therapies for solid tumors, Mechanisms of induction of mouse and human antitumor immune responses
Photo of Dr. Kenneth W. Kinzler, Ph.D.

Kinzler, Kenneth W., Ph.D.

Research Interests: Molecular genetics of human cancer
Photo of Dr. Daniel J. Leahy, M.D., Ph.D.

Leahy, Daniel J., M.D., Ph.D.

Research Interests: Molecular studies of signal transduction
Photo of Dr. Mark James Levis, MD

Levis, Mark James, MD

Expertise, Disease and Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Leukemia, Medical Oncology, Myelodysplastic Syndrome
Research Interests: Kinase inhibitors, Targeting the FLT3 signaling pathway as a treatment for acute leukemia.
Photo of Dr. Jun Liu, Ph.D.

Liu, Jun, Ph.D.

Research Interests: Chemical biology, Molecular and cellular biology, Translational medicine
Photo of Dr. Caren L. Freel Meyers, M.S., Ph.D.

Meyers, Caren L. Freel, M.S., Ph.D.

Research Interests: Organic and medicinal chemistry, Chemical biology, Drug delivery mechanisms in bacteria, Antibiotic prodrug strategies, Bacterial isoprenoid biosynthesis, Combinatorial biosynthesis, Study of non-mammalian isoprenoid biosynthesis, Development of potential therapeutic agents for cancer and infectious disease
Photo of Dr. William George Nelson, MD

Nelson, William George, MD

Expertise, Disease and Conditions: Medical Oncology, Prostate Cancer
Research Interests: Prostate cancer, Urologic cancers, Drug development, Cellular defenses against carcinogens, Cellular responses to DNA damage, DNA methylation and epigenetic gene silencing, Inflammation and prostatic carcinogenesis
Photo of Dr. Duojia Pan, Ph.D.

Pan, Duojia, Ph.D.

Research Interests: Growth control in normal development and cancer, Signal transduction, Animal models of cancer
Photo of Dr. Brent G Petty, MD

Petty, Brent G, MD

Expertise, Disease and Conditions: General Internal Medicine, Internal Medicine
Research Interests: Phase I Clinical Trials, Phase II and Phase III Clinical Trials, Quality Improvement
Photo of Dr. Kenneth James Pienta, MD

Pienta, Kenneth James, MD

Expertise, Disease and Conditions: Medical Oncology
Research Interests: Ecology of cancer, Tumor microenvironment, Metastasis, Biomarker development, Novel therapeutic development
Photo of Dr. Martin Gilbert Pomper, MD

Pomper, Martin Gilbert, MD

Expertise, Disease and Conditions: Diagnostic Radiology
Research Interests: Molecular imaging, particularly of central nervous system processes and cancer, Development of new radiotracers for PET and SPECT for cancer detection, In Vivo and Molecular Imaging, Radiopharmacology, Oncology, Translational Molecular Imaging
Photo of Dr. Jonathan David Powell, MD

Powell, Jonathan David, MD

Expertise, Disease and Conditions: Bone Marrow Transplant, Medical Oncology
Research Interests: Cancer Immunotherapy, Bone Marrow Transplantation, Mechanisms of T cell activation and tolerance
Photo of Dr. Stuart Campbell Ray, MD

Ray, Stuart Campbell, MD

Expertise, Disease and Conditions: Chronic Viral Hepatitis, Hepatitis, HIV/AIDS, Infectious Disease, Infectious Diseases, Internal Medicine
Research Interests: HIV pathogenesis, Computational biology, Viral Evolution, Hepatitis C immunology, Hepatitis C virology
Photo of Dr. Douglas N. Robinson, M.P.H., Ph.D.

Robinson, Douglas N., M.P.H., Ph.D.

Research Interests: Molecular mechanisms, Cellular mechanosensing, Cytokinesis (Cell division), Tissue development, Homeostasis, Cell-shape control, Model systems, Disease states
Photo of Dr. Christopher A Ross, MD

Ross, Christopher A, MD

Expertise, Disease and Conditions: Adult Psychiatry, Huntington's Disease, Movement Disorders
Research Interests: Neuropsychiatric disorders
Photo of Dr. Ronald L. Schnaar, Ph.D.

Schnaar, Ronald L., Ph.D.

Research Interests: Neuroglycobiology, Glycobiology, Cell-cell interactions in the nervous system
Photo of Dr. Theresa A. Shapiro, M.D., Ph.D.

Shapiro, Theresa A., M.D., Ph.D.

Research Interests: Molecular and clinical pharmacology of antiparasitic drugs, DNA topoisomerases as antiparasitic drug targets, Structure-activity of synthetic antimalarial trioxanes
Photo of Dr. Robert Francis Siliciano, M.D., Ph.D.

Siliciano, Robert Francis, M.D., Ph.D.

Research Interests: Drug therapy for HIV infection
Photo of Dr. Solomon H. Snyder, D.Phil., D.Sc., M.D.

Snyder, Solomon H., D.Phil., D.Sc., M.D.

Research Interests: Neurotransmitters, second messengers and drug action in the nervous system
Photo of Dr. James T. Stivers, Ph.D.

Stivers, James T., Ph.D.

Research Interests: Structural and chemical biology of uracil metabolism and applications to cancer therapy, Viral Pathogenesis, Innate and adaptive immunity
Photo of Dr. Saraswati Sukumar, Ph.D.

Sukumar, Saraswati, Ph.D.

Research Interests: Molecular alterations in breast cancer
Photo of Dr. Sean Dixon Taverna, Ph.D.

Taverna, Sean Dixon, Ph.D.

Research Interests: Histone and chromatin modifications, Epigenetics and gene function, Identification of histone binding modules, Small RNA directed gene silencing
Photo of Dr. Bert Vogelstein, M.D.

Vogelstein, Bert, M.D.

Research Interests: Molecular genetics of human colorectal cancer
Photo of Dr. Srinivasan Yegnasubramanian, M.D., Ph.D.

Yegnasubramanian, Srinivasan, M.D., Ph.D.

Research Interests: Understanding and exploiting alterations in the cancer genome and epigenome for development of biomarkers and therapeutics
Photo of Dr. Jin Zhang, Ph.D.

Zhang, Jin, Ph.D.

Research Interests: Spatiotemporal regulation of signal transduction
Photo of Dr. Heng Zhu, Ph.D.

Zhu, Heng, Ph.D.

Research Interests: Signal transduction, Protein networks, Host-pathogen interaction, Protein chip approach to study proteomics, Systems biology, Transcription regulation, Viral oncology

Darrell R. Abernethy, M.D., Ph.D.
Role of genetic polymorphisms of drug effectors that effect responses to cardiovascular drugs.

Albena Dinkova-Kostova, Ph.D., Assistant Professor
Protection against cancer mechanisms and strategies; structure-activity relation of protective agents; inflammation and cancer; skin cancer prevention.

Marc M. Greenberg, Ph.D., Professor
Chemical and biochemical approaches to the study of DNA damage and repair, and their applications.

J. Marie Hardwick, Ph.D.,Professor
Molecular mechanisms of programmed cell death.

Paula M. Pitha-Rowe, Ph.D., Professor
Effects of viral infection on expression of cellular (cytokines and chemokines and their receptors) and viral (HIV-1, HHV-8) genes; targeted antiviral and anticellular therapy (gene transfer, ribozymes); breast cancer: role of c-erbB-2.

Molecular mechanisms involved in chemoprotection against mutagens and carcinogens.

Craig A. Townsend, Ph.D., Professor
Organic and bioorganic chemistry: biosynthesis of natural products and biomimetic synthesis; elucidation of protein function; molecular biology of secondary metabolism and engineering of biosynthetic systems to practical ends; study of the role and inhibition of fatty acid synthesis in human cancer, tuberculosis, and obesity.


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